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| | EPCAM | Epithelial cell adhesion molecule. (314 aa) |
| | CHMP5 | Charged multivesicular body protein 5. (219 aa) |
| | UBAP2 | Ubiquitin-associated protein 2 isoform X1. (1175 aa) |
| | ARVCF | Armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X1. (960 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type 2 isoform X3. (474 aa) |
| | ITGB1BP1 | Integrin beta-1-binding protein 1 isoform X1. (206 aa) |
| | TJP1 | Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family. (1914 aa) |
| | ITGA9 | Integrin alpha-9; Belongs to the integrin alpha chain family. (1035 aa) |
| | PTPRM | Receptor-type tyrosine-protein phosphatase mu isoform X2. (1531 aa) |
| | WISP3 | WNT1-inducible-signaling pathway protein 3. (210 aa) |
| | LOC111165042 | Protein NDRG1. (374 aa) |
| | LOC111165062 | WNT1-inducible-signaling pathway protein 1-like. (398 aa) |
| | FERMT1 | Fermitin family homolog 1. (677 aa) |
| | NOV | Protein NOV homolog. (359 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa) |
| | CTGF | Connective tissue growth factor isoform X1. (349 aa) |
| | ICAM3 | Intercellular adhesion molecule 3 isoform X1. (545 aa) |
| | DSCAM | Down syndrome cell adhesion molecule isoform X2. (1577 aa) |
| | S1PR2 | Sphingosine 1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | LGALS8 | Galectin. (317 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (536 aa) |
| | CDH24 | Cadherin-24 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (806 aa) |
| | ICAM4 | Intercellular adhesion molecule 4. (334 aa) |
| | LOC111166071 | Phospholipid phosphatase 3-like. (264 aa) |
| | JUP | Junction plakoglobin. (744 aa) |
| | CDH8 | Cadherin-8 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (715 aa) |
| | CDH11 | Cadherin-11 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (796 aa) |
| | COMP | Cartilage oligomeric matrix protein. (756 aa) |
| | CTNNA2 | Catenin alpha-2. (865 aa) |
| | UTRN | Utrophin isoform X7. (3432 aa) |
| | KIRREL3 | Kin of IRRE-like protein 3 isoform X1. (778 aa) |
| | JAML | Junctional adhesion molecule-like. (383 aa) |
| | ADGRL1 | Adhesion G protein-coupled receptor L1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (1474 aa) |
| | PHLDB1 | Pleckstrin homology-like domain family B member 1 isoform X5. (1504 aa) |
| | ICAM5 | Intercellular adhesion molecule 5 isoform X1. (922 aa) |
| | CADM1 | Cell adhesion molecule 1 isoform X1. (469 aa) |
| | ROBO3 | Roundabout homolog 3. (1374 aa) |
| | EZR | Ezrin. (586 aa) |
| | TAGLN2 | Transgelin; Belongs to the calponin family. (199 aa) |
| | ESAM | LOW QUALITY PROTEIN: endothelial cell-selective adhesion molecule. (396 aa) |
| | MCAM | Cell surface glycoprotein MUC18 isoform X1. (638 aa) |
| | ITGA3 | Integrin alpha-3 isoform X1; Belongs to the integrin alpha chain family. (1068 aa) |
| | JAM3 | Junctional adhesion molecule C. (301 aa) |
| | S1PR3 | Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | AFDN | Afadin isoform X1. (1794 aa) |
| | NECTIN1 | Nectin-1. (416 aa) |
| | TNN | tenascin-N. (1296 aa) |
| | VSIG2 | V-set and immunoglobulin domain-containing protein 2 isoform X1. (339 aa) |
| | CPE | Carboxypeptidase E. (475 aa) |
| | TENM1 | Teneurin-1 isoform X1. (2659 aa) |
| | RDX | Radixin isoform X2. (604 aa) |
| | TJP3 | Tight junction protein ZO-3 isoform X1; Belongs to the MAGUK family. (922 aa) |
| | LRRC59 | Leucine-rich repeat-containing protein 59 isoform X1. (334 aa) |
| | CALR | Calreticulin. (417 aa) |
| | MICALL2 | MICAL-like protein 2 isoform X1. (953 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | NCAM1 | Neural cell adhesion molecule 1 isoform X1. (1147 aa) |
| | MFGE8 | Lactadherin. (431 aa) |
| | KIRREL1 | Kin of IRRE-like protein 1 isoform X1. (773 aa) |
| | F11R | Junctional adhesion molecule A. (299 aa) |
| | ADAM15 | Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (866 aa) |
| | DCHS1 | Protocadherin-16. (3294 aa) |
| | IGSF9 | Protein turtle homolog A. (1176 aa) |
