STRINGSTRING
FLT1 FLT1 SOCS1 SOCS1 EPHA8 EPHA8 FGR FGR CCL19 CCL19 SLA2 SLA2 TGFB1 TGFB1 VAV3 VAV3 WDR91 WDR91 DAB2IP DAB2IP VAV2 VAV2 CISH CISH PIK3R3 PIK3R3 ATG14 ATG14 SOCS2 SOCS2 PIK3R6 PIK3R6 PIK3R5 PIK3R5 PIK3R1 PIK3R1 WDR81 WDR81 PTK2B PTK2B PDGFB PDGFB CD19 CD19 SOCS6 SOCS6 SOCS3 SOCS3 PDGFRB PDGFRB AMBRA1 AMBRA1 SOCS5 SOCS5 RUBCN RUBCN SOCS4 SOCS4 PDGFRA PDGFRA PIK3R4 PIK3R4 SOCS7 SOCS7 LYN LYN PIK3R2 PIK3R2 FGFR3 FGFR3 TEK TEK NOD2 NOD2 PIK3IP1 PIK3IP1 CCL21 CCL21
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
EPHA8Ephrin type-A receptor 8. (1005 aa)
FGRTyrosine-protein kinase. (526 aa)
CCL19C-C motif chemokine. (159 aa)
SLA2Src-like-adapter 2 isoform X1. (276 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
VAV3Guanine nucleotide exchange factor VAV3. (954 aa)
WDR91WD repeat-containing protein 91 isoform X1. (746 aa)
DAB2IPDisabled homolog 2-interacting protein isoform X1. (1193 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
CISHCytokine-inducible SH2-containing protein isoform X1. (254 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (492 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
PIK3R6Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa)
PIK3R5Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (871 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
WDR81WD repeat-containing protein 81. (1944 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (278 aa)
CD19B-lymphocyte antigen CD19 isoform X1. (570 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
SOCS3Suppressor of cytokine signaling 3. (237 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1295 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
RUBCNRun domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1. (1007 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
SOCS7Suppressor of cytokine signaling 7 isoform X1. (641 aa)
LYNTyrosine-protein kinase. (518 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
FGFR3Fibroblast growth factor receptor. (805 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa)
PIK3IP1Phosphoinositide-3-kinase-interacting protein 1 isoform X1. (264 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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