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| | PLA2G3 | Group 3 secretory phospholipase A2 isoform X1. (516 aa) |
| | LIF | Leukemia inhibitory factor. (202 aa) |
| | LOC111163731 | C-C motif chemokine. (93 aa) |
| | C1QC | Complement C1q subcomponent subunit C. (245 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type 2 isoform X3. (474 aa) |
| | PITHD1 | PITH domain-containing protein 1 isoform X1. (211 aa) |
| | FOXO3 | Forkhead box protein O3. (672 aa) |
| | HSF1 | Heat shock factor protein 1 isoform X1. (564 aa) |
| | GPR137B | Integral membrane protein GPR137B. (385 aa) |
| | ETS1 | Protein C-ets-1 isoform X1. (486 aa) |
| | ZNF16 | Zinc finger protein 16 isoform X1. (666 aa) |
| | TRIB1 | Tribbles homolog 1. (372 aa) |
| | CTR9 | RNA polymerase-associated protein CTR9 homolog isoform X1. (1214 aa) |
| | LRRC17 | Leucine-rich repeat-containing protein 17 isoform X1. (440 aa) |
| | ABCB10 | ATP-binding cassette sub-family B member 10, mitochondrial. (731 aa) |
| | KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa) |
| | HOXB8 | Homeobox protein Hox-B8. (243 aa) |
| | RARA | Retinoic acid receptor alpha isoform X5. (584 aa) |
| | CSF3 | Granulocyte colony-stimulating factor. (195 aa) |
| | STAT5A | Signal transducer and activator of transcription. (818 aa) |
| | LOC111166483 | Signal transducer and activator of transcription. (787 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa) |
| | APCS | LOW QUALITY PROTEIN: serum amyloid P-component. (139 aa) |
| | LYN | Tyrosine-protein kinase. (518 aa) |
| | FBXW9 | F-box/WD repeat-containing protein 9 isoform X1. (461 aa) |
| | TNFRSF11B | Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa) |
| | UBASH3B | Ubiquitin-associated and SH3 domain-containing protein B isoform X1. (649 aa) |
| | HAX1 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (276 aa) |
| | RASSF2 | Ras association domain-containing protein 2 isoform X1. (420 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1221 aa) |
| | ZBTB16 | Zinc finger and BTB domain-containing protein 16. (673 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (799 aa) |
| | GATA1 | Erythroid transcription factor isoform X1. (426 aa) |
| | HCLS1 | Hematopoietic lineage cell-specific protein. (481 aa) |
| | FES | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | FSTL3 | Follistatin-related protein 3. (262 aa) |
| | TFE3 | Transcription factor E3 isoform X1. (575 aa) |
| | CIB1 | Calcium and integrin-binding protein 1. (191 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (414 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (518 aa) |
| | GPR55 | G-protein coupled receptor 55 isoform X1; Belongs to the G-protein coupled receptor 1 family. (407 aa) |
| | STAT1 | Signal transducer and activator of transcription. (749 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | TNFAIP6 | Tumor necrosis factor-inducible gene 6 protein isoform X1. (284 aa) |
| | OCSTAMP | LOW QUALITY PROTEIN: osteoclast stimulatory transmembrane protein. (566 aa) |
| | LDB1 | LIM domain-binding protein 1 isoform X3. (436 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (308 aa) |
| | INPP5D | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa) |
| | HIF1A | Hypoxia-inducible factor 1-alpha isoform X1. (823 aa) |
| | RARG | Retinoic acid receptor gamma isoform X1. (458 aa) |
| | SLC9B2 | Sodium/hydrogen exchanger 9B2 isoform X1. (536 aa) |
| | NCKAP1L | Nck-associated protein 1-like isoform X1. (1156 aa) |
| | MITF | Microphthalmia-associated transcription factor isoform X1. (526 aa) |
| | P4HTM | Transmembrane prolyl 4-hydroxylase. (494 aa) |
| | LOC111174848 | Uncharacterized protein LOC111174848 isoform X1. (334 aa) |
| | GABPA | GA-binding protein alpha chain. (454 aa) |
| | TCTA | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. (106 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa) |
| | RNF41 | E3 ubiquitin-protein ligase NRDP1 isoform X1. (317 aa) |
| | ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (546 aa) |
| | ZFP36L1 | mRNA decay activator protein ZFP36L1. (338 aa) |
| | GPR68 | Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (710 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa) |
| | FOXP1 | Forkhead box protein P1 isoform X1. (673 aa) |
| | POU4F1 | POU domain protein. (422 aa) |
| | TAL1 | T-cell acute lymphocytic leukemia protein 1 isoform X1. (328 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa) |
