19 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SH3BP4	SH3 domain-binding protein 4 isoform X1. (959 aa)
	SPRY2	Protein sprouty homolog 2. (315 aa)
	BBS4	Bardet-Biedl syndrome 4 protein isoform X1. (528 aa)
	TTC8	Tetratricopeptide repeat protein 8 isoform X1. (515 aa)
	LRCH1	Leucine-rich repeat and calponin homology domain-containing protein 1 isoform X7. (762 aa)
	LRRK2	Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2527 aa)
	FZD10	Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
	SPRY1	Protein sprouty homolog 1. (319 aa)
	WNK1	Serine/threonine-protein kinase WNK1 isoform X1. (2825 aa)
	ARFGEF1	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X1. (1849 aa)
	ARL2	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	DAB2IP	Disabled homolog 2-interacting protein isoform X1. (1193 aa)
	RCC2	Protein RCC2 isoform X1. (543 aa)
	AMOT	Angiomotin isoform X1. (1081 aa)
	LOC111165935	Ras-like protein isoform X1. (285 aa)
	GMIP	GEM-interacting protein isoform X1. (974 aa)
	F11R	Junctional adhesion molecule A. (299 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	PLXNB3	plexin-B3 isoform X1. (1986 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL2	HRAS	A0A2Y9PV80	A0A2Y9MGR2	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	GTPase HRas isoform X1.	0.472
ARL2	LOC111165935	A0A2Y9PV80	A0A2Y9LSR3	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	Ras-like protein isoform X1.	0.472
BBS4	TTC8	A0A2Y9NKP2	A0A2Y9NB09	Bardet-Biedl syndrome 4 protein isoform X1.	Tetratricopeptide repeat protein 8 isoform X1.	0.998
DAB2IP	HRAS	A0A2Y9NXW3	A0A2Y9MGR2	Disabled homolog 2-interacting protein isoform X1.	GTPase HRas isoform X1.	0.428
DAB2IP	LOC111165935	A0A2Y9NXW3	A0A2Y9LSR3	Disabled homolog 2-interacting protein isoform X1.	Ras-like protein isoform X1.	0.428
HRAS	ARL2	A0A2Y9MGR2	A0A2Y9PV80	GTPase HRas isoform X1.	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	0.472
HRAS	DAB2IP	A0A2Y9MGR2	A0A2Y9NXW3	GTPase HRas isoform X1.	Disabled homolog 2-interacting protein isoform X1.	0.428
HRAS	SPRY2	A0A2Y9MGR2	A0A2Y9NMR6	GTPase HRas isoform X1.	Protein sprouty homolog 2.	0.410
LOC111165935	ARL2	A0A2Y9LSR3	A0A2Y9PV80	Ras-like protein isoform X1.	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	0.472
LOC111165935	DAB2IP	A0A2Y9LSR3	A0A2Y9NXW3	Ras-like protein isoform X1.	Disabled homolog 2-interacting protein isoform X1.	0.428
LRCH1	SH3BP4	A0A2Y9N8H4	A0A2Y9MP52	Leucine-rich repeat and calponin homology domain-containing protein 1 isoform X7.	SH3 domain-binding protein 4 isoform X1.	0.495
SH3BP4	LRCH1	A0A2Y9MP52	A0A2Y9N8H4	SH3 domain-binding protein 4 isoform X1.	Leucine-rich repeat and calponin homology domain-containing protein 1 isoform X7.	0.495
SPRY1	SPRY2	A0A2Y9Q360	A0A2Y9NMR6	Protein sprouty homolog 1.	Protein sprouty homolog 2.	0.548
SPRY2	HRAS	A0A2Y9NMR6	A0A2Y9MGR2	Protein sprouty homolog 2.	GTPase HRas isoform X1.	0.410
SPRY2	SPRY1	A0A2Y9NMR6	A0A2Y9Q360	Protein sprouty homolog 2.	Protein sprouty homolog 1.	0.548
TTC8	BBS4	A0A2Y9NB09	A0A2Y9NKP2	Tetratricopeptide repeat protein 8 isoform X1.	Bardet-Biedl syndrome 4 protein isoform X1.	0.998