STRINGSTRING
PTPN6 PTPN6 INPP5D INPP5D NCKAP1L NCKAP1L SOCS5 SOCS5 TLR9 TLR9 IRAK3 IRAK3 GHSR GHSR ZC3H12A ZC3H12A GAS6 GAS6 BANK1 BANK1 C5AR2 C5AR2 PTPN22 PTPN22 FOXJ1 FOXJ1 TMEM130 TMEM130 BPI BPI IL10 IL10 ARRB1 ARRB1 ARRB2 ARRB2 NLRC3 NLRC3 NR1H4 NR1H4 IL36RN IL36RN C1QTNF3 C1QTNF3 TNF TNF LOC111171320 LOC111171320 FOXP3 FOXP3 NMBR NMBR SLAMF1 SLAMF1 LOC111165753 LOC111165753 NLRX1 NLRX1 GBA GBA CD84 CD84 IL27RA IL27RA SYT11 SYT11 TNFAIP3 TNFAIP3 HGF HGF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
NCKAP1LNck-associated protein 1-like isoform X1. (1156 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
TLR9LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa)
IRAK3Interleukin-1 receptor-associated kinase 3 isoform X2. (674 aa)
GHSRGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ZC3H12AEndoribonuclease ZC3H12A. (583 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
BANK1B-cell scaffold protein with ankyrin repeats isoform X1. (785 aa)
C5AR2C5a anaphylatoxin chemotactic receptor 2 isoform X1. (343 aa)
PTPN22Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (801 aa)
FOXJ1Forkhead box protein J1. (422 aa)
TMEM130Transmembrane protein 130 isoform X1. (435 aa)
BPIBactericidal permeability-increasing protein isoform X1. (483 aa)
IL10Interleukin-10. (178 aa)
ARRB1Beta-arrestin-1 isoform X1. (430 aa)
ARRB2Beta-arrestin-2 isoform X1. (409 aa)
NLRC3NLR family CARD domain-containing protein 3 isoform X1. (1066 aa)
NR1H4Bile acid receptor isoform X1. (486 aa)
IL36RNInterleukin-1. (155 aa)
C1QTNF3Complement C1q tumor necrosis factor-related protein 3 isoform X1. (319 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
LOC111171320Mucin-16-like. (855 aa)
FOXP3Forkhead box protein P3. (431 aa)
NMBRLOW QUALITY PROTEIN: neuromedin-B receptor. (394 aa)
SLAMF1Signaling lymphocytic activation molecule isoform X1. (378 aa)
LOC111165753NACHT, LRR and PYD domains-containing protein 12 isoform X2. (1105 aa)
NLRX1NLR family member X1 isoform X1. (973 aa)
GBAGlucosylceramidase. (585 aa)
CD84SLAM family member 5 isoform X1. (341 aa)
IL27RAInterleukin-27 receptor subunit alpha isoform X1. (656 aa)
SYT11Synaptotagmin-11 isoform X1. (428 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (785 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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