STRINGSTRING
AGTR1 AGTR1 LOC111163175 LOC111163175 B4GALT1 B4GALT1 NOG NOG SFN SFN KDF1 KDF1 F3 F3 XBP1 XBP1 PRKD1 PRKD1 TGM1 TGM1 MTSS1 MTSS1 MYC MYC CDKN2B CDKN2B IFT74 IFT74 TBC1D31 TBC1D31 CCL5 CCL5 STXBP4 STXBP4 NOD2 NOD2 PTPRM PTPRM ATOH8 ATOH8 TINF2 TINF2 FGF10 FGF10 PTPRK PTPRK LRG1 LRG1 LOC111165935 LOC111165935 PRKDC PRKDC INTU INTU CASK CASK FGFR3 FGFR3 UHRF1 UHRF1 NGFR NGFR STAT5A STAT5A NR1D1 NR1D1 STAT3 STAT3 TNFAIP3 TNFAIP3 GPC3 GPC3 MED1 MED1 PTCH1 PTCH1 BMP2 BMP2 DRD2 DRD2 SNAI2 SNAI2 LOC111165909 LOC111165909 PYGO2 PYGO2 SAAL1 SAAL1 SIRT6 SIRT6 ERBB2 ERBB2 FLCN FLCN JAG1 JAG1 TGFA TGFA AR AR MYDGF MYDGF ATP5A1 ATP5A1 KDM5B KDM5B BMPR1A BMPR1A LOC111166328 LOC111166328 EGR3 EGR3 CTNNB1 CTNNB1 MMRN2 MMRN2 WNT3A WNT3A WDR13 WDR13 ECM1 ECM1 ODAM ODAM GDF2 GDF2 HRAS HRAS PLXNB3 PLXNB3 VIP VIP IL12B IL12B LOC111167918 LOC111167918 DEAF1 DEAF1 EAF2 EAF2 WDR48 WDR48 YAP1 YAP1 AIMP1 AIMP1 PHOX2B PHOX2B FGFBP1 FGFBP1 BMPR2 BMPR2 LOC111170002 LOC111170002 PTPRN PTPRN ZNF304 ZNF304 COL4A3 COL4A3 LOC111171320 LOC111171320 ITGA4 ITGA4 STAT1 STAT1 FGFR2 FGFR2 DLG1 DLG1 PAX2 PAX2 NKX2-3 NKX2-3 KDR KDR SGPP2 SGPP2 ALOX5 ALOX5 LOC111169978 LOC111169978 GRN GRN BMP4 BMP4 SIX4 SIX4 STK11 STK11 HMX2 HMX2 CLDN1 CLDN1 SFRP1 SFRP1 FRS2 FRS2 MAGED1 MAGED1 ZNF703 ZNF703 FLT4 FLT4 KRT4 KRT4 TCF7L2 TCF7L2 SAV1 SAV1 SIX1 SIX1 VEGFC VEGFC HES1 HES1 FZD7 FZD7 MST1 MST1 HTR2B HTR2B CCR3 CCR3 SYNJ2BP SYNJ2BP SP1 SP1 SCG2 SCG2 VDR VDR NKX2-8 NKX2-8 PDX1 PDX1 WNT5A WNT5A FGF9 FGF9 FGFR1 FGFR1 XDH XDH HYAL1 HYAL1 FLT1 FLT1 IFT80 IFT80 TP63 TP63 WNT10B WNT10B ZFP36L1 ZFP36L1 TIE1 TIE1 CNMD CNMD JUN JUN VASH1 VASH1 IRS2 IRS2 RLN1 RLN1 IL26 IL26 NFIB NFIB PGF PGF AGAP2 AGAP2 GLI1 GLI1 MTA3 MTA3 SHH SHH NR4A1 NR4A1 ACVRL1 ACVRL1 BCL11B BCL11B EGFL7 EGFL7 PHB2 PHB2 PDCD10 PDCD10 NRARP NRARP IL12A IL12A FOXE3 FOXE3 KLF9 KLF9 AKT3 AKT3 ST8SIA1 ST8SIA1 FMC1 FMC1 PTN PTN TGFB2 TGFB2 BRCA2 BRCA2 JCAD JCAD TACSTD2 TACSTD2 TRIM24 TRIM24 SMO SMO HLX HLX ALDH1A2 ALDH1A2 VEGFA VEGFA BMP5 BMP5 LOC111177240 LOC111177240 PPARD PPARD RUNX2 RUNX2 PKHD1 PKHD1 CDH13 CDH13 CDKN1B CDKN1B PDCD6 PDCD6 HSF4 HSF4 NOTCH1 NOTCH1 DBH DBH SMAD3 SMAD3 DAB2IP DAB2IP ROBO1 ROBO1 CDH3 CDH3 ESRP2 ESRP2 CDC73 CDC73 DUSP10 DUSP10 TNMD TNMD CAV1 CAV1 CAV2 CAV2 FUT1 FUT1 GATA3 GATA3 PRKD2 PRKD2 ZEB1 ZEB1 ZFP36 ZFP36 CDK6 CDK6 LOC111180037 LOC111180037 APELA APELA SERPINB5 SERPINB5 FUT2 FUT2 C5AR1 C5AR1 C5AR2 C5AR2 EMC10 EMC10 A4GNT A4GNT WNT2 WNT2 HOXA5 HOXA5 TGFB1 TGFB1 BMP6 BMP6 FA2H FA2H PAX6 PAX6 DLL4 DLL4 MARVELD3 MARVELD3 LOC111181112 LOC111181112 OSR2 OSR2 NUPR1 NUPR1 PROK1 PROK1 NOTCH2 NOTCH2 NRAS NRAS CCL26 CCL26 ITGB3 ITGB3 STK3 STK3 ZNF580 ZNF580 LOC111182889 LOC111182889 DLX5 DLX5 KRIT1 KRIT1 HPN HPN LEP LEP RREB1 RREB1 PRKCA PRKCA CDKN1C CDKN1C DLX6 DLX6 BIRC5 BIRC5 MCC MCC FGF7 FGF7 LIMS2 LIMS2 THBS1 THBS1 SIRT1 SIRT1 OVOL1 OVOL1 CCL24 CCL24 CCND1 CCND1 MEF2C MEF2C FGF1 FGF1 PPP1R16B PPP1R16B APOH APOH THBS4 THBS4 SRSF6 SRSF6 CD109 CD109 VASH2 VASH2 LOC111184719 LOC111184719 PROX1 PROX1 DLG2 DLG2 BAD BAD VEGFB VEGFB APLNR APLNR STK4 STK4 IFT52 IFT52 AGGF1 AGGF1 GDF5 GDF5 IFT57 IFT57 NKX2-6 NKX2-6 EYA1 EYA1 PEX2 PEX2 PDGFB PDGFB EGFR EGFR LOC111185731 LOC111185731 SERPINF1 SERPINF1 LOC111184716 LOC111184716 LOC111185794 LOC111185794 AQP11 AQP11 PDPK1 PDPK1 NKX3-1 NKX3-1 HES5 HES5 SULF1 SULF1 NF1 NF1 LAMA5 LAMA5 NR2F2 NR2F2 RTN4 RTN4 EPGN EPGN IGF1 IGF1 TGFBR1 TGFBR1 PIK3CD PIK3CD PDCL3 PDCL3 SFRP2 SFRP2 HMOX1 HMOX1 Ob Ob TNF TNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGTR1Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC111163175Cyclin-dependent kinase inhibitor 2A-like. (152 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (402 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (292 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (910 aa)
