STRINGSTRING
IQGAP1 IQGAP1 HAS2 HAS2 FYN FYN PDGFRA PDGFRA SYAP1 SYAP1 HYAL1 HYAL1 MARS MARS PDGFRL PDGFRL LOC111176792 LOC111176792 MTSS1L MTSS1L ITGB3 ITGB3 CORO1B CORO1B PDGFRB PDGFRB SRC SRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1657 aa)
HAS2Hyaluronan synthase 2. (552 aa)
FYNTyrosine-protein kinase. (537 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
SYAP1Synapse-associated protein 1 isoform X1. (358 aa)
HYAL1Hyaluronidase. (448 aa)
MARSmethionine--tRNA ligase, cytoplasmic isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family. (900 aa)
PDGFRLPlatelet-derived growth factor receptor-like protein isoform X2. (375 aa)
LOC111176792LOW QUALITY PROTEIN: hyaluronan synthase 2-like. (318 aa)
MTSS1LMTSS1-like protein isoform X1. (750 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (640 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
SRCTyrosine-protein kinase. (562 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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