Your Input: | |||||
RAB7B | Ras-related protein Rab-7b isoform X1. (210 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
Ob | Leptin isoform X1. (167 aa) | ||||
TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa) | ||||
TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) | ||||
IL1RL2 | Interleukin-1 receptor-like 2 isoform X1. (570 aa) | ||||
ARID5A | AT-rich interactive domain-containing protein 5A isoform X1. (593 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa) | ||||
C1QTNF3 | Complement C1q tumor necrosis factor-related protein 3 isoform X1. (319 aa) | ||||
EREG | Proepiregulin. (163 aa) | ||||
IL36RN | Interleukin-1. (155 aa) | ||||
NR1H4 | Bile acid receptor isoform X1. (486 aa) | ||||
CEBPB | CCAAT/enhancer-binding protein. (345 aa) | ||||
NLRC3 | NLR family CARD domain-containing protein 3 isoform X1. (1066 aa) | ||||
F2R | Proteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa) | ||||
LOC111185989 | Nitric oxide synthase; Produces nitric oxide (NO). (1146 aa) | ||||
ARRB2 | Beta-arrestin-2 isoform X1. (409 aa) | ||||
ARRB1 | Beta-arrestin-1 isoform X1. (430 aa) | ||||
MAVS | Mitochondrial antiviral-signaling protein isoform X1. (581 aa) | ||||
LBP | Lipopolysaccharide-binding protein isoform X1. (537 aa) | ||||
MAPKAPK2 | LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (414 aa) | ||||
GHSR | Growth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (366 aa) | ||||
IL10 | Interleukin-10. (178 aa) | ||||
TICAM2 | TIR domain-containing adapter molecule 2. (235 aa) | ||||
DHX9 | ATP-dependent RNA helicase A isoform X1. (1253 aa) | ||||
BPI | Bactericidal permeability-increasing protein isoform X1. (483 aa) | ||||
TWIST1 | Twist-related protein 1. (205 aa) | ||||
C1QTNF4 | Complement C1q tumor necrosis factor-related protein 4 isoform X1. (329 aa) | ||||
CD74 | HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa) | ||||
TMEM130 | Transmembrane protein 130 isoform X1. (435 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa) | ||||
FOXJ1 | Forkhead box protein J1. (422 aa) | ||||
SPHK2 | Sphingosine kinase 2 isoform X1. (655 aa) | ||||
PTPN22 | Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (801 aa) | ||||
PYCARD | Apoptosis-associated speck-like protein containing a CARD. (195 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) | ||||
POU2F2 | POU domain protein. (614 aa) | ||||
C5AR2 | C5a anaphylatoxin chemotactic receptor 2 isoform X1. (343 aa) | ||||
NOD1 | Nucleotide-binding oligomerization domain-containing protein 1 isoform X1. (953 aa) | ||||
TREM2 | Triggering receptor expressed on myeloid cells 2. (294 aa) | ||||
BANK1 | B-cell scaffold protein with ankyrin repeats isoform X1. (785 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) | ||||
IL17F | interleukin-17F. (165 aa) | ||||
LOC111179403 | Cytochrome b-245 light chain isoform X1. (202 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (366 aa) | ||||
IL17RA | Interleukin-17 receptor A isoform X1. (847 aa) | ||||
CARD9 | Caspase recruitment domain-containing protein 9 isoform X1. (539 aa) | ||||
IL17A | interleukin-17A. (155 aa) | ||||
GAS6 | Growth arrest-specific protein 6. (671 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) | ||||
APP | Amyloid beta A4 protein isoform X1. (767 aa) | ||||
HYAL2 | Hyaluronidase. (476 aa) | ||||
LOC111176754 | C-type lectin domain family 7 member A-like isoform X1. (244 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) | ||||
ZC3H12A | Endoribonuclease ZC3H12A. (583 aa) | ||||
F2RL1 | Proteinase-activated receptor 2. (315 aa) | ||||
AKIRIN2 | Akirin-2. (203 aa) | ||||
SETD4 | SET domain-containing protein 4. (440 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) | ||||
HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa) | ||||
NOD2 | Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa) | ||||
ISL1 | Insulin gene enhancer protein ISL-1. (349 aa) | ||||
ZBTB20 | Zinc finger and BTB domain-containing protein 20 isoform X1. (741 aa) | ||||
TNFAIP3 | Tumor necrosis factor alpha-induced protein 3. (785 aa) | ||||
SYT11 | Synaptotagmin-11 isoform X1. (428 aa) | ||||
IL27RA | Interleukin-27 receptor subunit alpha isoform X1. (656 aa) | ||||
CD84 | SLAM family member 5 isoform X1. (341 aa) | ||||
GBA | Glucosylceramidase. (585 aa) | ||||
MBP | Myelin basic protein isoform X1. (326 aa) | ||||
TLR7 | Toll-like receptor 7 isoform X1. (1086 aa) | ||||
TLR8 | Toll-like receptor 8; Belongs to the Toll-like receptor family. (1035 aa) | ||||
NLRX1 | NLR family member X1 isoform X1. (973 aa) | ||||
ARHGEF2 | Rho guanine nucleotide exchange factor 2 isoform X1. (1032 aa) | ||||
CUNHXorf40A | Protein CXorf40A homolog isoform X1. (158 aa) | ||||
ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (333 aa) | ||||
LOC111165753 | NACHT, LRR and PYD domains-containing protein 12 isoform X2. (1105 aa) | ||||
MMP8 | Neutrophil collagenase isoform X1. (468 aa) | ||||
POU2AF1 | POU domain class 2-associating factor 1. (256 aa) | ||||
CUNH1orf106 | Uncharacterized protein C1orf106 homolog. (540 aa) | ||||
SLAMF1 | Signaling lymphocytic activation molecule isoform X1. (378 aa) | ||||
LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (478 aa) | ||||
NMBR | LOW QUALITY PROTEIN: neuromedin-B receptor. (394 aa) | ||||
FOXP3 | Forkhead box protein P3. (431 aa) | ||||
TMEM106A | Transmembrane protein 106A isoform X1. (293 aa) | ||||
SYK | Tyrosine-protein kinase. (626 aa) | ||||
IL17RC | Interleukin-17 receptor C isoform X1. (713 aa) | ||||
AIF1 | Allograft inflammatory factor 1 isoform X1. (162 aa) | ||||
AGER | Advanced glycosylation end product-specific receptor isoform X1. (631 aa) | ||||
LOC111171320 | Mucin-16-like. (855 aa) | ||||
TNFSF4 | Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (182 aa) | ||||
IFIH1 | Interferon-induced helicase C domain-containing protein 1. (1023 aa) | ||||
HSPD1 | 60 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (573 aa) | ||||
INPP5D | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa) | ||||
AFAP1L2 | Actin filament-associated protein 1-like 2 isoform X1. (938 aa) | ||||
NCKAP1L | Nck-associated protein 1-like isoform X1. (1156 aa) | ||||
TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa) | ||||
SOCS5 | Suppressor of cytokine signaling 5. (536 aa) | ||||
IL17D | interleukin-17D. (309 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa) | ||||
TLR9 | LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa) | ||||
UCN | Urocortin. (126 aa) | ||||
IRAK3 | Interleukin-1 receptor-associated kinase 3 isoform X2. (674 aa) | ||||
IL1RAP | Interleukin-1 receptor accessory protein isoform X2. (685 aa) |