TGM1Protein-glutamine gamma-glutamyltransferase K isoform X2. (849 aa)
MTSS1Metastasis suppressor protein 1 isoform X1. (762 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
CDKN2BCyclin-dependent kinase 4 inhibitor B. (131 aa)
IFT74Intraflagellar transport protein 74 homolog isoform X1. (600 aa)
TBC1D31TBC1 domain family member 31 isoform X1. (1073 aa)
CCL5C-C motif chemokine. (91 aa)
STXBP4Syntaxin-binding protein 4 isoform X1. (558 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa)
PTPRMReceptor-type tyrosine-protein phosphatase mu isoform X2. (1531 aa)
ATOH8Protein atonal homolog 8 isoform X1. (354 aa)
TINF2TERF1-interacting nuclear factor 2 isoform X1. (477 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
PTPRKReceptor-type tyrosine-protein phosphatase kappa isoform X1. (1485 aa)
LRG1Leucine-rich alpha-2-glycoprotein isoform X1. (354 aa)
LOC111165935Ras-like protein isoform X1. (285 aa)
PRKDCDNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family. (4131 aa)
INTUProtein inturned isoform X1. (934 aa)
CASKPeripheral plasma membrane protein CASK isoform X1; Belongs to the MAGUK family. (926 aa)
FGFR3Fibroblast growth factor receptor. (805 aa)
UHRF1E3 ubiquitin-protein ligase UHRF1 isoform X1. (790 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
STAT5ASignal transducer and activator of transcription. (818 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (785 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
PTCH1Protein patched homolog 1 isoform X1. (1447 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
LOC111165909LOW QUALITY PROTEIN: phosducin-like protein 3. (237 aa)
PYGO2LOW QUALITY PROTEIN: pygopus homolog 2. (406 aa)
SAAL1Protein SAAL1 isoform X1. (474 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6 isoform X3. (375 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
FLCNFolliculin isoform X1. (591 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1221 aa)
TGFAProtransforming growth factor alpha isoform X1. (176 aa)
ARAndrogen receptor. (893 aa)
MYDGFMyeloid-derived growth factor isoform X1. (175 aa)
ATP5A1ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
KDM5BLysine-specific demethylase 5B. (1539 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC111166328Nucleoside diphosphate kinase. (152 aa)
EGR3Early growth response protein 3 isoform X1. (387 aa)
CTNNB1Catenin beta-1. (781 aa)
MMRN2Multimerin-2 isoform X1. (935 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
WDR13WD repeat-containing protein 13 isoform X1. (485 aa)
ECM1Extracellular matrix protein 1 isoform X1. (544 aa)
ODAMLOW QUALITY PROTEIN: odontogenic ameloblast-associated protein. (281 aa)
GDF2Growth/differentiation factor 2. (431 aa)
HRASGTPase HRas isoform X1. (189 aa)
PLXNB3plexin-B3 isoform X1. (1986 aa)
VIPVIP peptides isoform X1. (170 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
LOC111167918LOW QUALITY PROTEIN: gastrokine-3-like. (204 aa)
DEAF1Deformed epidermal autoregulatory factor 1 homolog isoform X1. (565 aa)
