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CLDN2 CLDN2 MECP2 MECP2 LOC111171406 LOC111171406 TNS1 TNS1 GABRA2 GABRA2 FBXO45 FBXO45 PKP3 PKP3 SDK1 SDK1 DLG1 DLG1 ERBB4 ERBB4 HEG1 HEG1 IL1RAPL2 IL1RAPL2 CDHR2 CDHR2 LOC111169891 LOC111169891 PAK2 PAK2 CDH22 CDH22 WDR1 WDR1 GJC1 GJC1 LGI2 LGI2 FSCN1 FSCN1 CLDN1 CLDN1 CLDN23 CLDN23 ILDR1 ILDR1 ZNF703 ZNF703 ACTN1 ACTN1 NLGN1 NLGN1 ECT2 ECT2 LOC111171048 LOC111171048 COL17A1 COL17A1 GPM6A GPM6A CLDN11 CLDN11 HDAC7 HDAC7 FN1 FN1 BSN BSN PLXNB1 PLXNB1 FERMT2 FERMT2 STON1 STON1 CLDN8 CLDN8 GJB6 GJB6 LOC111173597 LOC111173597 CLDN19 CLDN19 PKP4 PKP4 TTN TTN GJB2 GJB2 RHOA RHOA SLITRK6 SLITRK6 THSD1 THSD1 SLITRK3 SLITRK3 CLDN10 CLDN10 SLITRK1 SLITRK1 RHOB RHOB CLDN17 CLDN17 NTNG2 NTNG2 APP APP PATJ PATJ ZDHHC12 ZDHHC12 CLSTN3 CLSTN3 MYO9A MYO9A PEAK1 PEAK1 PKP2 PKP2 CLDN16 CLDN16 NPTN NPTN LOC111178591 LOC111178591 PTPRO PTPRO DST DST CDK5 CDK5 SRF SRF ADGRF1 ADGRF1 CORO2B CORO2B LOC111178986 LOC111178986 CTNND2 CTNND2 CDH9 CDH9 CLDN18 CLDN18 GRID2 GRID2 CDH18 CDH18 GJA5 GJA5 LRRC4 LRRC4 MPP7 MPP7 RHOC RHOC NPHS1 NPHS1 CDH12 CDH12 CDH20 CDH20 CDH5 CDH5 IGSF22 IGSF22 HIPK1 HIPK1 MARVELD3 MARVELD3 CDH1 CDH1 CDH7 CDH7 CLDN15 CLDN15 BCL2 BCL2 LSR LSR CDC42 CDC42 BCR BCR CLDN5 CLDN5 CRKL CRKL PLXND1 PLXND1 NLGN4X NLGN4X PCDH17 PCDH17 OPHN1 OPHN1 CLDN25 CLDN25 OCEL1 OCEL1 NLGN3 NLGN3 CBLN2 CBLN2 RCC2 RCC2 ARVCF ARVCF VMP1 VMP1 ACTN2 ACTN2 JAM3 JAM3 FLCN FLCN ESAM ESAM RAB13 RAB13 KIRREL3 KIRREL3 RAMP2 RAMP2 PKN2 PKN2 GJA10 GJA10 AJUBA AJUBA PTPRK PTPRK CLDN14 CLDN14 GNPAT GNPAT CBLN1 CBLN1 LOC111165064 LOC111165064 CDH24 CDH24 JUP JUP CDH11 CDH11 CDH8 CDH8 SPTBN2 SPTBN2 RHOD RHOD LRRTM3 LRRTM3 CLDN4 CLDN4 VCL VCL ACTG1 ACTG1 PRKCA PRKCA SDK2 SDK2 CDH2 CDH2 LOC111182630 LOC111182630 CTNNA1 CTNNA1 CLDN3 CLDN3 FBF1 FBF1 ITGB3 ITGB3 SMAD7 SMAD7 CDH19 CDH19 TAOK2 TAOK2 CAPZA1 CAPZA1 TRPV4 TRPV4 TLN1 TLN1 CORO2A CORO2A CBLN4 CBLN4 GABRB3 GABRB3 DVL1 DVL1 NR1H4 NR1H4 PARD6B PARD6B GABRG2 GABRG2 LOC111186242 LOC111186242 CLDN9 CLDN9 SHANK3 SHANK3 PLXNB2 PLXNB2 UGT8 UGT8 NLGN2 NLGN2 MARVELD2 MARVELD2 ASIC2 ASIC2 CLDN7 CLDN7 LAMC1 LAMC1 GABRB2 GABRB2 GABRA1 GABRA1 CLDN6 CLDN6 LRP4 LRP4 FLRT3 FLRT3 DLG2 DLG2 RAB29 RAB29 ARL2 ARL2 MYPN MYPN DLG5 DLG5 DBNL DBNL SRC SRC NPAS4 NPAS4 WNT11 WNT11 TBCD TBCD ITGB4 ITGB4 CTNND1 CTNND1 PECAM1 PECAM1 ACTN3 ACTN3 HAPLN4 HAPLN4 CTNNB1 CTNNB1 DCHS1 DCHS1 ADGRL3 ADGRL3 PIP5K1A PIP5K1A CDH6 CDH6 PKP1 PKP1 THY1 THY1 ACTB ACTB ADD2 ADD2 LOC111171390 LOC111171390
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (486 aa)
LOC111171406Neuroligin-2. (301 aa)
TNS1Tensin-1 isoform X1. (1914 aa)
GABRA2Gamma-aminobutyric acid receptor subunit alpha-2 isoform X2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
FBXO45F-box/SPRY domain-containing protein 1. (283 aa)
PKP3Plakophilin-3 isoform X1. (811 aa)
SDK1Protein sidekick-1 isoform X1. (1942 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
HEG1Protein HEG homolog 1 isoform X1. (1474 aa)
IL1RAPL2X-linked interleukin-1 receptor accessory protein-like 2. (686 aa)
CDHR2Cadherin-related family member 2. (1311 aa)
LOC111169891Uncharacterized protein. (320 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
CDH22Cadherin-22 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (832 aa)
WDR1WD repeat-containing protein 1. (606 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
LGI2Leucine-rich repeat LGI family member 2. (545 aa)
FSCN1Fascin. (493 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN23Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (293 aa)
ILDR1Immunoglobulin-like domain-containing receptor 1. (459 aa)
ZNF703Zinc finger protein 703. (585 aa)
ACTN1Alpha-actinin-1 isoform X2. (914 aa)
NLGN1Neuroligin-1 isoform X1. (843 aa)
ECT2Protein ECT2 isoform X1. (973 aa)
LOC111171048Neuroligin-2-like. (664 aa)
COL17A1Collagen alpha-1(XVII) chain isoform X1. (1515 aa)
GPM6ANeuronal membrane glycoprotein M6-a isoform X1. (293 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1049 aa)
FN1Fibronectin isoform X5. (2478 aa)
BSNProtein bassoon isoform X1. (3915 aa)
