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TMEM65 TMEM65 FGFRL1 FGFRL1 JUP JUP ATP1B1 ATP1B1 GJA1 GJA1 FLCN FLCN JAM3 JAM3 SCN4B SCN4B CTNNB1 CTNNB1 SCN5A SCN5A RAP2C RAP2C DES DES OPALIN OPALIN FLOT1 FLOT1 SCN1A SCN1A ACTN1 ACTN1 PIK3CA PIK3CA PGM5 PGM5 NRAP NRAP JAM2 JAM2 CXADR CXADR PKP4 PKP4 PCDH9 PCDH9 KCNA5 KCNA5 RAP2A RAP2A TJP2 TJP2 PKP2 PKP2 LOC111178986 LOC111178986 SLC31A1 SLC31A1 GJA5 GJA5 ITGB1 ITGB1 RAP2B RAP2B CADM4 CADM4 FHOD1 FHOD1 NECTIN2 NECTIN2 SCN1B SCN1B SPTBN4 SPTBN4 FXYD1 FXYD1 DSP DSP DSG2 DSG2 CTNNA1 CTNNA1 CDH2 CDH2 CTNNA3 CTNNA3 VCL VCL FLOT2 FLOT2 RANGRF RANGRF AJAP1 AJAP1 BAIAP2L2 BAIAP2L2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMEM65Transmembrane protein 65 isoform X1. (243 aa)
FGFRL1Fibroblast growth factor receptor-like 1 isoform X1. (503 aa)
JUPJunction plakoglobin. (744 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
FLCNFolliculin isoform X1. (591 aa)
JAM3Junctional adhesion molecule C. (301 aa)
SCN4BSodium channel subunit beta-4 isoform X1. (248 aa)
CTNNB1Catenin beta-1. (781 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
RAP2CRas-related protein Rap-2c. (183 aa)
DESDesmin; Belongs to the intermediate filament family. (470 aa)
OPALINOpalin isoform X1. (150 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
ACTN1Alpha-actinin-1 isoform X2. (914 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PGM5Phosphoglucomutase-like protein 5 isoform X1; Belongs to the phosphohexose mutase family. (567 aa)
NRAPNebulin-related-anchoring protein. (1608 aa)
JAM2Junctional adhesion molecule B isoform X1. (350 aa)
CXADRCoxsackievirus and adenovirus receptor isoform X1. (365 aa)
PKP4Plakophilin-4 isoform X1. (1193 aa)
PCDH9Protocadherin-9 isoform X1. (1203 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (597 aa)
RAP2ARas-related protein Rap-2a. (183 aa)
TJP2Tight junction protein ZO-2 isoform X2; Belongs to the MAGUK family. (1187 aa)
PKP2Plakophilin-2 isoform X1. (826 aa)
LOC111178986LOW QUALITY PROTEIN: catenin alpha-1-like. (908 aa)
SLC31A1High affinity copper uptake protein 1. (191 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
RAP2BRas-related protein Rap-2b. (183 aa)
CADM4Cell adhesion molecule 4. (388 aa)
FHOD1FH1/FH2 domain-containing protein 1 isoform X1. (1195 aa)
NECTIN2Nectin-2 isoform X1. (539 aa)
SCN1BSodium channel subunit beta-1 isoform X1. (218 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2560 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
DSPDesmoplakin isoform X1. (2874 aa)
DSG2Desmoglein-2. (1116 aa)
CTNNA1Catenin alpha-1. (906 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
CTNNA3Catenin alpha-3. (944 aa)
VCLVinculin isoform X2. (1134 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
RANGRFRan guanine nucleotide release factor isoform X1. (186 aa)
AJAP1Adherens junction-associated protein 1. (410 aa)
BAIAP2L2Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 isoform X1. (558 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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