EAF2ELL-associated factor 2. (264 aa)
WDR48WD repeat-containing protein 48. (677 aa)
YAP1Transcriptional coactivator YAP1 isoform X1. (511 aa)
AIMP1Aminoacyl tRNA synthase complex-interacting multifunctional protein 1. (321 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (311 aa)
FGFBP1Fibroblast growth factor-binding protein 1. (237 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
LOC111170002Zinc finger protein 304-like. (660 aa)
PTPRNReceptor-type tyrosine-protein phosphatase-like N isoform X1. (979 aa)
ZNF304Zinc finger protein 304. (661 aa)
COL4A3Collagen alpha-3(IV) chain. (1670 aa)
LOC111171320Mucin-16-like. (855 aa)
ITGA4Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa)
STAT1Signal transducer and activator of transcription. (749 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
PAX2Paired box protein Pax-2 isoform X1. (432 aa)
NKX2-3Homeobox protein Nkx-2.3. (366 aa)
KDRVascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (399 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
LOC111169978Von Hippel-Lindau disease tumor suppressor. (166 aa)
GRNGranulins isoform X1. (587 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (408 aa)
SIX4Homeobox protein SIX4 isoform X1. (790 aa)
STK11Serine/threonine-protein kinase STK11 isoform X1. (544 aa)
HMX2Homeobox protein HMX2. (273 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
SFRP1Secreted frizzled-related protein 1. (308 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
MAGED1Melanoma-associated antigen D1 isoform X1. (841 aa)
ZNF703Zinc finger protein 703. (585 aa)
FLT4Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
KRT4Keratin, type II cytoskeletal 4; Belongs to the intermediate filament family. (519 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (668 aa)
SAV1Protein salvador homolog 1. (385 aa)
SIX1Homeobox protein SIX1. (284 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
HES1Transcription factor HES-1. (280 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
MST1Hepatocyte growth factor-like protein isoform X1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
HTR2B5-hydroxytryptamine receptor 2B. (490 aa)
CCR3C-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (358 aa)
SYNJ2BPSynaptojanin-2-binding protein isoform X1. (150 aa)
SP1Transcription factor Sp1. (786 aa)
SCG2Secretogranin-2. (615 aa)
VDRVitamin D3 receptor isoform X1. (503 aa)
NKX2-8Homeobox protein Nkx-2.8. (235 aa)
PDX1Pancreas/duodenum homeobox protein 1. (289 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGFR1Fibroblast growth factor receptor. (823 aa)
XDHXanthine dehydrogenase/oxidase isoform X1. (1334 aa)
HYAL1Hyaluronidase. (448 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
IFT80Intraflagellar transport protein 80 homolog isoform X1. (777 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
ZFP36L1mRNA decay activator protein ZFP36L1. (338 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
CNMDLeukocyte cell-derived chemotaxin 1 isoform X1. (335 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (343 aa)
VASH1Vasohibin-1 isoform X1. (387 aa)
IRS2Insulin receptor substrate 2. (1347 aa)
RLN1Prorelaxin H1. (183 aa)
IL26Interleukin-26. (171 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
PGFPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa)
AGAP2arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1. (1192 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
