STRINGSTRING
SMARCB1 SMARCB1 ARID1A ARID1A HP1BP3 HP1BP3 LOC111164170 LOC111164170 NDC80 NDC80 REC8 REC8 NEFH NEFH RAD21 RAD21 TOP3B TOP3B TINF2 TINF2 SMARCA4 SMARCA4 LOC111166433 LOC111166433 SMARCE1 SMARCE1 MPND MPND NCAPD3 NCAPD3 SHPRH SHPRH MBTD1 MBTD1 PHF10 PHF10 SPC24 SPC24 LOC111168444 LOC111168444 LOC111168449 LOC111168449 LOC111168519 LOC111168519 LOC111168524 LOC111168524 LOC111168528 LOC111168528 STAG2 STAG2 LOC111168549 LOC111168549 LOC111168445 LOC111168445 LOC111168506 LOC111168506 LOC111168515 LOC111168515 LOC111168520 LOC111168520 LOC111168525 LOC111168525 LOC111168529 LOC111168529 ASH1L ASH1L LOC111168828 LOC111168828 ARID1B ARID1B LOC111168503 LOC111168503 LOC111168512 LOC111168512 LOC111168516 LOC111168516 LOC111168521 LOC111168521 LOC111168526 LOC111168526 LOC111168530 LOC111168530 LOC111168978 LOC111168978 LOC111169737 LOC111169737 NUF2 NUF2 LOC111169749 LOC111169749 LOC111167415 LOC111167415 LOC111168446 LOC111168446 LOC111168460 LOC111168460 VPS72 VPS72 LOC111168504 LOC111168504 LOC111168507 LOC111168507 LOC111168517 LOC111168517 LOC111168527 LOC111168527 LOC111168531 LOC111168531 LOC111168543 LOC111168543 LOC111167944 LOC111167944 LOC111169314 LOC111169314 LOC111171291 LOC111171291 LOC111168439 LOC111168439 LOC111168443 LOC111168443 LOC111168448 LOC111168448 LOC111169704 LOC111169704 LOC111168505 LOC111168505 LOC111168508 LOC111168508 LOC111168514 LOC111168514 LOC111168523 LOC111168523 LOC111168536 LOC111168536 LOC111168544 LOC111168544 LOC111168550 LOC111168550 LOC111169747 LOC111169747 SGO2 SGO2 RUVBL1 RUVBL1 LOC111171120 LOC111171120 LOC111171154 LOC111171154 TNP1 TNP1 LOC111169315 LOC111169315 MORF4L2 MORF4L2 LOC111169736 LOC111169736 LOC111169748 LOC111169748 SMC1A SMC1A LOC111171155 LOC111171155 DPF3 DPF3 SMC3 SMC3 NCAPG NCAPG STN1 STN1 EPC2 EPC2 ACTL6A ACTL6A KAT6A KAT6A PRM3 PRM3 SPC25 SPC25 SMARCA2 SMARCA2 YEATS4 YEATS4 SMARCC1 SMARCC1 SMARCD1 SMARCD1 ARID2 ARID2 PBRM1 PBRM1 SMC4 SMC4 NCAPG2 NCAPG2 MEAF6 MEAF6 LOC111176743 LOC111176743 LOC111176794 LOC111176794 BCL11B BCL11B NCAPD2 NCAPD2 SMARCD3 SMARCD3 CENPA CENPA EPC1 EPC1 BRD9 BRD9 DMAP1 DMAP1 POT1 POT1 ING3 ING3 TERB1 TERB1 TERF2IP TERF2IP ACD ACD LOC111179105 LOC111179105 STAG1 STAG1 TERF2 TERF2 BICRA BICRA IRF4 IRF4 DPF1 DPF1 STAG3 STAG3 LOC111182487 LOC111182487 BCL7B BCL7B RUVBL2 RUVBL2 SPHK2 SPHK2 LOC111182462 LOC111182462 LOC111182488 LOC111182488 SS18 SS18 TEN1 TEN1 LOC111183465 LOC111183465 KAT5 KAT5 KAT6B KAT6B ACTL6B ACTL6B BCL7C BCL7C SLF1 SLF1 SMARCD2 SMARCD2 LOC111184525 LOC111184525 LOC111182816 LOC111182816 DPF2 DPF2 GLYR1 GLYR1 RAD21L1 RAD21L1 CTC1 CTC1 TERF1 TERF1 MRGBP MRGBP BCL7A BCL7A NCAPH2 NCAPH2 SMC1B SMC1B NCAPH NCAPH LOC111186403 LOC111186403 BCL11A BCL11A SMC2 SMC2 EP400 EP400
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
ARID1AAT-rich interactive domain-containing protein 1A isoform X1. (2287 aa)
HP1BP3Heterochromatin protein 1-binding protein 3 isoform X1. (553 aa)
LOC111164170Histone H3.3-like. (182 aa)
NDC80Kinetochore protein NDC80 homolog. (642 aa)
REC8Meiotic recombination protein REC8 homolog isoform X1. (584 aa)
NEFHNeurofilament heavy polypeptide isoform X2; Belongs to the intermediate filament family. (899 aa)
RAD21Double-strand-break repair protein rad21 homolog. (630 aa)
TOP3BDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (861 aa)
TINF2TERF1-interacting nuclear factor 2 isoform X1. (477 aa)
SMARCA4Transcription activator BRG1 isoform X4. (1648 aa)
LOC111166433Spermatid-specific linker histone H1-like protein. (175 aa)
SMARCE1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1. (411 aa)
MPNDMPN domain-containing protein. (491 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1510 aa)
SHPRHE3 ubiquitin-protein ligase SHPRH isoform X1. (1685 aa)
MBTD1MBT domain-containing protein 1 isoform X1. (654 aa)
PHF10PHD finger protein 10 isoform X1. (498 aa)
SPC24Kinetochore protein Spc24. (197 aa)
