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UGP2 UGP2 B3GNT8 B3GNT8 LOC111182058 LOC111182058 PPIP5K1 PPIP5K1 GALK2 GALK2 AGL AGL NHLRC1 NHLRC1 GUSB GUSB LOC111181112 LOC111181112 GANC GANC GSK3A GSK3A GYS1 GYS1 AOAH AOAH LOC111186101 LOC111186101 INPP5K INPP5K EXT2 EXT2 PYGB PYGB NDST2 NDST2 GNPTG GNPTG GCK GCK NDST1 NDST1 GALK1 GALK1 PFKFB2 PFKFB2 INPP5B INPP5B SHPK SHPK PLA2G4A PLA2G4A NDST3 NDST3 PGP PGP MIOX MIOX PFKL PFKL IL6ST IL6ST B4GALT5 B4GALT5 B3GNT4 B3GNT4 PPP1CC PPP1CC SLC37A4 SLC37A4 GK GK NAGK NAGK OCRL OCRL EPM2A EPM2A B3GNT3 B3GNT3 SYNJ2 SYNJ2 IMPA1 IMPA1 FBP2 FBP2 IDNK IDNK ISYNA1 ISYNA1 NR1D1 NR1D1 G6PC G6PC COQ3 COQ3 PFKP PFKP RB1CC1 RB1CC1 IMPAD1 IMPAD1 EXT1 EXT1 XYLB XYLB SYNJ1 SYNJ1 PHKB PHKB HAS2 HAS2 EPM2AIP1 EPM2AIP1 PCK2 PCK2 FUT9 FUT9 INPP5J INPP5J B4GALT1 B4GALT1 IMPA2 IMPA2 FUK FUK ACADM ACADM B3GNT9 B3GNT9 HS2ST1 HS2ST1 GYG1 GYG1 BPNT1 BPNT1 GK5 GK5 HAS3 HAS3 LOC111176792 LOC111176792 PFKFB3 PFKFB3 LEPR LEPR INPP5E INPP5E BRAF BRAF FGGY FGGY GYS2 GYS2 ANGPTL3 ANGPTL3 PRKAG2 PRKAG2 STK40 STK40 SI SI ITPK1 ITPK1 KHK KHK TPI1 TPI1 PPP1CB PPP1CB PFKFB1 PFKFB1 HK2 HK2 HK3 HK3 GSK3B GSK3B PHKA1 PHKA1 PGM2 PGM2 PHKA2 PHKA2 GYG2 GYG2 MECP2 MECP2 MTMR2 MTMR2 IDH2 IDH2 INPP1 INPP1 IPPK IPPK B3GNT7 B3GNT7 POMK POMK RBKS RBKS PFKFB4 PFKFB4 IDH1 IDH1 PFKM PFKM GOT1 GOT1 LALBA LALBA PRKAG3 PRKAG3 PPP1R3B PPP1R3B GPD2 GPD2 LCT LCT PPP1R3C PPP1R3C PYGL PYGL NEU2 NEU2 MOGAT1 MOGAT1 GAA GAA RPE RPE INPP5A INPP5A LOC111172100 LOC111172100 B3GNT2 B3GNT2 GK2 GK2 PCK1 PCK1 PPP1R3D PPP1R3D GNPTAB GNPTAB LOC111187139 LOC111187139 PGD PGD ABHD10 ABHD10 STBD1 STBD1 LOC111187721 LOC111187721 GNE GNE PYGM PYGM PHKG2 PHKG2 HK1 HK1 HKDC1 HKDC1 PPIP5K2 PPIP5K2 TKFC TKFC PHKG1 PHKG1 ITPKA ITPKA SORD SORD LOC111183111 LOC111183111 PPP1CA PPP1CA PCDH12 PCDH12 ENOSF1 ENOSF1 HAS1 HAS1 LOC111182490 LOC111182490
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UGP2UTP--glucose-1-phosphate uridylyltransferase. (536 aa)
B3GNT8Hexosyltransferase. (397 aa)
LOC111182058General transcription factor II-I repeat domain-containing protein 2 isoform X1. (948 aa)
PPIP5K1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1594 aa)
GALK2N-acetylgalactosamine kinase isoform X1. (482 aa)
AGLGlycogen debranching enzyme. (1532 aa)
NHLRC1E3 ubiquitin-protein ligase NHLRC1. (395 aa)
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (652 aa)
LOC111181112Uncharacterized protein LOC111181112. (257 aa)
GANCNeutral alpha-glucosidase C isoform X1; Belongs to the glycosyl hydrolase 31 family. (913 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
AOAHAcyloxyacyl hydrolase isoform X1. (671 aa)
LOC111186101Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 isoform X1. (872 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform X1. (476 aa)
EXT2Exostosin-2 isoform X1; Belongs to the glycosyltransferase 47 family. (718 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
NDST2Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2. (883 aa)
GNPTGN-acetylglucosamine-1-phosphotransferase subunit gamma. (306 aa)
GCKPhosphotransferase. (537 aa)
NDST1Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 isoform X1. (882 aa)
GALK1Galactokinase isoform X1. (459 aa)
PFKFB26-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 isoform X1. (554 aa)
INPP5BType II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1. (994 aa)
SHPKSedoheptulokinase. (478 aa)
PLA2G4APhospholipase A2. (749 aa)
NDST3Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 isoform X1. (887 aa)
PGPGlycerol-3-phosphate phosphatase; Belongs to the HAD-like hydrolase superfamily. (321 aa)
MIOXInositol oxygenase. (269 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
IL6STInterleukin-6 receptor subunit beta. (918 aa)
B4GALT5Beta-1,4-galactosyltransferase 5 isoform X1. (388 aa)
B3GNT4Hexosyltransferase. (357 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
SLC37A4Glucose-6-phosphate exchanger SLC37A4 isoform X1. (429 aa)
GKGlycerol kinase isoform X1; Belongs to the FGGY kinase family. (581 aa)
NAGKN-acetyl-D-glucosamine kinase isoform X2. (344 aa)
OCRLInositol polyphosphate 5-phosphatase OCRL-1 isoform X1. (893 aa)
EPM2ALaforin isoform X1. (331 aa)
B3GNT3Hexosyltransferase. (369 aa)
SYNJ2Synaptojanin-2 isoform X1. (1478 aa)
IMPA1Inositol-1-monophosphatase. (277 aa)
FBP2Fructose-1,6-bisphosphatase isozyme 2; Belongs to the FBPase class 1 family. (339 aa)
IDNKGluconokinase; Belongs to the gluconokinase GntK/GntV family. (185 aa)
ISYNA1Inositol-3-phosphate synthase 1. (557 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (371 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (809 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform X1. (1589 aa)
IMPAD1Inositol monophosphatase 3. (359 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
XYLBXylulose kinase isoform X1. (583 aa)
SYNJ1Synaptojanin-1 isoform X2. (1592 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1090 aa)
HAS2Hyaluronan synthase 2. (552 aa)
