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SOX12 SOX12 AP3B1 AP3B1 ADA ADA BAD BAD ZMIZ1 ZMIZ1 VSIR VSIR SART1 SART1 AMBRA1 AMBRA1 CD74 CD74 KAT5 KAT5 RASGRP1 RASGRP1 MALT1 MALT1 CD83 CD83 TGFB1 TGFB1 IL4I1 IL4I1 IL7R IL7R LOC111187417 LOC111187417 NFKBIZ NFKBIZ SOX13 SOX13 PCK1 PCK1 LOC111187428 LOC111187428 PRKCZ PRKCZ PIK3R6 PIK3R6 CCL19 CCL19 SOCS1 SOCS1 XBP1 XBP1 FOXO3 FOXO3 TOX TOX VNN1 VNN1 MYB MYB RARA RARA MMP14 MMP14 STAT5A STAT5A LOC111166483 LOC111166483 IL7 IL7 SASH3 SASH3 ZBTB16 ZBTB16 PTPRC PTPRC TNFSF9 TNFSF9 ZBTB7B ZBTB7B EGR3 EGR3 FOXP3 FOXP3 SYK SYK IL2RG IL2RG LOC111169054 LOC111169054 LEF1 LEF1 IHH IHH BCL6 BCL6 PPP2R3C PPP2R3C RHOH RHOH INPP5D INPP5D ZBTB1 ZBTB1 NCKAP1L NCKAP1L ANXA1 ANXA1 ADAM8 ADAM8 SOCS5 SOCS5 WNT10B WNT10B RHOA RHOA LOC111175407 LOC111175407 IFNG IFNG SHH SHH CD27 CD27 PCID2 PCID2 ITPKB ITPKB GAS6 GAS6 HLX HLX LOC111176900 LOC111176900 DUSP10 DUSP10 GATA3 GATA3 AXL AXL SHB SHB IL15 IL15 IL1RL2 IL1RL2 GLI3 GLI3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOX12Transcription factor SOX. (312 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1087 aa)
ADAAdenosine deaminase isoform X1. (416 aa)
BADBcl2-associated agonist of cell death. (168 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1 isoform X1. (1071 aa)
VSIRV-type immunoglobulin domain-containing suppressor of T-cell activation. (311 aa)
SART1U4/U6.U5 tri-snRNP-associated protein 1. (803 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1295 aa)
CD74HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (870 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa)
CD83CD83 antigen isoform X1. (195 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
IL4I1L-amino-acid oxidase isoform X1. (653 aa)
IL7RInterleukin-7 receptor subunit alpha isoform X1. (459 aa)
LOC111187417Tyrosine-protein kinase. (612 aa)
NFKBIZNF-kappa-B inhibitor zeta. (726 aa)
SOX13Transcription factor SOX-13. (644 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1. (687 aa)
LOC111187428Interleukin-1. (118 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)
PIK3R6Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa)
CCL19C-C motif chemokine. (159 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa)
FOXO3Forkhead box protein O3. (672 aa)
TOXThymocyte selection-associated high mobility group box protein TOX isoform X1. (517 aa)
VNN1Pantetheinase. (514 aa)
MYBTranscriptional activator Myb isoform X3. (761 aa)
RARARetinoic acid receptor alpha isoform X5. (584 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
STAT5ASignal transducer and activator of transcription. (818 aa)
LOC111166483Signal transducer and activator of transcription. (787 aa)
IL7Interleukin-7 isoform X1. (226 aa)
SASH3SAM and SH3 domain-containing protein 3. (380 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16. (673 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
TNFSF9Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family. (252 aa)
ZBTB7BZinc finger and BTB domain-containing protein 7B. (541 aa)
EGR3Early growth response protein 3 isoform X1. (387 aa)
FOXP3Forkhead box protein P3. (431 aa)
SYKTyrosine-protein kinase. (626 aa)
IL2RGCytokine receptor common subunit gamma isoform X1. (381 aa)
LOC111169054NF-kappa-B-activating protein. (417 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (414 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (453 aa)
RHOHRho-related GTP-binding protein RhoH. (191 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
ZBTB1Zinc finger and BTB domain-containing protein 1. (713 aa)
NCKAP1LNck-associated protein 1-like isoform X1. (1156 aa)
ANXA1Annexin. (346 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
RHOATransforming protein RhoA. (193 aa)
LOC111175407Amine oxidase. (524 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
CD27CD27 antigen isoform X1. (251 aa)
PCID2PCI domain-containing protein 2 isoform X2. (399 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
HLXH2.0-like homeobox protein. (488 aa)
LOC111176900GTPase IMAP family member 5-like isoform X1. (332 aa)
DUSP10Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
SHBSH2 domain-containing adapter protein B. (507 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (180 aa)
IL1RL2Interleukin-1 receptor-like 2 isoform X1. (570 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1587 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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