LOC111168444Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC111168449Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168519Histone H2A; Belongs to the histone H2A family. (131 aa)
LOC111168524Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168528Histone H2B; Belongs to the histone H2B family. (126 aa)
STAG2Cohesin subunit SA-2 isoform X1. (1268 aa)
LOC111168549Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC111168445Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168506Histone H1.1. (197 aa)
LOC111168515Histone H3; Belongs to the histone H3 family. (136 aa)
LOC111168520Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC111168525Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168529Histone H2B; Belongs to the histone H2B family. (126 aa)
ASH1LHistone-lysine N-methyltransferase ASH1L isoform X1. (2964 aa)
LOC111168828Histone H1x. (213 aa)
ARID1BAT-rich interactive domain-containing protein 1B isoform X1. (2373 aa)
LOC111168503Histone H1t. (226 aa)
LOC111168512Histone H2A; Belongs to the histone H2A family. (153 aa)
LOC111168516Histone H3; Belongs to the histone H3 family. (136 aa)
LOC111168521Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC111168526Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168530Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168978Histone H1oo. (319 aa)
LOC111169737Histone H3; Belongs to the histone H3 family. (136 aa)
NUF2Kinetochore protein Nuf2. (464 aa)
LOC111169749Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111167415Histone H2A; Belongs to the histone H2A family. (143 aa)
LOC111168446Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168460Histone H2B; Belongs to the histone H2B family. (127 aa)
VPS72Vacuolar protein sorting-associated protein 72 homolog. (364 aa)
LOC111168504Histone H1.3. (221 aa)
LOC111168507Histone H1.2. (213 aa)
LOC111168517Histone H2A; Belongs to the histone H2A family. (134 aa)
LOC111168527Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168531Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (112 aa)
LOC111168543Uncharacterized protein LOC111168543; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (333 aa)
LOC111167944Histone H3.3-like. (136 aa)
LOC111169314Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC111171291Histone H3; Belongs to the histone H3 family. (125 aa)
LOC111168439Histone H1.5. (226 aa)
LOC111168443Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC111168448Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111169704Histone H3.3-like. (136 aa)
LOC111168505Histone H1.4. (219 aa)
LOC111168508Histone H1.4-like. (211 aa)
LOC111168514Histone H2A; Belongs to the histone H2A family. (139 aa)
LOC111168523Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168536Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC111168544Histone H2B type 1-L-like; Belongs to the histone H2B family. (143 aa)
LOC111168550Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC111169747Histone H2A; Belongs to the histone H2A family. (130 aa)
SGO2Shugoshin 2. (1345 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
LOC111171120Late histone H2B.L4-like; Belongs to the histone H2B family. (135 aa)
LOC111171154Histone H2A; Belongs to the histone H2A family. (130 aa)
TNP1Spermatid nuclear transition protein 1. (55 aa)
LOC111169315Histone H2B; Belongs to the histone H2B family. (126 aa)
MORF4L2Mortality factor 4-like protein 2. (288 aa)
LOC111169736Histone H2B; Belongs to the histone H2B family. (197 aa)
LOC111169748Histone H2A; Belongs to the histone H2A family. (129 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
LOC111171155Histone H2B; Belongs to the histone H2B family. (126 aa)
DPF3Zinc finger protein DPF3. (378 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
NCAPGCondensin complex subunit 3. (1009 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (394 aa)