PLXNB1plexin-B1 isoform X1. (2182 aa)
FERMT2Fermitin family homolog 2 isoform X2. (691 aa)
STON1Stonin-1; Belongs to the Stoned B family. (730 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
LOC111173597Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
PKP4Plakophilin-4 isoform X1. (1193 aa)
TTNTitin. (32000 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
RHOATransforming protein RhoA. (193 aa)
SLITRK6SLIT and NTRK-like protein 6. (842 aa)
THSD1Thrombospondin type-1 domain-containing protein 1 isoform X1. (844 aa)
SLITRK3SLIT and NTRK-like protein 3. (979 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
SLITRK1SLIT and NTRK-like protein 1. (696 aa)
RHOBRho-related GTP-binding protein RhoB. (196 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
NTNG2netrin-G2 isoform X1. (636 aa)
APPAmyloid beta A4 protein isoform X1. (767 aa)
PATJinaD-like protein isoform X1. (1900 aa)
ZDHHC12Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (342 aa)
CLSTN3Calsyntenin-3 isoform X1. (957 aa)
MYO9AUnconventional myosin-IXa isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2648 aa)
PEAK1Pseudopodium-enriched atypical kinase 1. (1745 aa)
PKP2Plakophilin-2 isoform X1. (826 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (254 aa)
NPTNNeuroplastin isoform X1. (398 aa)
LOC111178591Cadherin-10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
PTPROReceptor-type tyrosine-protein phosphatase O isoform X1. (1216 aa)
DSTDystonin isoform X1. (7806 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
SRFSerum response factor isoform X2. (535 aa)
ADGRF1Adhesion G-protein coupled receptor F1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (912 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (475 aa)
LOC111178986LOW QUALITY PROTEIN: catenin alpha-1-like. (908 aa)
CTNND2Catenin delta-2 isoform X1. (1253 aa)
CDH9Cadherin-9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
GRID2Glutamate receptor ionotropic, delta-2 isoform X1. (1007 aa)
CDH18Cadherin-18 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
LRRC4Leucine-rich repeat-containing protein 4. (652 aa)
MPP7MAGUK p55 subfamily member 7 isoform X1; Belongs to the MAGUK family. (576 aa)
RHOCRho-related GTP-binding protein RhoC isoform X1. (242 aa)
NPHS1Nephrin. (1270 aa)
CDH12Cadherin-12 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
CDH20Cadherin-20; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
IGSF22Immunoglobulin superfamily member 22. (1325 aa)
HIPK1Homeodomain-interacting protein kinase 1 isoform X1. (1209 aa)
MARVELD3MARVEL domain-containing protein 3. (384 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa)
CDH7Cadherin-7 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (869 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
BCL2Apoptosis regulator Bcl-2. (233 aa)
LSRLipolysis-stimulated lipoprotein receptor isoform X3. (634 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
BCRBreakpoint cluster region protein isoform X1. (1275 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
CRKLCrk-like protein. (303 aa)
PLXND1plexin-D1. (1927 aa)
NLGN4XNeuroligin-4, X-linked isoform X1. (816 aa)
PCDH17Protocadherin-17 isoform X1. (1161 aa)
OPHN1Oligophrenin-1. (803 aa)
CLDN25LOW QUALITY PROTEIN: putative claudin-25. (230 aa)
OCEL1occludin/ELL domain-containing protein 1 isoform X1. (206 aa)
NLGN3Neuroligin-3 isoform X1. (848 aa)
CBLN2Cerebellin-2. (224 aa)
RCC2Protein RCC2 isoform X1. (543 aa)
ARVCFArmadillo repeat protein deleted in velo-cardio-facial syndrome isoform X1. (960 aa)
VMP1Vacuole membrane protein 1. (406 aa)
ACTN2Alpha-actinin-2. (894 aa)
JAM3Junctional adhesion molecule C. (301 aa)
FLCNFolliculin isoform X1. (591 aa)
ESAMLOW QUALITY PROTEIN: endothelial cell-selective adhesion molecule. (396 aa)
RAB13Ras-related protein Rab-13. (203 aa)
KIRREL3Kin of IRRE-like protein 3 isoform X1. (778 aa)
RAMP2Receptor activity-modifying protein 2. (177 aa)
PKN2Serine/threonine-protein kinase N2 isoform X1. (983 aa)
GJA10Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (492 aa)
