STRINGSTRING
SLC6A4 SLC6A4 WWC1 WWC1 NTN1 NTN1 SEMA4C SEMA4C ULK1 ULK1 TP73 TP73 MAPK11 MAPK11 RTN4 RTN4 DRAXIN DRAXIN PLAC8 PLAC8 DIP2B DIP2B SEMA3B SEMA3B IFRD2 IFRD2 SPART SPART ADRB3 ADRB3 WNT5A WNT5A SEMA3F SEMA3F OSTN OSTN SEMA5B SEMA5B WWC2 WWC2 SAV1 SAV1 ADRB1 ADRB1 BMP4 BMP4 PLXNA3 PLXNA3 TLL2 TLL2 SEMA4G SEMA4G MSTN MSTN LOC111168870 LOC111168870 SEMA3E SEMA3E SEMA3D SEMA3D LOC111168869 LOC111168869 SEMA6C SEMA6C SEMA4B SEMA4B WNT3A WNT3A LOC111168867 LOC111168867 SEMA4F SEMA4F KIAA0319 KIAA0319 SEMA4A SEMA4A TNR TNR SEMA4D SEMA4D RAI1 RAI1 LOC111167234 LOC111167234 PTPRS PTPRS PTCH1 PTCH1 GDF15 GDF15 NKD1 NKD1 SEMA6B SEMA6B EPHA7 EPHA7 SEMA3C SEMA3C BBS2 BBS2 NOG NOG SOCS2 SOCS2 RTN4R RTN4R TBX5 TBX5 PI16 PI16 CDKN1B CDKN1B DUSP10 DUSP10 SEMA5A SEMA5A RYK RYK JARID2 JARID2 GSK3A GSK3A CDKN1A CDKN1A CDK5 CDK5 SEMA7A SEMA7A LGMN LGMN FXN FXN SEMA3G SEMA3G FSTL4 FSTL4 SEMA6D SEMA6D STK3 STK3 WNT3 WNT3 SEMA6A SEMA6A MYOZ1 MYOZ1 ADRB2 ADRB2 STK4 STK4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
WWC1Protein KIBRA. (1109 aa)
NTN1Netrin-1. (604 aa)
SEMA4Csemaphorin-4C isoform X1; Belongs to the semaphorin family. (945 aa)
ULK1Serine/threonine-protein kinase ULK1 isoform X1. (1055 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (637 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
RTN4Reticulon. (1192 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (350 aa)
PLAC8Placenta-specific gene 8 protein. (113 aa)
DIP2BDisco-interacting protein 2 homolog B isoform X1. (1576 aa)
SEMA3Bsemaphorin-3B isoform X1; Belongs to the semaphorin family. (748 aa)
IFRD2Interferon-related developmental regulator 2 isoform X1. (442 aa)
SPARTSpartin. (668 aa)
ADRB3LOW QUALITY PROTEIN: beta-3 adrenergic receptor. (391 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
SEMA3Fsemaphorin-3F isoform X1; Belongs to the semaphorin family. (785 aa)
OSTNOsteocrin. (132 aa)
SEMA5Bsemaphorin-5B isoform X1. (1093 aa)
WWC2Protein WWC2. (1193 aa)
SAV1Protein salvador homolog 1. (385 aa)
ADRB1Beta-1 adrenergic receptor. (470 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (408 aa)
PLXNA3plexin-A3. (1872 aa)
TLL2Metalloendopeptidase. (1020 aa)
SEMA4Gsemaphorin-4G isoform X1; Belongs to the semaphorin family. (843 aa)
MSTNGrowth/differentiation factor 8. (375 aa)
LOC111168870semaphorin-3A-like; Belongs to the semaphorin family. (249 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (775 aa)
SEMA3Dsemaphorin-3D isoform X1; Belongs to the semaphorin family. (777 aa)
LOC111168869semaphorin-3A-like; Belongs to the semaphorin family. (273 aa)
SEMA6Csemaphorin-6C isoform X5; Belongs to the semaphorin family. (966 aa)
SEMA4Bsemaphorin-4B; Belongs to the semaphorin family. (822 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
LOC111168867semaphorin-3A isoform X1. (306 aa)
SEMA4Fsemaphorin-4F isoform X1; Belongs to the semaphorin family. (789 aa)
KIAA0319Dyslexia-associated protein KIAA0319 homolog isoform X1. (1076 aa)
SEMA4Asemaphorin-4A; Belongs to the semaphorin family. (762 aa)
TNRtenascin-R isoform X1. (1358 aa)
SEMA4Dsemaphorin-4D isoform X1; Belongs to the semaphorin family. (863 aa)
RAI1Retinoic acid-induced protein 1 isoform X1. (1948 aa)
LOC111167234Protein WWC3-like isoform X1. (1214 aa)
PTPRSReceptor-type tyrosine-protein phosphatase S isoform X1. (1939 aa)
PTCH1Protein patched homolog 1 isoform X1. (1447 aa)
GDF15Growth/differentiation factor 15. (308 aa)
NKD1Protein naked cuticle homolog 1. (471 aa)
SEMA6Bsemaphorin-6B; Belongs to the semaphorin family. (880 aa)
EPHA7Ephrin type-A receptor 7 isoform X1. (998 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
RTN4RReticulon-4 receptor. (481 aa)
TBX5T-box transcription factor TBX5 isoform X1. (519 aa)
PI16Peptidase inhibitor 16 isoform X1; Belongs to the CRISP family. (463 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
DUSP10Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
SEMA5Asemaphorin-5A isoform X1. (1079 aa)
RYKTyrosine-protein kinase RYK isoform X1. (609 aa)
JARID2Protein Jumonji isoform X1. (1235 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (665 aa)
LGMNLegumain. (433 aa)
FXNFrataxin, mitochondrial. (213 aa)
SEMA3Gsemaphorin-3G isoform X1; Belongs to the semaphorin family. (773 aa)
FSTL4Follistatin-related protein 4 isoform X1. (704 aa)
SEMA6Dsemaphorin-6D isoform X1; Belongs to the semaphorin family. (1073 aa)
STK3Serine/threonine-protein kinase 3. (491 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa)
SEMA6Asemaphorin-6A isoform X1; Belongs to the semaphorin family. (1044 aa)
MYOZ1Myozenin-1. (298 aa)
ADRB2Beta-2 adrenergic receptor isoform X1. (400 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (487 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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