EPC2Enhancer of polycomb homolog. (807 aa)
ACTL6AActin-like protein 6A; Belongs to the actin family. (429 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2027 aa)
PRM3Protamine-3. (86 aa)
SPC25Kinetochore protein Spc25. (226 aa)
SMARCA2Probable global transcription activator SNF2L2 isoform X1. (1597 aa)
YEATS4YEATS domain-containing protein 4. (227 aa)
SMARCC1SWI/SNF complex subunit SMARCC1 isoform X1. (1105 aa)
SMARCD1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1. (515 aa)
ARID2AT-rich interactive domain-containing protein 2. (1836 aa)
PBRM1Protein polybromo-1 isoform X1. (1725 aa)
SMC4Structural maintenance of chromosomes protein. (1288 aa)
NCAPG2Condensin-2 complex subunit G2 isoform X1. (1140 aa)
MEAF6Chromatin modification-related protein MEAF6 isoform X1. (201 aa)
LOC111176743Histone H2B; Belongs to the histone H2B family. (122 aa)
LOC111176794Histone H2A; Belongs to the histone H2A family. (129 aa)
BCL11BB-cell lymphoma/leukemia 11B isoform X1. (903 aa)
NCAPD2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1400 aa)
SMARCD3SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D. (483 aa)
CENPAHistone H3-like centromeric protein A. (138 aa)
EPC1Enhancer of polycomb homolog. (842 aa)
BRD9Bromodomain-containing protein 9 isoform X1. (738 aa)
DMAP1DNA methyltransferase 1-associated protein 1 isoform X1. (468 aa)
POT1Protection of telomeres protein 1 isoform X1. (796 aa)
ING3Inhibitor of growth protein. (418 aa)
TERB1Telomere repeats-binding bouquet formation protein 1. (732 aa)
TERF2IPTelomeric repeat-binding factor 2-interacting protein 1. (398 aa)
ACDAdrenocortical dysplasia protein homolog isoform X1. (454 aa)
LOC111179105Histone H2A; Belongs to the histone H2A family. (128 aa)
STAG1Cohesin subunit SA-1 isoform X1. (1258 aa)
TERF2Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (539 aa)
BICRABRD4-interacting chromatin-remodeling complex-associated protein isoform X1. (1573 aa)
IRF4Interferon regulatory factor 4 isoform X1. (451 aa)
DPF1Zinc finger protein neuro-d4 isoform X1. (427 aa)
STAG3Cohesin subunit SA-3. (1248 aa)
LOC111182487Bromodomain-containing protein 8 isoform X1. (951 aa)
BCL7BB-cell CLL/lymphoma 7 protein family member B isoform X1. (202 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
SPHK2Sphingosine kinase 2 isoform X1. (655 aa)
LOC111182462Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
LOC111182488Bromodomain-containing protein 8-like. (364 aa)
SS18Protein SSXT isoform X1. (418 aa)
TEN1CST complex subunit TEN1 isoform X1. (123 aa)
LOC111183465Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2055 aa)
ACTL6BActin-like protein 6B isoform X1; Belongs to the actin family. (476 aa)
BCL7CB-cell CLL/lymphoma 7 protein family member C isoform X1. (217 aa)
SLF1SMC5-SMC6 complex localization factor protein 1. (1057 aa)
SMARCD2SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D. (636 aa)
LOC111184525Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC111182816Histone H3; Belongs to the histone H3 family. (136 aa)
DPF2Zinc finger protein ubi-d4 isoform X1. (414 aa)
GLYR1Putative oxidoreductase GLYR1. (553 aa)
RAD21L1Double-strand-break repair protein rad21-like protein 1. (555 aa)
CTC1CST complex subunit CTC1 isoform X1. (1210 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (437 aa)
MRGBPMRG/MORF4L-binding protein isoform X1. (255 aa)
BCL7AB-cell CLL/lymphoma 7 protein family member A isoform X1. (231 aa)
NCAPH2Condensin-2 complex subunit H2 isoform X1. (679 aa)
SMC1BStructural maintenance of chromosomes protein. (1240 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (735 aa)
LOC111186403Histone H1.0. (194 aa)
BCL11AB-cell lymphoma/leukemia 11A isoform X1. (888 aa)
SMC2Structural maintenance of chromosomes protein. (1191 aa)
EP400E1A-binding protein p400 isoform X1. (3133 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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