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IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) | ||||
F2RL1 | Proteinase-activated receptor 2. (315 aa) | ||||
FAM49B | Protein FAM49B isoform X1. (324 aa) | ||||
NOD2 | Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa) | ||||
ISL1 | Insulin gene enhancer protein ISL-1. (349 aa) | ||||
LOC111165935 | Ras-like protein isoform X1. (285 aa) | ||||
TYK2 | Tyrosine-protein kinase. (1188 aa) | ||||
RARA | Retinoic acid receptor alpha isoform X5. (584 aa) | ||||
CCR7 | C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) | ||||
SLAMF6 | SLAM family member 6 isoform X1. (335 aa) | ||||
IL27RA | Interleukin-27 receptor subunit alpha isoform X1. (656 aa) | ||||
IL12RB1 | Interleukin-12 receptor subunit beta-1 isoform X1. (726 aa) | ||||
LOC111167004 | LOW QUALITY PROTEIN: peptidoglycan recognition protein 3-like. (277 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
TLR7 | Toll-like receptor 7 isoform X1. (1086 aa) | ||||
TLR8 | Toll-like receptor 8; Belongs to the Toll-like receptor family. (1035 aa) | ||||
CRTAM | Cytotoxic and regulatory T-cell molecule isoform X1. (391 aa) | ||||
SASH3 | SAM and SH3 domain-containing protein 3. (380 aa) | ||||
LOC111168424 | Zinc finger protein RFP. (513 aa) | ||||
SLAMF1 | Signaling lymphocytic activation molecule isoform X1. (378 aa) | ||||
PGLYRP2 | N-acetylmuramoyl-L-alanine amidase isoform X1. (581 aa) | ||||
FOXP3 | Forkhead box protein P3. (431 aa) | ||||
HRAS | GTPase HRas isoform X1. (189 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
IL1RL1 | Interleukin-1 receptor-like 1 isoform X1. (592 aa) | ||||
ARID5A | AT-rich interactive domain-containing protein 5A isoform X1. (593 aa) | ||||
IL1R1 | Interleukin-1 receptor type 1 isoform X1. (686 aa) | ||||
IL36RN | Interleukin-1. (155 aa) | ||||
NR1H4 | Bile acid receptor isoform X1. (486 aa) | ||||
LGALS9 | Galectin. (356 aa) | ||||
IL18R1 | Interleukin-18 receptor 1 isoform X1. (539 aa) | ||||
PDE4D | Phosphodiesterase. (805 aa) | ||||
C1QBP | Complement component 1 Q subcomponent-binding protein, mitochondrial. (278 aa) | ||||
IL10 | Interleukin-10. (178 aa) | ||||
TICAM2 | TIR domain-containing adapter molecule 2. (235 aa) | ||||
VSIR | V-type immunoglobulin domain-containing suppressor of T-cell activation. (311 aa) | ||||
CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) | ||||
IL27 | Interleukin-27 subunit alpha. (237 aa) | ||||
ZP3 | Zona pellucida sperm-binding protein 3. (421 aa) | ||||
RASGRP1 | RAS guanyl-releasing protein 1 isoform X1. (870 aa) | ||||
CD226 | CD226 antigen. (335 aa) | ||||
PYCARD | Apoptosis-associated speck-like protein containing a CARD. (195 aa) | ||||
CD2 | T-cell surface antigen CD2 isoform X1. (340 aa) | ||||
SLC7A5 | Large neutral amino acids transporter small subunit 1 isoform X1. (505 aa) | ||||
BCL3 | B-cell lymphoma 3 protein. (454 aa) | ||||
PDE4B | Phosphodiesterase. (736 aa) | ||||
CEBPG | CCAAT/enhancer-binding protein gamma. (149 aa) | ||||
AXL | LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa) | ||||
GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa) | ||||
IL12RB2 | Interleukin-12 receptor subunit beta-2 isoform X1. (861 aa) | ||||
IL20RB | Interleukin-20 receptor subunit beta isoform X1. (342 aa) | ||||
IRF8 | Interferon regulatory factor 8 isoform X1. (427 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1148 aa) | ||||
LOC111176900 | GTPase IMAP family member 5-like isoform X1. (332 aa) | ||||
ZFPM1 | Zinc finger protein ZFPM1 isoform X1. (1069 aa) | ||||
LRRC1 | Leucine-rich repeat-containing protein 1. (395 aa) | ||||
LOC111178657 | Leucine-rich repeat-containing protein 1-like isoform X1. (174 aa) | ||||
GAS6 | Growth arrest-specific protein 6. (671 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) | ||||
LOC111176754 | C-type lectin domain family 7 member A-like isoform X1. (244 aa) | ||||
ZC3H12A | Endoribonuclease ZC3H12A. (583 aa) | ||||
CD96 | LOW QUALITY PROTEIN: T-cell surface protein tactile. (546 aa) | ||||
TLR9 | LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa) | ||||
DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) | ||||
TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa) | ||||
HSPD1 | 60 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (573 aa) | ||||
TNFSF4 | Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (182 aa) | ||||
TXK | Tyrosine-protein kinase. (550 aa) | ||||
SLC11A1 | Natural resistance-associated macrophage protein 1 isoform X1. (546 aa) | ||||
FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa) | ||||
LTA | Lymphotoxin-alpha; Belongs to the tumor necrosis factor family. (205 aa) | ||||
NLRP6 | LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 6. (876 aa) |