STRINGSTRING
RARB RARB CHD7 CHD7 TWIST1 TWIST1 ALX4 ALX4 FGF4 FGF4 WNT3 WNT3 PITX1 PITX1 OSR2 OSR2 ALX3 ALX3 NOTCH1 NOTCH1 SHH SHH TP63 TP63 FGF8 FGF8 RARG RARG BMP4 BMP4 MSX1 MSX1 CTNNB1 CTNNB1 ZBTB16 ZBTB16 MED1 MED1 GPC3 GPC3 RPGRIP1L RPGRIP1L TBX4 TBX4 TBX3 TBX3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RARBRetinoic acid receptor beta isoform X1. (448 aa)
CHD7chromodomain-helicase-DNA-binding protein 7 isoform X1. (3050 aa)
TWIST1Twist-related protein 1. (205 aa)
ALX4Homeobox protein aristaless-like 4. (406 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa)
PITX1Homeobox protein. (314 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
ALX3Homeobox protein aristaless-like 3. (343 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
RARGRetinoic acid receptor gamma isoform X1. (458 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (408 aa)
MSX1Homeobox protein MSX-1. (303 aa)
CTNNB1Catenin beta-1. (781 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16. (673 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
RPGRIP1LProtein fantom. (1269 aa)
TBX4T-box transcription factor TBX4. (555 aa)
TBX3T-box transcription factor TBX3 isoform X1. (745 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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