STRINGSTRING
ITGB1BP1 ITGB1BP1 JUP JUP TBXA2R TBXA2R MMRN2 MMRN2 HDAC5 HDAC5 MECP2 MECP2 LOC111170713 LOC111170713 VASH1 VASH1 ANGPT2 ANGPT2 RHOA RHOA ACVRL1 ACVRL1 PDCD10 PDCD10 STARD13 STARD13 GADD45A GADD45A NOTCH1 NOTCH1 TGFB1 TGFB1 DLL4 DLL4 SPRED1 SPRED1 MEOX2 MEOX2 THBS1 THBS1 ANGPT4 ANGPT4 MEF2C MEF2C ATP2B4 ATP2B4 LOC111186398 LOC111186398 TNF TNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (206 aa)
JUPJunction plakoglobin. (744 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
MMRN2Multimerin-2 isoform X1. (935 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1123 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (486 aa)
LOC111170713Lymphocyte antigen 6 complex locus protein G5b isoform X2. (299 aa)
VASH1Vasohibin-1 isoform X1. (387 aa)
ANGPT2Angiopoietin-2 isoform X1. (496 aa)
RHOATransforming protein RhoA. (193 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
PDCD10Programmed cell death protein 10. (212 aa)
STARD13stAR-related lipid transfer protein 13 isoform X1. (1126 aa)
GADD45AGrowth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
SPRED1Sprouty-related, EVH1 domain-containing protein 1 isoform X1. (445 aa)
MEOX2Homeobox protein MOX-2. (303 aa)
THBS1Thrombospondin-1. (1170 aa)
ANGPT4Angiopoietin-4. (498 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X6. (483 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
LOC111186398Caspase recruitment domain-containing protein 10 isoform X1. (1027 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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