65 items (Delphinapterus leucas) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

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Your Input:
	HYAL3	Hyaluronidase. (415 aa)
	SYT10	Synaptotagmin-10. (523 aa)
	PLA2G3	Group 3 secretory phospholipase A2 isoform X1. (516 aa)
	FGR	Tyrosine-protein kinase. (526 aa)
	F2RL1	Proteinase-activated receptor 2. (315 aa)
	CNR1	Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
	VSNL1	Visinin-like protein 1. (191 aa)
	RAB3D	Ras-related protein Rab-3D. (219 aa)
	SNF8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
	RAB3A	Ras-related protein Rab-3A. (220 aa)
	CD177	CD177 antigen isoform X1. (443 aa)
	IL13	Interleukin-13. (131 aa)
	RAB27B	Ras-related protein Rab-27B. (217 aa)
	CADPS2	Calcium-dependent secretion activator 2 isoform X1. (1305 aa)
	CACNB2	Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (604 aa)
	VPS4B	Vacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (444 aa)
	VPS4A	Vacuolar protein sorting-associated protein 4A isoform X1; Belongs to the AAA ATPase family. (437 aa)
	VAMP8	Vesicle-associated membrane protein 8. (100 aa)
	RAB5A	Ras-related protein Rab-5A isoform X1. (215 aa)
	SYT1	Synaptotagmin-1 isoform X1. (422 aa)
	ADORA2B	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (333 aa)
	CACNA1A	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2501 aa)
	STXBP5	Syntaxin-binding protein 5 isoform X5. (1181 aa)
	EXPH5	Exophilin-5 isoform X1. (2002 aa)
	SYT2	Synaptotagmin-2 isoform X1. (428 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	RAB7A	Ras-related protein Rab-7a. (207 aa)
	STX1A	syntaxin-1A isoform X1; Belongs to the syntaxin family. (288 aa)
	TSG101	Tumor susceptibility gene 101 protein isoform X1. (429 aa)
	RAB2B	Ras-related protein Rab-2B isoform X1. (216 aa)
	UNC13D	Protein unc-13 homolog D isoform X1. (1121 aa)
	CACNA1H	Voltage-dependent T-type calcium channel subunit alpha-1H isoform X1. (2335 aa)
	CACNA1I	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2193 aa)
	KIAA0100	Protein KIAA0100 homolog isoform X2. (2233 aa)
	GAB2	GRB2-associated-binding protein 2 isoform X1. (678 aa)
	FGB	Fibrinogen beta chain isoform X1. (495 aa)
	FGG	Fibrinogen gamma chain isoform X1. (445 aa)
	SPHK2	Sphingosine kinase 2 isoform X1. (655 aa)
	ITGAM	Integrin alpha-M; Belongs to the integrin alpha chain family. (872 aa)
	ZP3	Zona pellucida sperm-binding protein 3. (421 aa)
	HGS	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
	ATP13A2	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (966 aa)
	CACNA1B	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (1749 aa)
	LAMP1	Lysosome-associated membrane glycoprotein 1. (411 aa)
	STXBP1	Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
	CHMP2A	Charged multivesicular body protein 2a isoform X1. (305 aa)
	RAB27A	Ras-related protein Rab-27A isoform X1. (221 aa)
	SYTL4	Synaptotagmin-like protein 4. (672 aa)
	CDK5	Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	STAM	Signal transducing adapter molecule 1. (526 aa)
	RAB9A	Ras-related protein Rab-9A. (201 aa)
	VAMP7	Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
	AP1G1	AP-1 complex subunit gamma. (825 aa)
	SCAMP5	Secretory carrier-associated membrane protein. (235 aa)
	CDK5R2	Cyclin-dependent kinase 5 activator. (369 aa)
	CACNB4	Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (519 aa)
	NLGN1	Neuroligin-1 isoform X1. (843 aa)
	LOC111171171	Integrin alpha-M-like. (296 aa)
	LOC111171395	Cation-transporting ATPase 13A2-like. (209 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
	SNX4	Sorting nexin-4. (450 aa)
	CADPS	Calcium-dependent secretion activator 1 isoform X1. (1428 aa)
	SLC4A8	Anion exchange protein. (1109 aa)
	RAB15	Ras-related protein Rab-15 isoform X1. (212 aa)
	SDC1	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1G1	CHMP2A	A0A2Y9NVF7	A0A2Y9MHW4	AP-1 complex subunit gamma.	Charged multivesicular body protein 2a isoform X1.	0.593
AP1G1	HGS	A0A2Y9NVF7	A0A2Y9PID2	AP-1 complex subunit gamma.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.639
AP1G1	HYAL3	A0A2Y9NVF7	A0A2Y9NBE2	AP-1 complex subunit gamma.	Hyaluronidase.	0.468
AP1G1	RAB9A	A0A2Y9NVF7	A0A2Y9MI55	AP-1 complex subunit gamma.	Ras-related protein Rab-9A.	0.498
AP1G1	SNF8	A0A2Y9NVF7	A0A2Y9LVB2	AP-1 complex subunit gamma.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.600
AP1G1	SNX4	A0A2Y9NVF7	A0A2Y9N2L8	AP-1 complex subunit gamma.	Sorting nexin-4.	0.529
AP1G1	VAMP7	A0A2Y9NVF7	A0A2Y9MII7	AP-1 complex subunit gamma.	Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family.	0.630
AP1G1	VAMP8	A0A2Y9NVF7	A0A2Y9LXJ5	AP-1 complex subunit gamma.	Vesicle-associated membrane protein 8.	0.646
ATP13A2	LOC111171395	A0A2Y9QFH4	A0A2Y9N018	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Cation-transporting ATPase 13A2-like.	0.890
CACNA1A	CACNA1B	A0A2Y9M5G1	A0A2Y9NFJ0	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	0.931
CACNA1A	CACNA1H	A0A2Y9M5G1	A0A2Y9PX99	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent T-type calcium channel subunit alpha-1H isoform X1.	0.595
CACNA1A	CACNA1I	A0A2Y9M5G1	A0A2Y9PZK8	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.573
CACNA1A	CACNB2	A0A2Y9M5G1	A0A2Y9P2I5	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent L-type calcium channel subunit beta-2 isoform X1.	0.886
CACNA1A	CACNB4	A0A2Y9M5G1	A0A2Y9MU08	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent L-type calcium channel subunit beta-4 isoform X1.	0.914
CACNA1B	CACNA1A	A0A2Y9NFJ0	A0A2Y9M5G1	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	0.931
CACNA1B	CACNA1H	A0A2Y9NFJ0	A0A2Y9PX99	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	Voltage-dependent T-type calcium channel subunit alpha-1H isoform X1.	0.588
CACNA1B	CACNA1I	A0A2Y9NFJ0	A0A2Y9PZK8	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.573
CACNA1B	CACNB2	A0A2Y9NFJ0	A0A2Y9P2I5	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	Voltage-dependent L-type calcium channel subunit beta-2 isoform X1.	0.884
CACNA1B	CACNB4	A0A2Y9NFJ0	A0A2Y9MU08	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	Voltage-dependent L-type calcium channel subunit beta-4 isoform X1.	0.918
CACNA1B	STX1A	A0A2Y9NFJ0	A0A2Y9PKI0	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	syntaxin-1A isoform X1; Belongs to the syntaxin family.	0.914