(21 nodes) Brown fat cell differentiation network (Delphinapterus leucas)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LAMA4	Laminin subunit alpha-4 isoform X1. (1824 aa)
	ZNF423	Zinc finger protein 423 isoform X2. (1224 aa)
	LRG1	Leucine-rich alpha-2-glycoprotein isoform X1. (354 aa)
	LOC111164929	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	ZNF516	Zinc finger protein 516 isoform X1. (1134 aa)
	DHRS7B	Dehydrogenase/reductase SDR family member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa)
	ARL4C	ADP-ribosylation factor-like protein 4C; Belongs to the small GTPase superfamily. Arf family. (192 aa)
	FFAR4	Free fatty acid receptor 4 isoform X3. (375 aa)
	ADRB1	Beta-1 adrenergic receptor. (470 aa)
	ADRB3	LOW QUALITY PROTEIN: beta-3 adrenergic receptor. (391 aa)
	ALDH6A1	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform X1. (537 aa)
	NUDT7	Peroxisomal coenzyme A diphosphatase NUDT7 isoform X1. (264 aa)
	ARL4A	ADP-ribosylation factor-like protein 4A. (200 aa)
	SH2B2	SH2B adapter protein 2 isoform X1. (703 aa)
	ADRB2	Beta-2 adrenergic receptor isoform X1. (400 aa)
	ADIG	Adipogenin. (79 aa)
	LAMB3	Laminin subunit beta-3. (1172 aa)
	SLC2A4	Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	PTGS2	Prostaglandin G/H synthase 2. (604 aa)
	CEBPB	CCAAT/enhancer-binding protein. (345 aa)
	PLAC8	Placenta-specific gene 8 protein. (113 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRB1	ADRB2	A0A2Y9MZC6	A0A2Y9PQW9	Beta-1 adrenergic receptor.	Beta-2 adrenergic receptor isoform X1.	0.981
ADRB1	ADRB3	A0A2Y9MZC6	A0A2Y9N6S8	Beta-1 adrenergic receptor.	LOW QUALITY PROTEIN: beta-3 adrenergic receptor.	0.977
ADRB2	ADRB1	A0A2Y9PQW9	A0A2Y9MZC6	Beta-2 adrenergic receptor isoform X1.	Beta-1 adrenergic receptor.	0.981
ADRB2	ADRB3	A0A2Y9PQW9	A0A2Y9N6S8	Beta-2 adrenergic receptor isoform X1.	LOW QUALITY PROTEIN: beta-3 adrenergic receptor.	0.977
ADRB3	ADRB1	A0A2Y9N6S8	A0A2Y9MZC6	LOW QUALITY PROTEIN: beta-3 adrenergic receptor.	Beta-1 adrenergic receptor.	0.977
ADRB3	ADRB2	A0A2Y9N6S8	A0A2Y9PQW9	LOW QUALITY PROTEIN: beta-3 adrenergic receptor.	Beta-2 adrenergic receptor isoform X1.	0.977
ADRB3	LOC111164929	A0A2Y9N6S8	A0A2Y9LUH8	LOW QUALITY PROTEIN: beta-3 adrenergic receptor.	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.434
ADRB3	SLC2A4	A0A2Y9N6S8	A0A2Y9Q0F1	LOW QUALITY PROTEIN: beta-3 adrenergic receptor.	Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.434
CEBPB	LOC111164929	A0A2Y9Q722	A0A2Y9LUH8	CCAAT/enhancer-binding protein.	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.611
CEBPB	PTGS2	A0A2Y9Q722	A0A2Y9Q0P2	CCAAT/enhancer-binding protein.	Prostaglandin G/H synthase 2.	0.446
CEBPB	SLC2A4	A0A2Y9Q722	A0A2Y9Q0F1	CCAAT/enhancer-binding protein.	Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.524
LAMA4	LAMB3	A0A2Y9LLR1	A0A2Y9PVI1	Laminin subunit alpha-4 isoform X1.	Laminin subunit beta-3.	0.704
LAMB3	LAMA4	A0A2Y9PVI1	A0A2Y9LLR1	Laminin subunit beta-3.	Laminin subunit alpha-4 isoform X1.	0.704
LOC111164929	ADRB3	A0A2Y9LUH8	A0A2Y9N6S8	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	LOW QUALITY PROTEIN: beta-3 adrenergic receptor.	0.434
LOC111164929	CEBPB	A0A2Y9LUH8	A0A2Y9Q722	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	CCAAT/enhancer-binding protein.	0.611
LOC111164929	SLC2A4	A0A2Y9LUH8	A0A2Y9Q0F1	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.576
PTGS2	CEBPB	A0A2Y9Q0P2	A0A2Y9Q722	Prostaglandin G/H synthase 2.	CCAAT/enhancer-binding protein.	0.446
SLC2A4	ADRB3	A0A2Y9Q0F1	A0A2Y9N6S8	Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	LOW QUALITY PROTEIN: beta-3 adrenergic receptor.	0.434
SLC2A4	CEBPB	A0A2Y9Q0F1	A0A2Y9Q722	Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	CCAAT/enhancer-binding protein.	0.524
SLC2A4	LOC111164929	A0A2Y9Q0F1	A0A2Y9LUH8	Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.576