(12 nodes) Embryonic digestive tract morphogenesis network (Delphinapterus leucas)

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second shell of interactors

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Your Input:
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
	TCF21	Transcription factor 21. (179 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	ID2	DNA-binding protein inhibitor ID-2. (134 aa)
	NIPBL	Nipped-B protein. (2803 aa)
	GLI3	Transcriptional activator GLI3 isoform X1. (1587 aa)
	FOXF1	Forkhead box protein F1. (375 aa)
	HLX	H2.0-like homeobox protein. (488 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
	SIX2	Homeobox protein SIX2. (296 aa)
	SHOX2	Short stature homeobox protein 2 isoform X1. (329 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGF10	IHH	A0A2Y9LQ50	A0A2Y9MSV0	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.662
FGF10	PDGFRA	A0A2Y9LQ50	A0A2Y9MC65	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	0.873
FGF10	SHH	A0A2Y9LQ50	A0A2Y9NDZ2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.771
FOXF1	GLI3	A0A2Y9NXD1	A0A2Y9Q038	Forkhead box protein F1.	Transcriptional activator GLI3 isoform X1.	0.482
FOXF1	SHH	A0A2Y9NXD1	A0A2Y9NDZ2	Forkhead box protein F1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.435
FOXF1	TCF21	A0A2Y9NXD1	A0A2Y9LTL8	Forkhead box protein F1.	Transcription factor 21.	0.416
GLI3	FOXF1	A0A2Y9Q038	A0A2Y9NXD1	Transcriptional activator GLI3 isoform X1.	Forkhead box protein F1.	0.482
GLI3	IHH	A0A2Y9Q038	A0A2Y9MSV0	Transcriptional activator GLI3 isoform X1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.721
GLI3	PDGFRA	A0A2Y9Q038	A0A2Y9MC65	Transcriptional activator GLI3 isoform X1.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	0.616
GLI3	SHH	A0A2Y9Q038	A0A2Y9NDZ2	Transcriptional activator GLI3 isoform X1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.751
IHH	FGF10	A0A2Y9MSV0	A0A2Y9LQ50	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.662
IHH	GLI3	A0A2Y9MSV0	A0A2Y9Q038	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Transcriptional activator GLI3 isoform X1.	0.721
IHH	SHH	A0A2Y9MSV0	A0A2Y9NDZ2	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.946
PDGFRA	FGF10	A0A2Y9MC65	A0A2Y9LQ50	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.873
PDGFRA	GLI3	A0A2Y9MC65	A0A2Y9Q038	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	Transcriptional activator GLI3 isoform X1.	0.616
PDGFRA	SHH	A0A2Y9MC65	A0A2Y9NDZ2	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.500
PDGFRA	TCF21	A0A2Y9MC65	A0A2Y9LTL8	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	Transcription factor 21.	0.440
SHH	FGF10	A0A2Y9NDZ2	A0A2Y9LQ50	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.771
SHH	FOXF1	A0A2Y9NDZ2	A0A2Y9NXD1	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Forkhead box protein F1.	0.435
SHH	GLI3	A0A2Y9NDZ2	A0A2Y9Q038	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Transcriptional activator GLI3 isoform X1.	0.751