STRINGSTRING
ITGA4 ITGA4 ADD2 ADD2 SELL SELL F11R F11R CD99L2 CD99L2 CX3CR1 CX3CR1 SELE SELE SELP SELP CX3CL1 CX3CL1 SELPLG SELPLG CRKL CRKL EXT1 EXT1 JAML JAML CD99 CD99 XG XG PODXL2 PODXL2 TNF TNF GOLPH3 GOLPH3 ITGA1 ITGA1 TRIM55 TRIM55 CRK CRK FER FER PECAM1 PECAM1 ITGAL ITGAL LOC111182630 LOC111182630 ROCK1 ROCK1 GCNT1 GCNT1 JAM2 JAM2 ITGB7 ITGB7 MADCAM1 MADCAM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA4Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa)
ADD2Beta-adducin isoform X1. (836 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (372 aa)
F11RJunctional adhesion molecule A. (299 aa)
CD99L2CD99 antigen-like protein 2 isoform X1. (300 aa)
CX3CR1CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (475 aa)
SELEE-selectin. (531 aa)
SELPP-selectin isoform X1. (768 aa)
CX3CL1Fractalkine. (469 aa)
SELPLGP-selectin glycoprotein ligand 1. (450 aa)
CRKLCrk-like protein. (303 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
JAMLJunctional adhesion molecule-like. (383 aa)
CD99CD99 antigen isoform X1. (200 aa)
XGGlycoprotein Xg. (140 aa)
PODXL2Podocalyxin-like protein 2 isoform X1. (607 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
GOLPH3Golgi phosphoprotein 3. (298 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
TRIM55Tripartite motif-containing protein 55 isoform X1. (534 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
PECAM1Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
ITGALIntegrin alpha-L; Belongs to the integrin alpha chain family. (1166 aa)
LOC111182630Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
GCNT1beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase isoform X1. (485 aa)
JAM2Junctional adhesion molecule B isoform X1. (350 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (819 aa)
MADCAM1Mucosal addressin cell adhesion molecule 1. (406 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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