AJUBALIM domain-containing protein ajuba isoform X1. (557 aa)
PTPRKReceptor-type tyrosine-protein phosphatase kappa isoform X1. (1485 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (236 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (680 aa)
CBLN1Cerebellin-1. (193 aa)
LOC111165064Plectin isoform X1. (4685 aa)
CDH24Cadherin-24 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (806 aa)
JUPJunction plakoglobin. (744 aa)
CDH11Cadherin-11 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
CDH8Cadherin-8 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (715 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2397 aa)
RHODRho-related GTP-binding protein RhoD. (210 aa)
LRRTM3Leucine-rich repeat transmembrane neuronal protein 3. (581 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
VCLVinculin isoform X2. (1134 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
SDK2Protein sidekick-2 isoform X1. (2172 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
LOC111182630Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
CTNNA1Catenin alpha-1. (906 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
FBF1Fas-binding factor 1 isoform X1. (1146 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
CDH19Cadherin-19 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (770 aa)
TAOK2Serine/threonine-protein kinase TAO2 isoform X1. (1234 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
TLN1Talin-1. (2541 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (525 aa)
CBLN4Cerebellin-4. (201 aa)
GABRB3Gamma-aminobutyric acid receptor subunit beta-3 isoform X2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
NR1H4Bile acid receptor isoform X1. (486 aa)
PARD6BPartitioning defective 6 homolog beta. (372 aa)
GABRG2Gamma-aminobutyric acid receptor subunit gamma-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
LOC111186242SH3 domain-binding protein 1 isoform X1. (693 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
SHANK3SH3 and multiple ankyrin repeat domains protein 3 isoform X1. (1733 aa)
PLXNB2plexin-B2. (1841 aa)
UGT82-hydroxyacylsphingosine 1-beta-galactosyltransferase; Belongs to the UDP-glycosyltransferase family. (541 aa)
NLGN2Neuroligin-2 isoform X1. (181 aa)
MARVELD2MARVEL domain-containing protein 2 isoform X2. (559 aa)
ASIC2Acid-sensing ion channel 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (512 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
LAMC1Laminin subunit gamma-1. (1608 aa)
GABRB2Gamma-aminobutyric acid receptor subunit beta-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
GABRA1Gamma-aminobutyric acid receptor subunit alpha-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
CLDN6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
DLG2Disks large homolog 2 isoform X1. (994 aa)
RAB29Ras-related protein Rab-7L1 isoform X1. (203 aa)
ARL2ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
MYPNMyopalladin. (1317 aa)
DLG5Disks large homolog 5 isoform X1; Belongs to the MAGUK family. (1980 aa)
DBNLDrebrin-like protein isoform X1. (430 aa)
SRCTyrosine-protein kinase. (562 aa)
NPAS4Neuronal PAS domain-containing protein 4. (798 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TBCDTubulin-specific chaperone D. (1197 aa)
ITGB4Integrin beta. (1826 aa)
CTNND1Catenin delta-1 isoform X1. (961 aa)
PECAM1Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
ACTN3Alpha-actinin-3 isoform X1. (902 aa)
HAPLN4Hyaluronan and proteoglycan link protein 4. (403 aa)
CTNNB1Catenin beta-1. (781 aa)
DCHS1Protocadherin-16. (3294 aa)
ADGRL3Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1549 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa)
CDH6Cadherin-6; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
PKP1Plakophilin-1 isoform X2. (727 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
ACTBActin, cytoplasmic 1. (375 aa)
ADD2Beta-adducin isoform X1. (836 aa)
LOC111171390LOW QUALITY PROTEIN: neuroligin-2-like. (304 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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