8 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INSR	Tyrosine-protein kinase receptor. (1392 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1368 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (733 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	DCAF8	DDB1- and CUL4-associated factor 8. (596 aa)
	INSRR	Tyrosine-protein kinase receptor. (1301 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRB2	IGF1R	A0A2Y9PJ90	A0A2Y9QAK7	Growth factor receptor-bound protein 2.	Tyrosine-protein kinase receptor.	0.972
GRB2	INSR	A0A2Y9PJ90	A0A2Y9LSN6	Growth factor receptor-bound protein 2.	Tyrosine-protein kinase receptor.	0.967
GRB2	INSRR	A0A2Y9PJ90	A0A2Y9LZU1	Growth factor receptor-bound protein 2.	Tyrosine-protein kinase receptor.	0.948
GRB2	PIK3CA	A0A2Y9PJ90	A0A2Y9MZW2	Growth factor receptor-bound protein 2.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.665
GRB2	PIK3R1	A0A2Y9PJ90	A0A2Y9Q8T5	Growth factor receptor-bound protein 2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.940
IGF1R	GRB2	A0A2Y9QAK7	A0A2Y9PJ90	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 2.	0.972
IGF1R	INSR	A0A2Y9QAK7	A0A2Y9LSN6	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.981
IGF1R	INSRR	A0A2Y9QAK7	A0A2Y9LZU1	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.604
IGF1R	PIK3CA	A0A2Y9QAK7	A0A2Y9MZW2	Tyrosine-protein kinase receptor.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.965
IGF1R	PIK3R1	A0A2Y9QAK7	A0A2Y9Q8T5	Tyrosine-protein kinase receptor.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.970
INSR	GRB2	A0A2Y9LSN6	A0A2Y9PJ90	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 2.	0.967
INSR	IGF1R	A0A2Y9LSN6	A0A2Y9QAK7	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.981
INSR	INSRR	A0A2Y9LSN6	A0A2Y9LZU1	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.756
INSR	PIK3CA	A0A2Y9LSN6	A0A2Y9MZW2	Tyrosine-protein kinase receptor.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.928
INSR	PIK3R1	A0A2Y9LSN6	A0A2Y9Q8T5	Tyrosine-protein kinase receptor.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.917
INSRR	GRB2	A0A2Y9LZU1	A0A2Y9PJ90	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 2.	0.948
INSRR	IGF1R	A0A2Y9LZU1	A0A2Y9QAK7	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.604
INSRR	INSR	A0A2Y9LZU1	A0A2Y9LSN6	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.756
INSRR	PIK3CA	A0A2Y9LZU1	A0A2Y9MZW2	Tyrosine-protein kinase receptor.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.749
INSRR	PIK3R1	A0A2Y9LZU1	A0A2Y9Q8T5	Tyrosine-protein kinase receptor.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.818