STRINGSTRING
TUB TUB DOCK2 DOCK2 IL2RG IL2RG IL2RB IL2RB APPL2 APPL2 MERTK MERTK IL15 IL15 TNF TNF SIRPA SIRPA CD47 CD47 SFTPD SFTPD LOC111184361 LOC111184361 LOC111183561 LOC111183561 CD300LF CD300LF PYCARD PYCARD TREM2 TREM2 TULP1 TULP1 PLCG2 PLCG2 LOC111177076 LOC111177076 LOC111179403 LOC111179403 GAS6 GAS6 CAMK1D CAMK1D PTX3 PTX3 LOC111176754 LOC111176754 AHSG AHSG NCKAP1L NCKAP1L C2 C2 MBL2 MBL2 LMAN2 LMAN2 ABCA7 ABCA7 LYAR LYAR SLC11A1 SLC11A1 CALR CALR MFGE8 MFGE8 BCR BCR FCN3 FCN3 PLA2G5 PLA2G5 F2RL1 F2RL1 NOD2 NOD2 COLEC10 COLEC10 FCER1G FCER1G APOA1 APOA1 APOA2 APOA2 PTPRC PTPRC COLEC11 COLEC11 AZU1 AZU1 IL1B IL1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TUBTubby-like protein; Belongs to the TUB family. (511 aa)
DOCK2Dedicator of cytokinesis protein 2 isoform X1; Belongs to the DOCK family. (1828 aa)
IL2RGCytokine receptor common subunit gamma isoform X1. (381 aa)
IL2RBInterleukin-2 receptor subunit beta isoform X1. (595 aa)
APPL2DCC-interacting protein 13-beta isoform X2. (661 aa)
MERTKTyrosine-protein kinase Mer. (999 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (180 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
SIRPATyrosine-protein phosphatase non-receptor type substrate 1 isoform X1. (504 aa)
CD47Leukocyte surface antigen CD47 isoform X1. (329 aa)
SFTPDPulmonary surfactant-associated protein D. (375 aa)
LOC111184361Signal-regulatory protein beta-1-like isoform X1. (412 aa)
LOC111183561Mannose-binding protein A-like isoform X1. (265 aa)
CD300LFCMRF35-like molecule 1 isoform X1. (310 aa)
PYCARDApoptosis-associated speck-like protein containing a CARD. (195 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (294 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (537 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
LOC111177076Ficolin-2-like isoform X1. (326 aa)
LOC111179403Cytochrome b-245 light chain isoform X1. (202 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
CAMK1DCalcium/calmodulin-dependent protein kinase type 1D isoform X1. (435 aa)
PTX3Pentraxin-related protein PTX3. (382 aa)
LOC111176754C-type lectin domain family 7 member A-like isoform X1. (244 aa)
AHSGalpha-2-HS-glycoprotein. (360 aa)
NCKAP1LNck-associated protein 1-like isoform X1. (1156 aa)
C2Complement C2 isoform X1; Belongs to the peptidase S1 family. (751 aa)
MBL2LOW QUALITY PROTEIN: mannose-binding protein C. (244 aa)
LMAN2Vesicular integral-membrane protein VIP36. (363 aa)
ABCA7LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 7. (2103 aa)
LYARCell growth-regulating nucleolar protein. (389 aa)
SLC11A1Natural resistance-associated macrophage protein 1 isoform X1. (546 aa)
CALRCalreticulin. (417 aa)
MFGE8Lactadherin. (431 aa)
BCRBreakpoint cluster region protein isoform X1. (1275 aa)
FCN3LOW QUALITY PROTEIN: ficolin-3. (270 aa)
PLA2G5Phospholipase A(2). (156 aa)
F2RL1Proteinase-activated receptor 2. (315 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa)
COLEC10Collectin-10 isoform X1. (277 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
APOA1Apolipoprotein A-I. (265 aa)
APOA2Apolipoprotein A-II. (103 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
COLEC11Collectin-11. (267 aa)
AZU1Azurocidin. (252 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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