MTA3Metastasis-associated protein MTA3 isoform X1. (604 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (593 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
BCL11BB-cell lymphoma/leukemia 11B isoform X1. (903 aa)
EGFL7Epidermal growth factor-like protein 7 isoform X1. (274 aa)
PHB2Prohibitin. (299 aa)
PDCD10Programmed cell death protein 10. (212 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
FOXE3Forkhead box protein E3. (317 aa)
KLF9Krueppel-like factor 9. (244 aa)
AKT3Non-specific serine/threonine protein kinase. (541 aa)
ST8SIA1alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family. (356 aa)
FMC1Protein FMC1 homolog. (113 aa)
PTNPleiotrophin isoform X1. (168 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
BRCA2Breast cancer type 2 susceptibility protein. (3435 aa)
JCADJunctional protein associated with coronary artery disease. (1281 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (323 aa)
TRIM24Transcription intermediary factor 1-alpha isoform X1. (1050 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
HLXH2.0-like homeobox protein. (488 aa)
ALDH1A2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
BMP5Bone morphogenetic protein 5 isoform X1. (454 aa)
LOC111177240LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 6-like. (346 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform X1. (441 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (524 aa)
PKHD1Fibrocystin isoform X1. (4074 aa)
CDH13Cadherin-13 isoform X1. (713 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
PDCD6Programmed cell death protein 6 isoform X1. (189 aa)
HSF4LOW QUALITY PROTEIN: heat shock factor protein 4. (490 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
DBHDopamine beta-hydroxylase. (610 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
DAB2IPDisabled homolog 2-interacting protein isoform X1. (1193 aa)
ROBO1Roundabout homolog 1 isoform X1. (1685 aa)
CDH3Cadherin-3 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (834 aa)
ESRP2Epithelial splicing regulatory protein 2 isoform X3. (717 aa)
CDC73Parafibromin. (531 aa)
DUSP10Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
TNMDTenomodulin. (317 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (536 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
ZEB1Zinc finger E-box-binding homeobox 1 isoform X2. (1110 aa)
ZFP36mRNA decay activator protein ZFP36. (325 aa)
CDK6Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. (326 aa)
LOC111180037Methylosome protein 50-like. (290 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
SERPINB5Serpin B5; Belongs to the serpin family. (375 aa)
FUT2L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (344 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (424 aa)
C5AR2C5a anaphylatoxin chemotactic receptor 2 isoform X1. (343 aa)
EMC10ER membrane protein complex subunit 10 isoform X1. (260 aa)
A4GNTalpha-1,4-N-acetylglucosaminyltransferase. (341 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
HOXA5Homeobox protein Hox-A5. (381 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
BMP6Bone morphogenetic protein 6. (496 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (396 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
MARVELD3MARVEL domain-containing protein 3. (384 aa)
LOC111181112Uncharacterized protein LOC111181112. (257 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
