37 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRKL	Crk-like protein. (303 aa)
	LIF	Leukemia inhibitory factor. (202 aa)
	EPHA8	Ephrin type-A receptor 8. (1005 aa)
	CCL21	C-C motif chemokine 21 isoform X1. (131 aa)
	RET	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1113 aa)
	ITGB1BP1	Integrin beta-1-binding protein 1 isoform X1. (206 aa)
	IFT74	Intraflagellar transport protein 74 homolog isoform X1. (600 aa)
	FERMT1	Fermitin family homolog 1. (677 aa)
	SWAP70	Switch-associated protein 70. (585 aa)
	SNAI2	Zinc finger protein SNAI2. (268 aa)
	LYN	Tyrosine-protein kinase. (518 aa)
	JAM3	Junctional adhesion molecule C. (301 aa)
	MUC1	Mucin-1. (363 aa)
	EFNA1	ephrin-A1 isoform X3; Belongs to the ephrin family. (211 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	CIB1	Calcium and integrin-binding protein 1. (191 aa)
	DPP4	Dipeptidyl peptidase 4 isoform X1; Belongs to the peptidase S9B family. (804 aa)
	NCKAP1L	Nck-associated protein 1-like isoform X1. (1156 aa)
	ADAM9	Disintegrin and metalloproteinase domain-containing protein 9 isoform X1. (841 aa)
	ACER2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (276 aa)
	LOC111174870	Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	NEXMIF	Protein KIAA2022 homolog. (1515 aa)
	DEF6	Differentially expressed in FDCP 6 homolog isoform X1. (673 aa)
	WNK1	Serine/threonine-protein kinase WNK1 isoform X1. (2825 aa)
	PODXL	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (532 aa)
	PLAU	Urokinase-type plasminogen activator. (431 aa)
	LRRC45	Leucine-rich repeat-containing protein 45 isoform X1. (703 aa)
	FERMT3	Fermitin family homolog 3. (663 aa)
	LPXN	Leupaxin isoform X2; Belongs to the paxillin family. (387 aa)
	CRK	Adapter molecule crk isoform X1. (304 aa)
	ADA	Adenosine deaminase isoform X1. (416 aa)
	EPHA2	Ephrin type-A receptor 2. (975 aa)
	TESC	Calcineurin B homologous protein 3. (214 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
	LOC111187154	Ephrin type-A receptor 2-like. (171 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	DPP4	A0A2Y9PY23	A0A2Y9MUJ3	Adenosine deaminase isoform X1.	Dipeptidyl peptidase 4 isoform X1; Belongs to the peptidase S9B family.	0.969
CRK	CRKL	A0A2Y9PWG4	A0A2Y9LB74	Adapter molecule crk isoform X1.	Crk-like protein.	0.961
CRK	EPHA2	A0A2Y9PWG4	A0A2Y9Q9I4	Adapter molecule crk isoform X1.	Ephrin type-A receptor 2.	0.753
CRK	LPXN	A0A2Y9PWG4	A0A2Y9PPI2	Adapter molecule crk isoform X1.	Leupaxin isoform X2; Belongs to the paxillin family.	0.699
CRK	LYN	A0A2Y9PWG4	A0A2Y9LZZ2	Adapter molecule crk isoform X1.	Tyrosine-protein kinase.	0.452
CRK	NCKAP1L	A0A2Y9PWG4	A0A2Y9N0G9	Adapter molecule crk isoform X1.	Nck-associated protein 1-like isoform X1.	0.561
CRK	RET	A0A2Y9PWG4	A0A2Y9LJM0	Adapter molecule crk isoform X1.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.439
CRK	SYK	A0A2Y9PWG4	A0A2Y9MGM5	Adapter molecule crk isoform X1.	Tyrosine-protein kinase.	0.509
CRKL	CRK	A0A2Y9LB74	A0A2Y9PWG4	Crk-like protein.	Adapter molecule crk isoform X1.	0.961
CRKL	EPHA2	A0A2Y9LB74	A0A2Y9Q9I4	Crk-like protein.	Ephrin type-A receptor 2.	0.730
CRKL	EPHA8	A0A2Y9LB74	A0A2Y9LDB2	Crk-like protein.	Ephrin type-A receptor 8.	0.468
CRKL	LPXN	A0A2Y9LB74	A0A2Y9PPI2	Crk-like protein.	Leupaxin isoform X2; Belongs to the paxillin family.	0.649
CRKL	LYN	A0A2Y9LB74	A0A2Y9LZZ2	Crk-like protein.	Tyrosine-protein kinase.	0.652
CRKL	NCKAP1L	A0A2Y9LB74	A0A2Y9N0G9	Crk-like protein.	Nck-associated protein 1-like isoform X1.	0.409
CRKL	PTPN11	A0A2Y9LB74	A0A2Y9QEG1	Crk-like protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.429
CRKL	SYK	A0A2Y9LB74	A0A2Y9MGM5	Crk-like protein.	Tyrosine-protein kinase.	0.408
DPP4	ADA	A0A2Y9MUJ3	A0A2Y9PY23	Dipeptidyl peptidase 4 isoform X1; Belongs to the peptidase S9B family.	Adenosine deaminase isoform X1.	0.969
EFNA1	EPHA2	A0A2Y9MCV7	A0A2Y9Q9I4	ephrin-A1 isoform X3; Belongs to the ephrin family.	Ephrin type-A receptor 2.	0.980
EFNA1	EPHA8	A0A2Y9MCV7	A0A2Y9LDB2	ephrin-A1 isoform X3; Belongs to the ephrin family.	Ephrin type-A receptor 8.	0.930
EFNA1	LOC111187154	A0A2Y9MCV7	A0A2Y9QFY4	ephrin-A1 isoform X3; Belongs to the ephrin family.	Ephrin type-A receptor 2-like.	0.946