Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACOX1 | PEX14 | A0A2Y9PHG7 | A0A2Y9Q5V0 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Peroxisomal membrane protein PEX14 isoform X1. | 0.827 |
| ACOX1 | PEX5 | A0A2Y9PHG7 | A0A2Y9NE32 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Peroxisomal biogenesis factor 5 isoform X1. | 0.809 |
| ALG2 | BIVM | A0A2Y9QLC9 | A0A2Y9NSW8 | Alpha-1,3/1,6-mannosyltransferase ALG2. | Basic immunoglobulin-like variable motif-containing protein isoform X1. | 0.435 |
| ALG2 | ERCC4 | A0A2Y9QLC9 | A0A2Y9LE17 | Alpha-1,3/1,6-mannosyltransferase ALG2. | DNA repair endonuclease XPF. | 0.446 |
| ALG2 | ERCC5 | A0A2Y9QLC9 | A0A2Y9NSV9 | Alpha-1,3/1,6-mannosyltransferase ALG2. | DNA repair protein complementing XP-G cells isoform X1. | 0.435 |
| ARF6 | EXOC2 | A0A2Y9MWV5 | A0A2Y9PG64 | ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. | 0.463 |
| ARF6 | EXOC4 | A0A2Y9MWV5 | A0A2Y9NTZ4 | ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | Exocyst complex component 4. | 0.431 |
| ARF6 | EXOC5 | A0A2Y9MWV5 | A0A2Y9MUU4 | ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | Exocyst complex component 5. | 0.551 |
| ARF6 | STX5 | A0A2Y9MWV5 | A0A2Y9PQD5 | ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | Syntaxin-5; Belongs to the syntaxin family. | 0.413 |
| ATM | BIVM | A0A2Y9M6F8 | A0A2Y9NSW8 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Basic immunoglobulin-like variable motif-containing protein isoform X1. | 0.604 |
| ATM | DAXX | A0A2Y9M6F8 | A0A2Y9P575 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Death domain-associated protein 6 isoform X1. | 0.405 |
| ATM | ERCC2 | A0A2Y9M6F8 | A0A2Y9P1Y9 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | TFIIH basal transcription factor complex helicase XPD subunit isoform X1. | 0.624 |
| ATM | ERCC3 | A0A2Y9M6F8 | A0A2Y9PKI5 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | TFIIH basal transcription factor complex helicase XPB subunit isoform X1. | 0.461 |
| ATM | ERCC4 | A0A2Y9M6F8 | A0A2Y9LE17 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | DNA repair endonuclease XPF. | 0.560 |
| ATM | ERCC5 | A0A2Y9M6F8 | A0A2Y9NSV9 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | DNA repair protein complementing XP-G cells isoform X1. | 0.604 |
| ATM | GADD45A | A0A2Y9M6F8 | A0A2Y9NS28 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Growth arrest and DNA damage-inducible protein GADD45 alpha. | 0.435 |
| ATM | HDAC1 | A0A2Y9M6F8 | A0A2Y9N7S9 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | 0.566 |
| ATM | NBN | A0A2Y9M6F8 | A0A2Y9P5N1 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. | 0.997 |
| ATM | PARP1 | A0A2Y9M6F8 | A0A2Y9NQ81 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. | 0.632 |
| ATM | PEX5 | A0A2Y9M6F8 | A0A2Y9NE32 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Peroxisomal biogenesis factor 5 isoform X1. | 0.932 |
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