NUPR1Nuclear protein 1. (82 aa)
PROK1Prokineticin-1. (105 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
NRASGTPase NRas. (189 aa)
CCL26C-C motif chemokine 26. (94 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
STK3Serine/threonine-protein kinase 3. (491 aa)
ZNF580Zinc finger protein 580 isoform X1. (182 aa)
LOC111182889LOW QUALITY PROTEIN: transcription factor SOX-9-like. (510 aa)
DLX5Homeobox protein DLX-5. (289 aa)
KRIT1Krev interaction trapped protein 1 isoform X1. (736 aa)
HPNSerine protease hepsin isoform X1; Belongs to the peptidase S1 family. (599 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
RREB1Ras-responsive element-binding protein 1 isoform X1. (1760 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
CDKN1CCyclin-dependent kinase inhibitor 1C. (257 aa)
DLX6Homeobox protein DLX-6. (296 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (142 aa)
MCCColorectal mutant cancer protein isoform X1. (1049 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (366 aa)
THBS1Thrombospondin-1. (1170 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (735 aa)
OVOL1Putative transcription factor Ovo-like 1. (267 aa)
CCL24C-C motif chemokine 24. (119 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X6. (483 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa)
PPP1R16BProtein phosphatase 1 regulatory inhibitor subunit 16B. (568 aa)
APOHBeta-2-glycoprotein 1 isoform X1. (345 aa)
THBS4Thrombospondin-4. (961 aa)
SRSF6Serine/arginine-rich splicing factor 6 isoform X1. (345 aa)
CD109CD109 antigen isoform X1. (1440 aa)
VASH2Vasohibin-2 isoform X1. (355 aa)
LOC111184719Interferon regulatory factor 6 isoform X1. (467 aa)
PROX1Prospero homeobox protein 1 isoform X1. (738 aa)
DLG2Disks large homolog 2 isoform X1. (994 aa)
BADBcl2-associated agonist of cell death. (168 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (209 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (487 aa)
IFT52Intraflagellar transport protein 52 homolog isoform X1. (446 aa)
AGGF1Angiogenic factor with G patch and FHA domains 1. (714 aa)
GDF5Growth/differentiation factor 5. (499 aa)
IFT57Intraflagellar transport protein 57 homolog isoform X1. (427 aa)
NKX2-6Homeobox protein Nkx-2.6. (300 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (589 aa)
PEX2Peroxisome biogenesis factor 2. (336 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (278 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
LOC111185731C-C motif chemokine. (99 aa)
SERPINF1Pigment epithelium-derived factor isoform X1; Belongs to the serpin family. (416 aa)
LOC111184716Interferon regulatory factor 6 isoform X2. (485 aa)
LOC111185794C-C motif chemokine. (97 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
NKX3-1Homeobox protein Nkx-3.1. (241 aa)
HES5Transcription factor HES-5 isoform X1. (205 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (882 aa)
NF1Neurofibromin isoform X1. (2873 aa)
LAMA5Laminin subunit alpha-5. (3687 aa)
NR2F2COUP transcription factor 2 isoform X1. (414 aa)
RTN4Reticulon. (1192 aa)
EPGNEpigen. (153 aa)
IGF1Insulin-like growth factor I isoform X1. (186 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
PDCL3Phosducin-like protein 3. (240 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
ObLeptin isoform X1. (167 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (30%) [HD]