STRINGSTRING
PDGFB PDGFB CCL19 CCL19 FGR FGR EPHA8 EPHA8 CCL21 CCL21 NOD2 NOD2 TEK TEK FGFR3 FGFR3 LYN LYN VAV2 VAV2 ATG14 ATG14 FLT1 FLT1 PDGFRA PDGFRA PIK3R4 PIK3R4 VAV3 VAV3 PTK2B PTK2B TGFB1 TGFB1 CD19 CD19 PDGFRB PDGFRB AMBRA1 AMBRA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (278 aa)
CCL19C-C motif chemokine. (159 aa)
FGRTyrosine-protein kinase. (526 aa)
EPHA8Ephrin type-A receptor 8. (1005 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
FGFR3Fibroblast growth factor receptor. (805 aa)
LYNTyrosine-protein kinase. (518 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (492 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
VAV3Guanine nucleotide exchange factor VAV3. (954 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
CD19B-lymphocyte antigen CD19 isoform X1. (570 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1295 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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