| | NINJ1 | Ninjurin-1 isoform X1. (156 aa) |
| | CDH6 | Cadherin-6; Cadherins are calcium-dependent cell adhesion proteins. (790 aa) |
| | PKP1 | Plakophilin-1 isoform X2. (727 aa) |
| | THY1 | Thy-1 membrane glycoprotein. (161 aa) |
| | TSPAN4 | Tetraspanin. (311 aa) |
| | MSN | Moesin isoform X1. (579 aa) |
| | ITGA2B | Integrin alpha-IIb; Belongs to the integrin alpha chain family. (1034 aa) |
| | CD151 | Tetraspanin. (253 aa) |
| | SYK | Tyrosine-protein kinase. (626 aa) |
| | CDHR5 | Cadherin-related family member 5 isoform X3. (674 aa) |
| | PLXNB3 | plexin-B3 isoform X1. (1986 aa) |
| | RPSA | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa) |
| | LOC111171390 | LOW QUALITY PROTEIN: neuroligin-2-like. (304 aa) |
| | L1CAM | Neural cell adhesion molecule L1. (1257 aa) |
| | LOC111171406 | Neuroligin-2. (301 aa) |
| | BZW1 | Basic leucine zipper and W2 domain-containing protein 1 isoform X1. (419 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | GLDN | Gliomedin. (548 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (800 aa) |
| | COL4A3 | Collagen alpha-3(IV) chain. (1670 aa) |
| | NPNT | Nephronectin isoform X3. (595 aa) |
| | ITGA4 | Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa) |
| | ITGAV | Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa) |
| | COL3A1 | Collagen alpha-1(III) chain. (1464 aa) |
| | PKP3 | Plakophilin-3 isoform X1. (811 aa) |
| | GFRA1 | GDNF family receptor alpha; Belongs to the GDNFR family. (468 aa) |
| | KDR | Vascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | CXCL12 | Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa) |
| | CDHR2 | Cadherin-related family member 2. (1311 aa) |
| | SHTN1 | Shootin-1 isoform X1. (631 aa) |
| | CDH22 | Cadherin-22 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (832 aa) |
| | PROM1 | Prominin-1 isoform X1. (887 aa) |
| | FAP | Prolyl endopeptidase FAP; Belongs to the peptidase S9B family. (783 aa) |
| | MADCAM1 | Mucosal addressin cell adhesion molecule 1. (406 aa) |
| | ACTN1 | Alpha-actinin-1 isoform X2. (914 aa) |
| | LOC111171048 | Neuroligin-2-like. (664 aa) |
| | LOC111171171 | Integrin alpha-M-like. (296 aa) |
| | CNTN4 | Contactin-4 isoform X1. (1026 aa) |
| | ITGB7 | Integrin beta; Belongs to the integrin beta chain family. (819 aa) |
| | CNTN3 | Contactin-3 isoform X1. (1027 aa) |
| | FN1 | Fibronectin isoform X5. (2478 aa) |
| | NISCH | Nischarin isoform X1. (1513 aa) |
| | ITGB6 | Integrin beta; Belongs to the integrin beta chain family. (808 aa) |
| | ADAM8 | Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa) |
| | FERMT2 | Fermitin family homolog 2 isoform X2. (691 aa) |
| | JAM2 | Junctional adhesion molecule B isoform X1. (350 aa) |
| | POSTN | Periostin isoform X6. (836 aa) |
| | PTPRB | Receptor-type tyrosine-protein phosphatase beta isoform X1. (2213 aa) |
| | CXADR | Coxsackievirus and adenovirus receptor isoform X1. (365 aa) |
| | TRPC4 | Short transient receptor potential channel 4; Belongs to the transient receptor (TC 1.A.4) family. (976 aa) |
| | ITGA7 | Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1141 aa) |
| | PKP4 | Plakophilin-4 isoform X1. (1193 aa) |
| | ITGA6 | Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1091 aa) |
| | CNTN1 | Contactin-1 isoform X1. (1018 aa) |
| | CNTN6 | Contactin-6. (956 aa) |
| | PTPRF | Receptor-type tyrosine-protein phosphatase F isoform X1. (1917 aa) |
| | ITGBL1 | Integrin beta-like protein 1. (400 aa) |
| | ADAM9 | Disintegrin and metalloproteinase domain-containing protein 9 isoform X1. (841 aa) |
| | TSPAN8 | Tetraspanin. (216 aa) |
| | NUMB | Protein numb homolog isoform X1. (653 aa) |
| | PLPP3 | Phospholipid phosphatase 3. (312 aa) |
| | LIMA1 | LIM domain and actin-binding protein 1 isoform X1. (766 aa) |
| | CHL1 | Neural cell adhesion molecule L1-like protein isoform X1. (1225 aa) |
| | COL16A1 | Collagen alpha-1(XVI) chain isoform X1. (1632 aa) |
| | ARGLU1 | Arginine and glutamate-rich protein 1. (273 aa) |