| | LEO1 | RNA polymerase-associated protein LEO1 isoform X1. (672 aa) |
| | LOC111174846 | Transmembrane protein 178A-like isoform X1. (177 aa) |
| | WDR61 | WD repeat-containing protein 61 isoform X2. (305 aa) |
| | CUL4A | cullin-4A; Belongs to the cullin family. (761 aa) |
| | CSF3R | Granulocyte colony-stimulating factor receptor isoform X1. (846 aa) |
| | IL17A | interleukin-17A. (155 aa) |
| | RCOR1 | REST corepressor 1 isoform X1. (497 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) |
| | ZFPM1 | Zinc finger protein ZFPM1 isoform X1. (1069 aa) |
| | LOC111177621 | RNA polymerase-associated protein LEO1-like. (292 aa) |
| | RBM15 | Putative RNA-binding protein 15. (962 aa) |
| | CNOT4 | CCR4-NOT transcription complex subunit 4 isoform X1. (714 aa) |
| | CDC73 | Parafibromin. (531 aa) |
| | DCSTAMP | LOW QUALITY PROTEIN: dendritic cell-specific transmembrane protein. (510 aa) |
| | GPR171 | Probable G-protein coupled receptor 171; Belongs to the G-protein coupled receptor 1 family. (319 aa) |
| | IL34 | Interleukin-34. (235 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (294 aa) |
| | ZFP36 | mRNA decay activator protein ZFP36. (325 aa) |
| | CDK6 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. (326 aa) |
| | PRMT1 | Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa) |
| | MTURN | Maturin. (131 aa) |
| | HOXA9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa) |
| | HOXA5 | Homeobox protein Hox-A5. (381 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | TMEM64 | Transmembrane protein 64. (382 aa) |
| | PAF1 | RNA polymerase II-associated factor 1 homolog isoform X1. (533 aa) |
| | SCIN | Adseverin isoform X1. (715 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | MEIS2 | Homeobox protein Meis2 isoform X1. (477 aa) |
| | NEDD9 | Enhancer of filamentation 1 isoform X1. (829 aa) |
| | CD101 | Immunoglobulin superfamily member 2 isoform X1. (1018 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 isoform X1. (687 aa) |
| | PIAS3 | E3 SUMO-protein ligase PIAS3 isoform X1. (628 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa) |
| | KLF10 | Krueppel-like factor 10 isoform X2. (494 aa) |
| | HOXA7 | Homeobox protein Hox-A7. (233 aa) |
| | PPARGC1B | Peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1. (1173 aa) |
| | FAXDC2 | Fatty acid hydroxylase domain-containing protein 2; Belongs to the sterol desaturase family. (333 aa) |
| | HSPA9 | Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. (679 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa) |
| | FBN1 | Fibrillin-1 isoform X1. (2871 aa) |
| | SMAP1 | Stromal membrane-associated protein 1 isoform X1. (472 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa) |
| | FAM213A | Redox-regulatory protein FAM213A isoform X3. (289 aa) |
| | LOX | Protein-lysine 6-oxidase isoform X1. (425 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | MEF2C | Myocyte-specific enhancer factor 2C isoform X6. (483 aa) |
| | NDFIP1 | NEDD4 family-interacting protein 1. (221 aa) |
| | MAFB | Transcription factor MafB. (323 aa) |
| | INHBA | Inhibin beta A chain. (425 aa) |
| | RAB7B | Ras-related protein Rab-7b isoform X1. (210 aa) |
| | GPR137 | Integral membrane protein GPR137 isoform X1. (395 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | CUNH1orf186 | Uncharacterized protein C1orf186 homolog isoform X1. (172 aa) |
| | ZBTB46 | Zinc finger and BTB domain-containing protein 46. (590 aa) |
| | BRD1 | Bromodomain-containing protein 1 isoform X2. (1187 aa) |
| | ANKRD54 | Ankyrin repeat domain-containing protein 54 isoform X1. (299 aa) |
| | PTK2B | Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa) |
| | MEIS1 | Homeobox protein Meis1 isoform X1. (465 aa) |
| | NF1 | Neurofibromin isoform X1. (2873 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (345 aa) |
| | EVI2B | Protein EVI2B. (451 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa) |
| | TOB2 | Protein Tob2. (343 aa) |
| | FAM210B | Protein FAM210B. (192 aa) |
| | FBXW7 | F-box/WD repeat-containing protein 7 isoform X1. (707 aa) |
| | RBFOX2 | RNA binding protein fox-1 homolog 2 isoform X1. (464 aa) |
| | TESC | Calcineurin B homologous protein 3. (214 aa) |
| | CTNNBIP1 | Beta-catenin-interacting protein 1. (81 aa) |
| | POU4F2 | POU domain protein. (407 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
