STRINGSTRING
CRKL CRKL BCR BCR CCL19 CCL19 B4GALT1 B4GALT1 CNR2 CNR2 GP2 GP2 UMOD UMOD F2RL1 F2RL1 EPX EPX CCL21 CCL21 LOC111163731 LOC111163731 SELPLG SELPLG LOC111163732 LOC111163732 UMODL1 UMODL1 IL16 IL16 ITGA9 ITGA9 CCL5 CCL5 LOC111163729 LOC111163729 LOC111163733 LOC111163733 CCL22 CCL22 CX3CL1 CX3CL1 EXT1 EXT1 EMP2 EMP2 VAV1 VAV1 TNFSF14 TNFSF14 LOC111165064 LOC111165064 TBX21 TBX21 LOC111166483 LOC111166483 CCR7 CCR7 CCL17 CCL17 JAML JAML FCER1G FCER1G S100A8 S100A8 GBA GBA XCL1 XCL1 LOC111167106 LOC111167106 ITGA3 ITGA3 JAM3 JAM3 CCR6 CCR6 CXCR5 CXCR5 CRTAM CRTAM PLG PLG CD99 CD99 SLAMF1 SLAMF1 CUNH10orf99 CUNH10orf99 XG XG PODXL2 PODXL2 SELP SELP SELE SELE SLC37A4 SLC37A4 KIT KIT CX3CR1 CX3CR1 CD99L2 CD99L2 F11R F11R SLAMF8 SLAMF8 SELL SELL MSN MSN SYK SYK IL17RC IL17RC JAGN1 JAGN1 ELANE ELANE ADD2 ADD2 FUT4 FUT4 CNN2 CNN2 AIMP1 AIMP1 MMP9 MMP9 CCL20 CCL20 ITGA4 ITGA4 NKX2-3 NKX2-3 ALOX5 ALOX5 WDR1 WDR1 MADCAM1 MADCAM1 LOC111171209 LOC111171209 NCKAP1L NCKAP1L ITGB7 ITGB7 FAM19A4 FAM19A4 PIKFYVE PIKFYVE LOC111171817 LOC111171817 ANXA1 ANXA1 SCG2 SCG2 ADAM8 ADAM8 IRAK4 IRAK4 SRP54 SRP54 JAM2 JAM2 TNFSF11 TNFSF11 CH25H CH25H CXADR CXADR FLT1 FLT1 ITGA7 ITGA7 EDN2 EDN2 ITGA6 ITGA6 LGALS3 LGALS3 CHGA CHGA LOC111176429 LOC111176429 GCNT1 GCNT1 ANO6 ANO6 DOCK8 DOCK8 PTN PTN GAS6 GAS6 EDNRB EDNRB CSF3R CSF3R IL17A IL17A PTPRO PTPRO PPIB PPIB WNK1 WNK1 EPS8 EPS8 FUT7 FUT7 DBH DBH GPR15 GPR15 MCOLN2 MCOLN2 S1PR1 S1PR1 GATA3 GATA3 VAV3 VAV3 PDE4B PDE4B C5AR1 C5AR1 NEDD9 NEDD9 LOC111181112 LOC111181112 SBDS SBDS ROCK1 ROCK1 CSF1 CSF1 CCL26 CCL26 SLC12A2 SLC12A2 TRPM4 TRPM4 FOXJ1 FOXJ1 LOC111182630 LOC111182630 NUP85 NUP85 HSD3B7 HSD3B7 ITGAL ITGAL CORO1A CORO1A CCL24 CCL24 PECAM1 PECAM1 FER FER CRK CRK LBP LBP ADA ADA MYO1G MYO1G PDGFB PDGFB TRPM2 TRPM2 LOC111185731 LOC111185731 LOC111185794 LOC111185794 CXCL16 CXCL16 SPNS2 SPNS2 PAFAH1B1 PAFAH1B1 TRIM55 TRIM55 NF1 NF1 PREX1 PREX1 PPBP PPBP CXCL10 CXCL10 LOC111185888 LOC111185888 PIK3R1 PIK3R1 MSMP MSMP LOC111187580 LOC111187580 CXCL11 CXCL11 ITGA1 ITGA1 CXCL13 CXCL13 LOC111187648 LOC111187648 GOLPH3 GOLPH3 TNF TNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRKLCrk-like protein. (303 aa)
BCRBreakpoint cluster region protein isoform X1. (1275 aa)
CCL19C-C motif chemokine. (159 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (402 aa)
CNR2Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. (376 aa)
GP2Pancreatic secretory granule membrane major glycoprotein GP2. (530 aa)
UMODUromodulin. (643 aa)
F2RL1Proteinase-activated receptor 2. (315 aa)
EPXEosinophil peroxidase. (715 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
LOC111163731C-C motif chemokine. (93 aa)
SELPLGP-selectin glycoprotein ligand 1. (450 aa)
LOC111163732C-C motif chemokine. (92 aa)
UMODL1Uromodulin-like 1. (1321 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1326 aa)
ITGA9Integrin alpha-9; Belongs to the integrin alpha chain family. (1035 aa)
CCL5C-C motif chemokine. (91 aa)
LOC111163729C-C motif chemokine. (194 aa)
LOC111163733C-C motif chemokine. (90 aa)
CCL22C-C motif chemokine. (93 aa)
CX3CL1Fractalkine. (469 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
TNFSF14Tumor necrosis factor ligand superfamily member 14 isoform X1. (241 aa)
LOC111165064Plectin isoform X1. (4685 aa)