| | LAMB2 | Laminin subunit beta-2 isoform X1. (1812 aa) |
| | TJP2 | Tight junction protein ZO-2 isoform X2; Belongs to the MAGUK family. (1187 aa) |
| | TSPAN9 | Tetraspanin. (330 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | ITGA11 | Integrin alpha-11; Belongs to the integrin alpha chain family. (1188 aa) |
| | FBLN5 | Fibulin-5 isoform X1. (461 aa) |
| | EMILIN1 | EMILIN-1. (1015 aa) |
| | PTN | Pleiotrophin isoform X1. (168 aa) |
| | LCP1 | Plastin-2. (627 aa) |
| | TACSTD2 | Tumor-associated calcium signal transducer 2. (323 aa) |
| | PKP2 | Plakophilin-2 isoform X1. (826 aa) |
| | IGDCC3 | Immunoglobulin superfamily DCC subclass member 3. (800 aa) |
| | NPTN | Neuroplastin isoform X1. (398 aa) |
| | TSPAN11 | Tetraspanin. (359 aa) |
| | SEMA7A | semaphorin-7A; Belongs to the semaphorin family. (665 aa) |
| | ANGPTL3 | Angiopoietin-related protein 3. (460 aa) |
| | LOC111178591 | Cadherin-10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa) |
| | PTPRO | Receptor-type tyrosine-protein phosphatase O isoform X1. (1216 aa) |
| | LOC111178657 | Leucine-rich repeat-containing protein 1-like isoform X1. (174 aa) |
| | PPFIBP1 | Liprin-beta-1 isoform X1. (1036 aa) |
| | ITGA8 | Integrin alpha-8 isoform X1; Belongs to the integrin alpha chain family. (1062 aa) |
| | NRXN3 | Neurexin 3 isoform X15. (1679 aa) |
| | LRRC1 | Leucine-rich repeat-containing protein 1. (395 aa) |
| | LOC111178986 | LOW QUALITY PROTEIN: catenin alpha-1-like. (908 aa) |
| | IBSP | Bone sialoprotein 2. (317 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa) |
| | PTPRZ1 | Receptor-type tyrosine-protein phosphatase zeta isoform X1. (2321 aa) |
| | CTNND2 | Catenin delta-2 isoform X1. (1253 aa) |
| | CDH9 | Cadherin-9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa) |
| | VWF | Von Willebrand factor. (2806 aa) |
| | CYR61 | Protein CYR61. (382 aa) |
| | NEXN | Nexilin isoform X4. (673 aa) |
| | CDH13 | Cadherin-13 isoform X1. (713 aa) |
| | CDH18 | Cadherin-18 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (790 aa) |
| | CDH16 | Cadherin-16 isoform X1. (830 aa) |
| | ITGA10 | Integrin alpha-10; Belongs to the integrin alpha chain family. (1167 aa) |
| | CDH3 | Cadherin-3 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (834 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (798 aa) |
| | CTNNAL1 | Alpha-catulin isoform X1. (734 aa) |
| | CDH15 | LOW QUALITY PROTEIN: cadherin-15; Cadherins are calcium-dependent cell adhesion proteins. (793 aa) |
| | NPHS1 | Nephrin. (1270 aa) |
| | VCAM1 | Vascular cell adhesion protein 1. (739 aa) |
| | CDH12 | Cadherin-12 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (794 aa) |
| | IZUMO1 | Izumo sperm-egg fusion protein 1 isoform X1. (426 aa) |
| | CDH20 | Cadherin-20; Cadherins are calcium-dependent cell adhesion proteins. (801 aa) |
| | CDH5 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa) |
| | BCAM | Basal cell adhesion molecule. (628 aa) |
| | PTK7 | Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa) |
| | SPP1 | Osteopontin. (362 aa) |
| | LAMA3 | Laminin subunit alpha-3 isoform X3. (3335 aa) |
| | FRMD5 | FERM domain-containing protein 5. (570 aa) |
| | NECTIN2 | Nectin-2 isoform X1. (539 aa) |
| | PVR | Poliovirus receptor isoform X1. (415 aa) |
| | LRRC4C | Leucine-rich repeat-containing protein 4C. (640 aa) |
| | NUMBL | Numb-like protein isoform X1. (590 aa) |
| | DSP | Desmoplakin isoform X1. (2874 aa) |
| | DSG2 | Desmoglein-2. (1116 aa) |
| | NTNG1 | netrin-G1 isoform X1. (582 aa) |
| | CDH1 | Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa) |
| | CDH7 | Cadherin-7 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (869 aa) |
| | FXYD5 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (172 aa) |
| | CDH17 | Cadherin-17 isoform X1. (832 aa) |
| | BZW2 | Basic leucine zipper and W2 domain-containing protein 2. (419 aa) |
| | CD226 | CD226 antigen. (335 aa) |
| | CDH19 | Cadherin-19 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (770 aa) |
