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| | CCL19 | C-C motif chemokine. (159 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (477 aa) |
| | AJUBA | LIM domain-containing protein ajuba isoform X1. (557 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | TRIB2 | Tribbles homolog 2. (343 aa) |
| | NOD2 | Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa) |
| | CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (562 aa) |
| | TPD52L1 | Tumor protein D53 isoform X1. (209 aa) |
| | TRIB1 | Tribbles homolog 1. (372 aa) |
| | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1392 aa) |
| | LOC111165935 | Ras-like protein isoform X1. (285 aa) |
| | CDK5RAP3 | CDK5 regulatory subunit-associated protein 3 isoform X1. (544 aa) |
| | LOC111166741 | SAM and SH3 domain-containing protein 1 isoform X1. (1513 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | GBA | Glucosylceramidase. (585 aa) |
| | LYN | Tyrosine-protein kinase. (518 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | SORL1 | Sortilin-related receptor isoform X1. (2211 aa) |
| | TGFA | Protransforming growth factor alpha isoform X1. (176 aa) |
| | PTPRC | Receptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 isoform X1. (1366 aa) |
| | CDK12 | Cyclin-dependent kinase 12 isoform X1. (1490 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (864 aa) |
| | PDGFA | Platelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (196 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (623 aa) |
| | DRD4 | D(4) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (521 aa) |
| | CD40 | Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4 isoform X1. (1601 aa) |
| | PDGFD | Platelet-derived growth factor D isoform X1. (402 aa) |
| | SYK | Tyrosine-protein kinase. (626 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1. (725 aa) |
| | SPRY3 | Protein sprouty homolog 3. (288 aa) |
| | AGER | Advanced glycosylation end product-specific receptor isoform X1. (631 aa) |
| | LOC111171273 | tenascin-X-like. (151 aa) |
| | RGS14 | Regulator of G-protein signaling 14 isoform X1. (604 aa) |
| | FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa) |
| | BMP4 | Bone morphogenetic protein 4 isoform X2. (408 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (308 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (929 aa) |
| | ADRA2A | alpha-2A adrenergic receptor. (465 aa) |
| | DUSP19 | Dual specificity protein phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (226 aa) |
| | LRRK2 | Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2527 aa) |
| | EPHA4 | Ephrin type-A receptor 4 isoform X1. (986 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (490 aa) |
| | DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa) |
| | ADAM8 | Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (823 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa) |
| | IRAK3 | Interleukin-1 receptor-associated kinase 3 isoform X2. (674 aa) |
| | FLT1 | Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa) |
| | PRKCD | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (733 aa) |
| | DVL3 | Segment polarity protein dishevelled homolog DVL-3 isoform X3. (731 aa) |
| | ADAM9 | Disintegrin and metalloproteinase domain-containing protein 9 isoform X1. (841 aa) |
| | PDCD10 | Programmed cell death protein 10. (212 aa) |
| | HYAL2 | Hyaluronidase. (476 aa) |
| | MST1R | Macrophage-stimulating protein receptor isoform X1. (1406 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa) |
| | SPRY2 | Protein sprouty homolog 2. (315 aa) |
| | DUSP16 | Dual specificity protein phosphatase 16. (660 aa) |
| | PDGFC | Platelet-derived growth factor C isoform X2. (380 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa) |
| | EZH2 | Histone-lysine N-methyltransferase EZH2 isoform X1. (747 aa) |
| | DAB2IP | Disabled homolog 2-interacting protein isoform X1. (1193 aa) |
| | ROBO1 | Roundabout homolog 1 isoform X1. (1685 aa) |
| | DUSP10 | Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | TSG101 | Tumor susceptibility gene 101 protein isoform X1. (429 aa) |
| | IL34 | Interleukin-34. (235 aa) |
| | FGD2 | FYVE, RhoGEF and PH domain-containing protein 2 isoform X1. (732 aa) |
| | TNFRSF11A | Tumor necrosis factor receptor superfamily member 11A isoform X1. (551 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | ERN2 | Serine/threonine-protein kinase/endoribonuclease IRE2. (927 aa) |
| | NUP62 | Nuclear pore glycoprotein p62. (516 aa) |
| | RASGRP1 | RAS guanyl-releasing protein 1 isoform X1. (870 aa) |
| | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1. (975 aa) |
| | MAP3K10 | Mitogen-activated protein kinase kinase kinase. (948 aa) |
| | DTNBP1 | Dysbindin isoform X1. (341 aa) |
| | EDN1 | Endothelin-1. (202 aa) |
| | LOC111182867 | CMRF35-like molecule 8 isoform X1. (313 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (368 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa) |
| | TMEM130 | Transmembrane protein 130 isoform X1. (435 aa) |
| | THBS1 | Thrombospondin-1. (1170 aa) |
| | MAP4K2 | Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa) |
| | SPRY4 | Protein sprouty homolog 4. (299 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa) |
| | LAX1 | LOW QUALITY PROTEIN: lymphocyte transmembrane adapter 1. (430 aa) |
| | RPS3 | 40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | TRIB3 | LOW QUALITY PROTEIN: tribbles homolog 3. (357 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase. (858 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (543 aa) |
| | NOX4 | NADPH oxidase 4. (530 aa) |
| | KSR1 | Kinase suppressor of Ras 1 isoform X1. (905 aa) |
| | FZD4 | Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | AXIN1 | Axin-1 isoform X1. (866 aa) |
| | INPP5K | Inositol polyphosphate 5-phosphatase K isoform X1. (476 aa) |
| | HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (884 aa) |
| | PDGFB | Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (278 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | SPRY1 | Protein sprouty homolog 1. (319 aa) |
| | SH2B3 | SH2B adapter protein 3 isoform X1. (618 aa) |
| | DUSP1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | DVL2 | LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2. (736 aa) |
| | NF1 | Neurofibromin isoform X1. (2873 aa) |
| | TAOK3 | Serine/threonine-protein kinase TAO3. (898 aa) |
| | FZD10 | Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | PIK3R5 | Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (871 aa) |
| | PIK3R6 | Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa) |
| | EPGN | Epigen. (153 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (451 aa) |
| | PAQR3 | Progestin and adipoQ receptor family member 3 isoform X1. (311 aa) |
| | SFRP2 | Secreted frizzled-related protein 2. (294 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
