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| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa) |
| | PLCD1 | Phosphoinositide phospholipase C. (817 aa) |
| | MTMR3 | Myotubularin-related protein 3 isoform X1. (1202 aa) |
| | PIGW | Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (502 aa) |
| | SOCS2 | Suppressor of cytokine signaling 2. (198 aa) |
| | MTMR4 | Myotubularin-related protein 4 isoform X1. (1211 aa) |
| | SMG1 | Serine/threonine-protein kinase SMG1 isoform X1; Belongs to the PI3/PI4-kinase family. (3658 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (215 aa) |
| | DGKE | Diacylglycerol kinase. (578 aa) |
| | IMPA1 | Inositol-1-monophosphatase. (277 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) |
| | INPP5J | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1. (980 aa) |
| | IMPA2 | Inositol-1-monophosphatase. (288 aa) |
| | PIP4K2B | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta. (416 aa) |
| | PGAP3 | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (320 aa) |
| | PIK3C2A | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1; Belongs to the PI3/PI4-kinase family. (1711 aa) |
| | DPM3 | Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (92 aa) |
| | PIGC | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C. (297 aa) |
| | SOCS7 | Suppressor of cytokine signaling 7 isoform X1. (641 aa) |
| | PIGM | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (423 aa) |
| | PIGL | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase. (253 aa) |
| | MTM1 | Myotubularin isoform X1. (603 aa) |
| | SYNJ2 | Synaptojanin-2 isoform X1. (1478 aa) |
| | OCRL | Inositol polyphosphate 5-phosphatase OCRL-1 isoform X1. (893 aa) |
| | PIP5K1C | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1. (718 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa) |
| | PIK3R4 | Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa) |
| | GPLD1 | Phosphatidylinositol-glycan-specific phospholipase D isoform X1. (849 aa) |
| | SH3YL1 | SH3 domain-containing YSC84-like protein 1 isoform X1. (342 aa) |
| | PIGA | Phosphatidylinositol N-acetylglucosaminyltransferase subunit A isoform X1. (485 aa) |
| | CDS1 | Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa) |
| | BECN1 | Beclin-1 isoform X5. (471 aa) |
| | SLC27A1 | Long-chain fatty acid transport protein 1 isoform X1. (675 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | PIP5K1A | Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa) |
| | MTMR11 | LOW QUALITY PROTEIN: myotubularin-related protein 11. (710 aa) |
| | PI4KB | Phosphatidylinositol 4-kinase beta isoform X1; Belongs to the PI3/PI4-kinase family. (832 aa) |
| | LOC111170544 | post-GPI attachment to proteins factor 2-like isoform X4. (251 aa) |
| | MTMR1 | Myotubularin-related protein 1 isoform X1. (685 aa) |
| | MTMR2 | Myotubularin-related protein 2 isoform X1. (643 aa) |
| | INPP1 | Inositol polyphosphate 1-phosphatase. (402 aa) |
| | PI4K2B | Phosphatidylinositol 4-kinase type 2-beta. (488 aa) |
| | INPP5F | Phosphatidylinositide phosphatase SAC2 isoform X1. (1173 aa) |
| | INPP5A | Type I inositol 1,4,5-trisphosphate 5-phosphatase isoform X1. (534 aa) |
| | INPPL1 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1. (1264 aa) |
| | PI4K2A | Phosphatidylinositol 4-kinase type 2-alpha. (479 aa) |
| | PIGZ | Mannosyltransferase. (563 aa) |
| | LOC111171574 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y-like. (71 aa) |
| | PGAP2 | post-GPI attachment to proteins factor 2 isoform X7. (315 aa) |
| | PLCD4 | Phosphoinositide phospholipase C. (821 aa) |
| | SOCS4 | Suppressor of cytokine signaling 4. (440 aa) |
| | INPP5D | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CWH43 | LOW QUALITY PROTEIN: PGAP2-interacting protein. (354 aa) |
| | PGAP1 | GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa) |
| | FAM126B | Protein FAM126B isoform X1. (586 aa) |
| | PIKFYVE | 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1. (2110 aa) |
| | IP6K1 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa) |
| | PIP5K1B | Phosphatidylinositol 4-phosphate 5-kinase type-1 beta. (540 aa) |
| | PIGH | Phosphatidylinositol N-acetylglucosaminyltransferase subunit H isoform X1. (231 aa) |
| | IP6K2 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | LCLAT1 | Lysocardiolipin acyltransferase 1 isoform X2. (475 aa) |
| | MTMR7 | Myotubularin-related protein 7 isoform X1. (660 aa) |
| | MTMR6 | Myotubularin-related protein 6. (622 aa) |
| | LOC111175271 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like isoform X1. (596 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | SACM1L | Phosphatidylinositide phosphatase SAC1 isoform X1. (587 aa) |
| | INPP5B | Type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1. (994 aa) |
| | ATG14 | Beclin 1-associated autophagy-related key regulator. (492 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa) |
| | TTC7B | Tetratricopeptide repeat protein 7B isoform X1. (843 aa) |