| | GPNMB | Transmembrane glycoprotein NMB. (553 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (789 aa) |
| | LOC111182106 | Integrin alpha-X-like isoform X1; Belongs to the integrin alpha chain family. (1210 aa) |
| | CD177 | CD177 antigen isoform X1. (443 aa) |
| | KIRREL2 | Kin of IRRE-like protein 2. (668 aa) |
| | ITGAM | Integrin alpha-M; Belongs to the integrin alpha chain family. (872 aa) |
| | CTNNA1 | Catenin alpha-1. (906 aa) |
| | UBFD1 | Ubiquitin domain-containing protein UBFD1 isoform X6. (319 aa) |
| | ICAM2 | Intercellular adhesion molecule 2 isoform X1. (292 aa) |
| | CDH2 | Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa) |
| | LOC111182617 | Intercellular adhesion molecule 5. (545 aa) |
| | ANXA7 | Annexin. (491 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) |
| | FBN1 | Fibrillin-1 isoform X1. (2871 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (767 aa) |
| | FERMT3 | Fermitin family homolog 3. (663 aa) |
| | THBS1 | Thrombospondin-1. (1170 aa) |
| | CTNNA3 | Catenin alpha-3. (944 aa) |
| | ITGAL | Integrin alpha-L; Belongs to the integrin alpha chain family. (1166 aa) |
| | MMP24 | Matrix metalloproteinase-24 isoform X1. (638 aa) |
| | IGF2 | Insulin-like growth factor II isoform X3. (237 aa) |
| | TGFBI | Transforming growth factor-beta-induced protein ig-h3. (683 aa) |
| | CTNND1 | Catenin delta-1 isoform X1. (961 aa) |
| | ITGB4 | Integrin beta. (1826 aa) |
| | P4HB | Protein disulfide-isomerase. (510 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa) |
| | THBS4 | Thrombospondin-4. (961 aa) |
| | TENM4 | Teneurin-4 isoform X1. (2864 aa) |
| | WISP2 | WNT1-inducible-signaling pathway protein 2. (250 aa) |
| | SRC | Tyrosine-protein kinase. (562 aa) |
| | LAMB1 | Laminin subunit beta-1. (1786 aa) |
| | NRCAM | Neuronal cell adhesion molecule isoform X10. (1212 aa) |
| | LOC111185338 | Palladin-like. (653 aa) |
| | LOC111184602 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (367 aa) |
| | LGALS12 | Galectin. (318 aa) |
| | PTPRT | Receptor-type tyrosine-protein phosphatase T isoform X1. (1461 aa) |
| | VSTM2L | V-set and transmembrane domain-containing protein 2-like protein. (205 aa) |
| | PALLD | Palladin isoform X1. (656 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | NFASC | Neurofascin isoform X3. (1359 aa) |
| | ITGAE | Integrin alpha-E; Belongs to the integrin alpha chain family. (1173 aa) |
| | NLGN2 | Neuroligin-2 isoform X1. (181 aa) |
| | CDC42EP1 | Cdc42 effector protein 1. (361 aa) |
| | VTN | Vitronectin. (565 aa) |
| | LAMA5 | Laminin subunit alpha-5. (3687 aa) |
| | GOLGA3 | Golgin subfamily A member 3 isoform X1. (1497 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa) |
| | EMB | Embigin. (329 aa) |
| | GLOD4 | Glyoxalase domain-containing protein 4. (298 aa) |
| | FGB | Fibrinogen beta chain isoform X1. (495 aa) |
| | PHLDB2 | Pleckstrin homology-like domain family B member 2 isoform X1. (1364 aa) |
| | FBLN1 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa) |
| | ITGB2 | Integrin beta. (769 aa) |
| | TXNDC9 | Thioredoxin domain-containing protein 9. (226 aa) |
| | CDH4 | Cadherin-4 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (914 aa) |
| | ESM1 | Endothelial cell-specific molecule 1. (184 aa) |
| | FGG | Fibrinogen gamma chain isoform X1. (445 aa) |
| | ITGA2 | Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa) |
| | ITGA1 | Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa) |
| | IGF1 | Insulin-like growth factor I isoform X1. (186 aa) |
| | NECTIN3 | Nectin-3 isoform X1. (549 aa) |
| | VSIG10 | V-set and immunoglobulin domain-containing protein 10 isoform X1. (537 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa) |
| | CD200 | OX-2 membrane glycoprotein. (267 aa) |
| | MYH9 | Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa) |
| | TLN1 | Talin-1. (2541 aa) |
| | TBC1D2 | TBC1 domain family member 2A isoform X1. (1029 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
