STRINGSTRING
HS3ST5 HS3ST5 FGG FGG C1QTNF6 C1QTNF6 ANXA5 ANXA5 FGB FGB THBD THBD SH2B3 SH2B3 PDGFB PDGFB ALOX12 ALOX12 F2 F2 PROC PROC PROCR PROCR APOH APOH SERPING1 SERPING1 C1QTNF1 C1QTNF1 PLAU PLAU ADTRP ADTRP ADAMTS18 ADAMTS18 PROS1 PROS1 PRKCD PRKCD PRKG1 PRKG1 CPB2 CPB2 KNG1 KNG1 TFPI TFPI LOC111173428 LOC111173428 SERPINE2 SERPINE2 F12 F12 PDGFRA PDGFRA PDGFA PDGFA PLG PLG UBASH3B UBASH3B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HS3ST5Sulfotransferase; Belongs to the sulfotransferase 1 family. (345 aa)
FGGFibrinogen gamma chain isoform X1. (445 aa)
C1QTNF6Complement C1q tumor necrosis factor-related protein 6. (266 aa)
ANXA5Annexin. (370 aa)
FGBFibrinogen beta chain isoform X1. (495 aa)
THBDThrombomodulin. (584 aa)
SH2B3SH2B adapter protein 3 isoform X1. (618 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (278 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
PROCVitamin K-dependent protein C. (480 aa)
PROCREndothelial protein C receptor. (242 aa)
APOHBeta-2-glycoprotein 1 isoform X1. (345 aa)
SERPING1Plasma protease C1 inhibitor; Belongs to the serpin family. (471 aa)
C1QTNF1LOW QUALITY PROTEIN: complement C1q tumor necrosis factor-related protein 1. (279 aa)
PLAUUrokinase-type plasminogen activator. (431 aa)
ADTRPAndrogen-dependent TFPI-regulating protein isoform X1. (230 aa)
ADAMTS18A disintegrin and metalloproteinase with thrombospondin motifs 18 isoform X1. (1227 aa)
PROS1Vitamin K-dependent protein S. (675 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (733 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
CPB2Carboxypeptidase B2. (423 aa)
KNG1Kininogen-1 isoform X1. (627 aa)
TFPITissue factor pathway inhibitor isoform X1. (307 aa)
LOC111173428Coagulation factor XI; Belongs to the peptidase S1 family. (633 aa)
SERPINE2Glia-derived nexin isoform X2; Belongs to the serpin family. (397 aa)
F12LOW QUALITY PROTEIN: coagulation factor XII. (650 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (196 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (812 aa)
UBASH3BUbiquitin-associated and SH3 domain-containing protein B isoform X1. (649 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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