EPM2AIP1EPM2A-interacting protein 1. (608 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (655 aa)
FUT9Alpha-(1,3)-fucosyltransferase 9 isoform X1. (368 aa)
INPP5JPhosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1. (980 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (402 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
FUKL-fucose kinase isoform X1. (1083 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial. (421 aa)
B3GNT9Hexosyltransferase. (402 aa)
HS2ST1Heparan sulfate 2-O-sulfotransferase 1 isoform X1. (357 aa)
GYG1Glycogenin-1. (393 aa)
BPNT13'(2'),5'-bisphosphate nucleotidase 1. (308 aa)
GK5Putative glycerol kinase 5 isoform X1; Belongs to the FGGY kinase family. (547 aa)
HAS3Hyaluronan synthase 3. (553 aa)
LOC111176792LOW QUALITY PROTEIN: hyaluronan synthase 2-like. (318 aa)
PFKFB36-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X1. (526 aa)
LEPRLeptin receptor isoform X1. (917 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (627 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X1. (762 aa)
FGGYFGGY carbohydrate kinase domain-containing protein isoform X1. (583 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (702 aa)
ANGPTL3Angiopoietin-related protein 3. (460 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (566 aa)
STK40Serine/threonine-protein kinase 40 isoform X1. (435 aa)
SISucrase-isomaltase, intestinal. (1825 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase isoform X1. (419 aa)
KHKKetohexokinase isoform X1. (298 aa)
TPI1Triosephosphate isomerase. (286 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1. (471 aa)
HK2Hexokinase-2. (917 aa)
HK3Hexokinase-3 isoform X1. (924 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1226 aa)
PGM2Phosphoglucomutase-2. (616 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1217 aa)
GYG2Glycogenin-2 isoform X1. (466 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (486 aa)
MTMR2Myotubularin-related protein 2 isoform X1. (643 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
INPP1Inositol polyphosphate 1-phosphatase. (402 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (547 aa)
B3GNT7Hexosyltransferase. (469 aa)
POMKProtein O-mannose kinase. (350 aa)
RBKSRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (326 aa)
PFKFB46-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 4 isoform X1. (520 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
GOT1Aspartate aminotransferase. (413 aa)
LALBAAlpha-lactalbumin; Belongs to the glycosyl hydrolase 22 family. (141 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (464 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (366 aa)
GPD2Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (746 aa)
LCTLactase-phlorizin hydrolase. (1928 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (854 aa)
NEU2LOW QUALITY PROTEIN: sialidase-2. (407 aa)
MOGAT12-acylglycerol O-acyltransferase 1. (419 aa)
GAALysosomal alpha-glucosidase isoform X1; Belongs to the glycosyl hydrolase 31 family. (943 aa)
RPERibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (239 aa)
INPP5AType I inositol 1,4,5-trisphosphate 5-phosphatase isoform X1. (534 aa)
LOC111172100Glycerol kinase-like; Belongs to the FGGY kinase family. (522 aa)
B3GNT2Hexosyltransferase. (397 aa)
GK2LOW QUALITY PROTEIN: glycerol kinase 2. (552 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1. (687 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit. (298 aa)
GNPTABN-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X1. (1257 aa)
LOC1111871396-phosphogluconate dehydrogenase, decarboxylating-like isoform X1. (152 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
ABHD10Mycophenolic acid acyl-glucuronide esterase, mitochondrial. (303 aa)
STBD1Starch-binding domain-containing protein 1. (356 aa)
LOC111187721Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
GNEBifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase. (722 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
PHKG2Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; Belongs to the protein kinase superfamily. (406 aa)
HK1Hexokinase-1 isoform X2. (935 aa)
HKDC1Putative hexokinase HKDC1 isoform X1. (918 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1243 aa)
TKFCtriokinase/FMN cyclase isoform X1. (577 aa)
PHKG1Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Belongs to the protein kinase superfamily. (387 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (460 aa)
SORDSorbitol dehydrogenase isoform X1. (356 aa)
LOC111183111Hexosyltransferase. (395 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
PCDH12LOW QUALITY PROTEIN: protocadherin-12. (1199 aa)
ENOSF1Mitochondrial enolase superfamily member 1 isoform X1. (443 aa)
HAS1Hyaluronan synthase 1. (582 aa)
LOC111182490LOW QUALITY PROTEIN: ribulose-phosphate 3-epimerase-like. (327 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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