STRINGSTRING
TIGAR TIGAR LEPR LEPR FAM3C FAM3C TGFB1 TGFB1 CBFA2T3 CBFA2T3 SMPD3 SMPD3 ERFE ERFE NCOR1 NCOR1 FLCN FLCN SIRT6 SIRT6 STAT3 STAT3 CLTC CLTC SIK1 SIK1 LOC111163647 LOC111163647 INPP5K INPP5K PPARA PPARA PGP PGP EP300 EP300 GIT1 GIT1 C1QTNF12 C1QTNF12 PLEK PLEK C1QTNF3 C1QTNF3 CRY1 CRY1 INS INS GCK GCK ACTN3 ACTN3 DDIT4 DDIT4 AP2A1 AP2A1 NUPR1 NUPR1 FBP1 FBP1 AGPAT4 AGPAT4 MIDN MIDN ENPP1 ENPP1 LOC111169221 LOC111169221 FAM3A FAM3A SLC4A1 SLC4A1 HDAC4 HDAC4 PASK PASK MST1 MST1 GCKR GCKR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TIGARFructose-2,6-bisphosphatase TIGAR isoform X1. (325 aa)
LEPRLeptin receptor isoform X1. (917 aa)
FAM3CProtein FAM3C isoform X1. (234 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
CBFA2T3Protein CBFA2T3 isoform X1. (648 aa)
SMPD3Sphingomyelin phosphodiesterase 3 isoform X1. (706 aa)
ERFEErythroferrone isoform X1. (367 aa)
NCOR1Nuclear receptor corepressor 1 isoform X1. (2454 aa)
FLCNFolliculin isoform X1. (591 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6 isoform X3. (375 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
SIK1Serine/threonine-protein kinase SIK1. (784 aa)
LOC111163647Cytochrome c oxidase assembly protein COX11, mitochondrial. (271 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform X1. (476 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
PGPGlycerol-3-phosphate phosphatase; Belongs to the HAD-like hydrolase superfamily. (321 aa)
EP300Histone acetyltransferase p300. (2420 aa)
GIT1ARF GTPase-activating protein GIT1 isoform X1. (770 aa)
C1QTNF12Adipolin. (299 aa)
PLEKPleckstrin. (350 aa)
C1QTNF3Complement C1q tumor necrosis factor-related protein 3 isoform X1. (319 aa)
CRY1Cryptochrome-1 isoform X1. (587 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
GCKPhosphotransferase. (537 aa)
ACTN3Alpha-actinin-3 isoform X1. (902 aa)
DDIT4DNA damage-inducible transcript 4 protein. (229 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (1023 aa)
NUPR1Nuclear protein 1. (82 aa)
FBP1Fructose-1,6-bisphosphatase 1 isoform X1; Belongs to the FBPase class 1 family. (338 aa)
AGPAT41-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1. (835 aa)
MIDNMidnolin isoform X1. (496 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1. (925 aa)
LOC111169221LOW QUALITY PROTEIN: protein FAM3C-like. (227 aa)
FAM3AProtein FAM3A isoform X1. (304 aa)
SLC4A1Anion exchange protein. (963 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1083 aa)
PASKPAS domain-containing serine/threonine-protein kinase. (1325 aa)
MST1Hepatocyte growth factor-like protein isoform X1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
GCKRLOW QUALITY PROTEIN: glucokinase regulatory protein. (618 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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