STRINGSTRING
CD80 CD80 TMEM131L TMEM131L PELI1 PELI1 CEBPB CEBPB LGALS9 LGALS9 ITCH ITCH CBLB CBLB DLG2 DLG2 LRRC32 LRRC32 RASSF5 RASSF5 IL10 IL10 BLK BLK TSPAN32 TSPAN32 DLG5 DLG5 VSIR VSIR NDFIP1 NDFIP1 PRKAR1A PRKAR1A LOC111182867 LOC111182867 TYROBP TYROBP FOXJ1 FOXJ1 GPNMB GPNMB TNFRSF21 TNFRSF21 IL4I1 IL4I1 TGFB1 TGFB1 IL20RB IL20RB LRRC1 LRRC1 BTK BTK LOC111178657 LOC111178657 PTPN6 PTPN6 SHH SHH PDCD1LG2 PDCD1LG2 LOC111175407 LOC111175407 IDO1 IDO1 CD274 CD274 ARG2 ARG2 INPP5D INPP5D CTLA4 CTLA4 BMP4 BMP4 MARCH7 MARCH7 IHH IHH DLG1 DLG1 MAD1L1 MAD1L1 RC3H1 RC3H1 CD86 CD86 SOX11 SOX11 TNFRSF13B TNFRSF13B FOXP3 FOXP3 VSIG4 VSIG4 ZBTB7B ZBTB7B ATM ATM CRTAM CRTAM ERBB2 ERBB2 PAWR PAWR LYN LYN PKN1 PKN1 LOC111166170 LOC111166170 PLA2G2D PLA2G2D GLMN GLMN TWSG1 TWSG1 PLA2G2F PLA2G2F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD80T-lymphocyte activation antigen CD80 isoform X1. (295 aa)
TMEM131LTransmembrane protein 131-like isoform X1. (1608 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
LGALS9Galectin. (356 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
CBLBE3 ubiquitin-protein ligase CBL-B. (983 aa)
DLG2Disks large homolog 2 isoform X1. (994 aa)
LRRC32Leucine-rich repeat-containing protein 32 isoform X1. (676 aa)
RASSF5Ras association domain-containing protein 5 isoform X1. (422 aa)
IL10Interleukin-10. (178 aa)
BLKTyrosine-protein kinase. (501 aa)
TSPAN32Tetraspanin-32 isoform X1; Belongs to the tetraspanin (TM4SF) family. (571 aa)
DLG5Disks large homolog 5 isoform X1; Belongs to the MAGUK family. (1980 aa)
VSIRV-type immunoglobulin domain-containing suppressor of T-cell activation. (311 aa)
NDFIP1NEDD4 family-interacting protein 1. (221 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (380 aa)
LOC111182867CMRF35-like molecule 8 isoform X1. (313 aa)
TYROBPTYRO protein tyrosine kinase-binding protein isoform X1. (126 aa)
FOXJ1Forkhead box protein J1. (422 aa)
GPNMBTransmembrane glycoprotein NMB. (553 aa)
TNFRSF21Tumor necrosis factor receptor superfamily member 21 isoform X3. (701 aa)
IL4I1L-amino-acid oxidase isoform X1. (653 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
IL20RBInterleukin-20 receptor subunit beta isoform X1. (342 aa)
LRRC1Leucine-rich repeat-containing protein 1. (395 aa)
BTKTyrosine-protein kinase. (687 aa)
LOC111178657Leucine-rich repeat-containing protein 1-like isoform X1. (174 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
PDCD1LG2Programmed cell death 1 ligand 2 isoform X1. (337 aa)
LOC111175407Amine oxidase. (524 aa)
IDO1Indoleamine 2,3-dioxygenase 1 isoform X1. (410 aa)
CD274Programmed cell death 1 ligand 1 isoform X2. (312 aa)
ARG2Arginase. (354 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
CTLA4Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (408 aa)
MARCH7E3 ubiquitin-protein ligase MARCH7 isoform X1. (717 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
MAD1L1Mitotic spindle assembly checkpoint protein MAD1 isoform X2. (735 aa)
RC3H1Roquin-1 isoform X1. (1135 aa)
CD86T-lymphocyte activation antigen CD86 isoform X1. (344 aa)
SOX11Transcription factor SOX. (454 aa)
TNFRSF13BTumor necrosis factor receptor superfamily member 13B isoform X1. (284 aa)
FOXP3Forkhead box protein P3. (431 aa)
VSIG4V-set and immunoglobulin domain-containing protein 4. (399 aa)
ZBTB7BZinc finger and BTB domain-containing protein 7B. (541 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
CRTAMCytotoxic and regulatory T-cell molecule isoform X1. (391 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
PAWRPRKC apoptosis WT1 regulator protein. (345 aa)
LYNTyrosine-protein kinase. (518 aa)
PKN1Serine/threonine-protein kinase N1 isoform X1. (950 aa)
LOC111166170C-type lectin domain family 4 member G-like isoform X1. (313 aa)
PLA2G2DPhospholipase A(2). (161 aa)
GLMNGlomulin. (592 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
PLA2G2FPhospholipase A(2). (300 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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