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EIF4ENIF1 EIF4ENIF1 NEPRO NEPRO OLIG2 OLIG2 ASCL1 ASCL1 FOXG1 FOXG1 TTC3 TTC3 ISL1 ISL1 IRX3 IRX3 NR2E1 NR2E1 ZHX2 ZHX2 HEY1 HEY1 MED1 MED1 JAG1 JAG1 DDX6 DDX6 GPR37L1 GPR37L1 LOC111168048 LOC111168048 LOC111169295 LOC111169295 CALR CALR LMX1A LMX1A WNT3A WNT3A LOC111166888 LOC111166888 DLL1 DLL1 LOC111169240 LOC111169240 PHOX2B PHOX2B CTDSP1 CTDSP1 DLX2 DLX2 GDF11 GDF11 CNTN4 CNTN4 HES1 HES1 LSM1 LSM1 LBX1 LBX1 DLX1 DLX1 FEZF2 FEZF2 SHH SHH APP APP EIF4E EIF4E NOTCH1 NOTCH1 ITGB1 ITGB1 ISL2 ISL2 HMG20A HMG20A HOXA2 HOXA2 MIB1 MIB1 PAX6 PAX6 LOC111182889 LOC111182889 ZNF536 ZNF536 CNTF CNTF CNTN2 CNTN2 SOX8 SOX8 NKX2-2 NKX2-2 GLI3 GLI3 HES5 HES5 TLX3 TLX3 MEIS1 MEIS1 DISP3 DISP3 HES3 HES3 BMP7 BMP7 POU4F2 POU4F2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF4ENIF1Eukaryotic translation initiation factor 4E transporter isoform X1. (1022 aa)
NEPRONucleolus and neural progenitor protein isoform X1. (563 aa)
OLIG2Oligodendrocyte transcription factor 2. (323 aa)
ASCL1Achaete-scute homolog 1. (225 aa)
FOXG1Forkhead box protein G1. (484 aa)
TTC3E3 ubiquitin-protein ligase TTC3 isoform X1. (2000 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
IRX3Iroquois-class homeodomain protein IRX-3. (502 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1 isoform X1. (385 aa)
ZHX2Zinc fingers and homeoboxes protein 2. (838 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1. (304 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1221 aa)
DDX6Probable ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family. (483 aa)
GPR37L1Prosaposin receptor GPR37L1. (464 aa)
LOC111168048Dixin-like isoform X1. (219 aa)
LOC111169295RE1-silencing transcription factor-like isoform X1. (981 aa)
CALRCalreticulin. (417 aa)
LMX1ALIM homeobox transcription factor 1-alpha. (382 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
LOC111166888Dixin. (468 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (799 aa)
LOC111169240RE1-silencing transcription factor-like isoform X2. (976 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (311 aa)
CTDSP1Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X1. (261 aa)
DLX2Homeobox protein DLX-2 isoform X1. (333 aa)
GDF11Growth/differentiation factor 11. (406 aa)
CNTN4Contactin-4 isoform X1. (1026 aa)
HES1Transcription factor HES-1. (280 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
LBX1Transcription factor LBX1. (281 aa)
DLX1Homeobox protein DLX-1 isoform X1. (255 aa)
FEZF2Fez family zinc finger protein 2. (458 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
APPAmyloid beta A4 protein isoform X1. (767 aa)
EIF4EEukaryotic translation initiation factor 4E isoform X1; Belongs to the eukaryotic initiation factor 4E family. (303 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
ISL2Insulin gene enhancer protein ISL-2. (334 aa)
HMG20AHigh mobility group protein 20A. (347 aa)
HOXA2Homeobox protein Hox-A2. (372 aa)
MIB1E3 ubiquitin-protein ligase MIB1. (1006 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
LOC111182889LOW QUALITY PROTEIN: transcription factor SOX-9-like. (510 aa)
ZNF536Zinc finger protein 536 isoform X1. (1319 aa)
CNTFCiliary neurotrophic factor. (200 aa)
CNTN2Contactin-2. (1043 aa)
SOX8Transcription factor SOX-8. (463 aa)
NKX2-2Homeobox protein Nkx-2.2 isoform X1. (273 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1587 aa)
HES5Transcription factor HES-5 isoform X1. (205 aa)
TLX3T-cell leukemia homeobox protein 3. (291 aa)
MEIS1Homeobox protein Meis1 isoform X1. (465 aa)
DISP3Protein dispatched homolog 3 isoform X1. (1395 aa)
HES3Transcription factor HES-3. (178 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
POU4F2POU domain protein. (407 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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