STRINGSTRING
BCL2 BCL2 ASNS ASNS PMAIP1 PMAIP1 SH3GLB1 SH3GLB1 SZT2 SZT2 SLC2A1 SLC2A1 HSPA5 HSPA5 PRKAA2 PRKAA2 PRKAG2 PRKAG2 ITFG2 ITFG2 ATG14 ATG14 IMPACT IMPACT KAT5 KAT5 TBL2 TBL2 SIRT1 SIRT1 ATF4 ATF4 NUAK2 NUAK2 MYBBP1A MYBBP1A PICK1 PICK1 EIF2AK3 EIF2AK3 NIM1K NIM1K PRKAA1 PRKAA1 NUAK1 NUAK1 BHLHA15 BHLHA15 KPTN KPTN SESN2 SESN2 SIK1 SIK1 XBP1 XBP1 FOXO3 FOXO3 MTMR3 MTMR3 SESN1 SESN1 PLIN3 PLIN3 SIK2 SIK2 BECN1 BECN1 PIK3C3 PIK3C3 RRP8 RRP8 SESN3 SESN3 SUV39H1 SUV39H1 PRKAG3 PRKAG3 CUNH12orf66 CUNH12orf66 ZC3H12A ZC3H12A NFE2L2 NFE2L2 PLIN2 PLIN2 PRKAG1 PRKAG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCL2Apoptosis regulator Bcl-2. (233 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing]. (561 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
SH3GLB1endophilin-B1 isoform X1. (365 aa)
SZT2LOW QUALITY PROTEIN: KICSTOR complex protein SZT2. (3440 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
HSPA578 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family. (655 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (566 aa)
ITFG2KICSTOR complex protein ITFG2 isoform X1. (450 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (492 aa)
IMPACTProtein IMPACT isoform X1. (318 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
TBL2Transducin beta-like protein 2. (446 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (735 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4 isoform X1. (350 aa)
NUAK2NUAK family SNF1-like kinase 2 isoform X1. (633 aa)
MYBBP1AMyb-binding protein 1A. (1407 aa)
PICK1PRKCA-binding protein isoform X1. (417 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1155 aa)
NIM1KSerine/threonine-protein kinase NIM1; Belongs to the protein kinase superfamily. (436 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
NUAK1NUAK family SNF1-like kinase 1 isoform X1. (666 aa)
BHLHA15Class A basic helix-loop-helix protein 15. (185 aa)
KPTNKICSTOR complex protein kaptin. (435 aa)
SESN2Sestrin-2. (471 aa)
SIK1Serine/threonine-protein kinase SIK1. (784 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa)
FOXO3Forkhead box protein O3. (672 aa)
MTMR3Myotubularin-related protein 3 isoform X1. (1202 aa)
SESN1Sestrin-1 isoform X1. (551 aa)
PLIN3Perilipin; Belongs to the perilipin family. (444 aa)
SIK2Serine/threonine-protein kinase SIK2 isoform X1. (912 aa)
BECN1Beclin-1 isoform X5. (471 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (482 aa)
SESN3Sestrin-3 isoform X1. (499 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (419 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (464 aa)
CUNH12orf66KICSTOR complex protein C12orf66 homolog. (445 aa)
ZC3H12AEndoribonuclease ZC3H12A. (583 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform X1. (622 aa)
PLIN2Perilipin; Belongs to the perilipin family. (455 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (330 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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