| | CISH | Cytokine-inducible SH2-containing protein isoform X1. (254 aa) |
| | PIGO | GPI ethanolamine phosphate transferase 3 isoform X1. (1131 aa) |
| | INPP4B | Type II inositol 3,4-bisphosphate 4-phosphatase isoform X2. (754 aa) |
| | LOC111187436 | Type I inositol 3,4-bisphosphate 4-phosphatase isoform X4. (974 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa) |
| | LOC111187172 | Phosphoinositide phospholipase C. (1150 aa) |
| | CCDC180 | LOW QUALITY PROTEIN: coiled-coil domain-containing protein 180. (1737 aa) |
| | PLEK | Pleckstrin. (350 aa) |
| | TMEM246 | Transmembrane protein 246. (403 aa) |
| | MTMR12 | Myotubularin-related protein 12 isoform X2. (776 aa) |
| | PIK3R6 | Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | DPM1 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (260 aa) |
| | PIGS | GPI transamidase component PIG-S isoform X1. (579 aa) |
| | MTMR9 | Myotubularin-related protein 9. (549 aa) |
| | PLA2G3 | Group 3 secretory phospholipase A2 isoform X1. (516 aa) |
| | UVRAG | UV radiation resistance-associated gene protein. (699 aa) |
| | LPGAT1 | acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1. (420 aa) |
| | INPP5K | Inositol polyphosphate 5-phosphatase K isoform X1. (476 aa) |
| | SLA2 | Src-like-adapter 2 isoform X1. (276 aa) |
| | PIGT | GPI transamidase component PIG-T. (578 aa) |
| | PIGQ | Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q isoform X1. (630 aa) |
| | PIK3C2B | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family. (1634 aa) |
| | CSF1R | Macrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa) |
| | PI4KA | Phosphatidylinositol 4-kinase alpha isoform X1; Belongs to the PI3/PI4-kinase family. (2149 aa) |
| | PIGU | Phosphatidylinositol glycan anchor biosynthesis class U protein. (435 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa) |
| | ITPKA | Kinase; Belongs to the inositol phosphokinase (IPK) family. (460 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (237 aa) |
| | MBOAT7 | Lysophospholipid acyltransferase 7 isoform X1; Belongs to the membrane-bound acyltransferase family. (504 aa) |
| | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (213 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (373 aa) |
| | FAM126A | Hyccin isoform X1. (521 aa) |
| | SOCS6 | Suppressor of cytokine signaling 6. (535 aa) |
| | LOC111180171 | LOW QUALITY PROTEIN: phosphatidylinositide phosphatase SAC2-like. (615 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa) |
| | VAC14 | Protein VAC14 homolog. (783 aa) |
| | ITPKC | Kinase; Belongs to the inositol phosphokinase (IPK) family. (685 aa) |
| | PIGN | GPI ethanolamine phosphate transferase 1 isoform X1. (931 aa) |
| | LOC111177839 | Protein preY, mitochondrial-like. (110 aa) |
| | FAM102B | Protein FAM102B isoform X1. (377 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | BPNT1 | 3'(2'),5'-bisphosphate nucleotidase 1. (308 aa) |
| | PYURF | Protein preY, mitochondrial. (114 aa) |
| | PIGX | Phosphatidylinositol-glycan biosynthesis class X protein. (298 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | PIGB | Mannosyltransferase. (541 aa) |
| | PIP4K2A | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1. (461 aa) |
| | PIGY | Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y. (71 aa) |
| | INPP5E | 72 kDa inositol polyphosphate 5-phosphatase. (627 aa) |
| | IP6K3 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (389 aa) |
| | PIGK | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (395 aa) |
| | LOC111177840 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y-like. (71 aa) |
| | PIK3C2G | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family. (1483 aa) |
| | DPM2 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (84 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa) |
| | FAM102A | Protein FAM102A. (384 aa) |
| | PIP5KL1 | Phosphatidylinositol 4-phosphate 5-kinase-like protein 1. (413 aa) |
| | PIP4K2C | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (421 aa) |
| | TTC7A | Tetratricopeptide repeat protein 7A isoform X1. (858 aa) |
| | LOC111175512 | LOW QUALITY PROTEIN: myotubularin-related protein 9-like. (540 aa) |
| | PIGG | GPI ethanolamine phosphate transferase 2 isoform X1. (983 aa) |
| | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | FIG4 | Polyphosphoinositide phosphatase isoform X1. (907 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | IMPAD1 | Inositol monophosphatase 3. (359 aa) |
| | GPAA1 | Glycosylphosphatidylinositol anchor attachment 1 protein isoform X1. (622 aa) |
| | PIGV | GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (493 aa) |
| | LOC111163199 | LOW QUALITY PROTEIN: phosphatidylinositide phosphatase SAC1-like. (535 aa) |
| | TMEM150A | Transmembrane protein 150A. (305 aa) |
| | SYNJ1 | Synaptojanin-1 isoform X2. (1592 aa) |
| | PIGP | Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. (146 aa) |
| | MTMR10 | Myotubularin-related protein 10 isoform X1. (772 aa) |
| | MPPE1 | Metallophosphoesterase 1 isoform X1. (427 aa) |