TBX21T-box transcription factor TBX21. (535 aa)
LOC111166483Signal transducer and activator of transcription. (787 aa)
CCR7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
CCL17C-C motif chemokine. (109 aa)
JAMLJunctional adhesion molecule-like. (383 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
GBAGlucosylceramidase. (585 aa)
XCL1Lymphotactin. (111 aa)
LOC111167106Protein S100-A9-like; Belongs to the S-100 family. (135 aa)
ITGA3Integrin alpha-3 isoform X1; Belongs to the integrin alpha chain family. (1068 aa)
JAM3Junctional adhesion molecule C. (301 aa)
CCR6C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
CXCR5C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (374 aa)
CRTAMCytotoxic and regulatory T-cell molecule isoform X1. (391 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (812 aa)
CD99CD99 antigen isoform X1. (200 aa)
SLAMF1Signaling lymphocytic activation molecule isoform X1. (378 aa)
CUNH10orf99Secreted protein C10orf99 homolog. (81 aa)
XGGlycoprotein Xg. (140 aa)
PODXL2Podocalyxin-like protein 2 isoform X1. (607 aa)
SELPP-selectin isoform X1. (768 aa)
SELEE-selectin. (531 aa)
SLC37A4Glucose-6-phosphate exchanger SLC37A4 isoform X1. (429 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
CX3CR1CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (475 aa)
CD99L2CD99 antigen-like protein 2 isoform X1. (300 aa)
F11RJunctional adhesion molecule A. (299 aa)
SLAMF8SLAM family member 8 isoform X1. (318 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (372 aa)
MSNMoesin isoform X1. (579 aa)
SYKTyrosine-protein kinase. (626 aa)
IL17RCInterleukin-17 receptor C isoform X1. (713 aa)
JAGN1Protein jagunal homolog 1. (183 aa)
ELANENeutrophil elastase; Belongs to the peptidase S1 family. (308 aa)
ADD2Beta-adducin isoform X1. (836 aa)
FUT4Alpha-(1,3)-fucosyltransferase 4. (458 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (380 aa)
AIMP1Aminoacyl tRNA synthase complex-interacting multifunctional protein 1. (321 aa)
MMP9Matrix metalloproteinase-9. (709 aa)
CCL20C-C motif chemokine. (97 aa)
ITGA4Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa)
NKX2-3Homeobox protein Nkx-2.3. (366 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
WDR1WD repeat-containing protein 1. (606 aa)
MADCAM1Mucosal addressin cell adhesion molecule 1. (406 aa)
LOC111171209C-C motif chemokine 13-like. (116 aa)
NCKAP1LNck-associated protein 1-like isoform X1. (1156 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (819 aa)
FAM19A4Protein FAM19A4. (145 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform X1. (2110 aa)
LOC111171817C-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family. (368 aa)
ANXA1Annexin. (346 aa)
SCG2Secretogranin-2. (615 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa)
IRAK4Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
JAM2Junctional adhesion molecule B isoform X1. (350 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
CH25HCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (270 aa)
CXADRCoxsackievirus and adenovirus receptor isoform X1. (365 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
ITGA7Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1141 aa)
EDN2Endothelin-2. (147 aa)
ITGA6Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1091 aa)
LGALS3Galectin. (256 aa)
CHGAchromogranin-A isoform X1. (445 aa)
LOC111176429G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (360 aa)
GCNT1beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase isoform X1. (485 aa)
ANO6Anoctamin. (951 aa)
DOCK8Dedicator of cytokinesis protein 8 isoform X1; Belongs to the DOCK family. (2098 aa)
PTNPleiotrophin isoform X1. (168 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa)
CSF3RGranulocyte colony-stimulating factor receptor isoform X1. (846 aa)
IL17Ainterleukin-17A. (155 aa)
PTPROReceptor-type tyrosine-protein phosphatase O isoform X1. (1216 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
WNK1Serine/threonine-protein kinase WNK1 isoform X1. (2825 aa)
EPS8Epidermal growth factor receptor kinase substrate 8. (818 aa)
FUT7Alpha-(1,3)-fucosyltransferase 7. (342 aa)
DBHDopamine beta-hydroxylase. (610 aa)
GPR15G-protein coupled receptor 15; Belongs to the G-protein coupled receptor 1 family. (358 aa)
MCOLN2Mucolipin-2 isoform X1. (566 aa)
S1PR1Sphingosine 1-phosphate receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (455 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
VAV3Guanine nucleotide exchange factor VAV3. (954 aa)
PDE4BPhosphodiesterase. (736 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (424 aa)
NEDD9Enhancer of filamentation 1 isoform X1. (829 aa)
LOC111181112Uncharacterized protein LOC111181112. (257 aa)
SBDSRibosome maturation protein SBDS. (250 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
CCL26C-C motif chemokine 26. (94 aa)
SLC12A2Solute carrier family 12 member 2 isoform X1. (1203 aa)
TRPM4LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 4. (1204 aa)
FOXJ1Forkhead box protein J1. (422 aa)
LOC111182630Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
HSD3B73 beta-hydroxysteroid dehydrogenase type 7 isoform X1. (414 aa)
ITGALIntegrin alpha-L; Belongs to the integrin alpha chain family. (1166 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CCL24C-C motif chemokine 24. (119 aa)
PECAM1Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
LBPLipopolysaccharide-binding protein isoform X1. (537 aa)
ADAAdenosine deaminase isoform X1. (416 aa)
MYO1GUnconventional myosin-Ig isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (278 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1497 aa)
LOC111185731C-C motif chemokine. (99 aa)
LOC111185794C-C motif chemokine. (97 aa)
CXCL16C-X-C motif chemokine 16 isoform X1. (316 aa)
SPNS2Protein spinster homolog 2 isoform X4. (549 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
TRIM55Tripartite motif-containing protein 55 isoform X1. (534 aa)
NF1Neurofibromin isoform X1. (2873 aa)
PREX1Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein isoform X1. (1653 aa)
PPBPC-X-C motif chemokine. (119 aa)
CXCL10C-X-C motif chemokine. (103 aa)
LOC111185888C-C motif chemokine. (99 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
MSMPBeta-microseminoprotein. (139 aa)
LOC111187580C-X-C motif chemokine. (112 aa)
CXCL11C-X-C motif chemokine 11. (100 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
CXCL13C-X-C motif chemokine 13. (109 aa)
LOC111187648C-X-C motif chemokine 6-like. (113 aa)
GOLPH3Golgi phosphoprotein 3. (298 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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