STRINGSTRING
TGM2 TGM2 ARRB1 ARRB1 IGF1 IGF1 F2R F2R F2RL1 F2RL1 RTN4R RTN4R RELN RELN ADGRG1 ADGRG1 FGF10 FGF10 PIK3CG PIK3CG RASGEF1A RASGEF1A F2RL3 F2RL3 APOA1 APOA1 NTRK1 NTRK1 CDON CDON LRRC59 LRRC59 P2RY8 P2RY8 AKAP13 AKAP13 F11R F11R MMD2 MMD2 GPR55 GPR55 ITGAV ITGAV COL3A1 COL3A1 STK19 STK19 NET1 NET1 GPR35 GPR35 SHOC2 SHOC2 ARHGEF3 ARHGEF3 LPAR6 LPAR6 MCF2L MCF2L KRAS KRAS GPR65 GPR65 ITPKB ITPKB GPR18 GPR18 LOC111178270 LOC111178270 LOC111178272 LOC111178272 LPAR1 LPAR1 NOTCH1 NOTCH1 ROBO1 ROBO1 PIK3CB PIK3CB ABRA ABRA GPR174 GPR174 DGKI DGKI LPAR4 LPAR4 LRRC7 LRRC7 LRRD1 LRRD1 MAPRE2 MAPRE2 NOTCH2 NOTCH2 CSF1 CSF1 AUTS2 AUTS2 RASGRP1 RASGRP1 RASGRP4 RASGRP4 GPR17 GPR17 EPO EPO SRC SRC SYNPO2L SYNPO2L F2RL2 F2RL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGM2Protein-glutamine gamma-glutamyltransferase 2. (687 aa)
ARRB1Beta-arrestin-1 isoform X1. (430 aa)
IGF1Insulin-like growth factor I isoform X1. (186 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
F2RL1Proteinase-activated receptor 2. (315 aa)
RTN4RReticulon-4 receptor. (481 aa)
RELNReelin isoform X1. (3460 aa)
ADGRG1Adhesion G-protein coupled receptor G1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (686 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa)
RASGEF1Aras-GEF domain-containing family member 1A isoform X2. (488 aa)
F2RL3Proteinase-activated receptor 4; Belongs to the G-protein coupled receptor 1 family. (380 aa)
APOA1Apolipoprotein A-I. (265 aa)
NTRK1Tyrosine-protein kinase receptor. (795 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes isoform X1. (1279 aa)
LRRC59Leucine-rich repeat-containing protein 59 isoform X1. (334 aa)
P2RY8P2Y purinoceptor 8; Belongs to the G-protein coupled receptor 1 family. (353 aa)
AKAP13A-kinase anchor protein 13 isoform X5. (1430 aa)
F11RJunctional adhesion molecule A. (299 aa)
MMD2Monocyte to macrophage differentiation factor 2 isoform X1. (278 aa)
GPR55G-protein coupled receptor 55 isoform X1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
ITGAVIntegrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
COL3A1Collagen alpha-1(III) chain. (1464 aa)
STK19Serine/threonine-protein kinase 19 isoform X1. (254 aa)
NET1Neuroepithelial cell-transforming gene 1 protein isoform X1. (596 aa)
GPR35G-protein coupled receptor 35; Belongs to the G-protein coupled receptor 1 family. (305 aa)
SHOC2Leucine-rich repeat protein SHOC-2 isoform X1. (582 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3 isoform X1. (558 aa)
LPAR6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (344 aa)
MCF2LGuanine nucleotide exchange factor DBS isoform X1. (1240 aa)
KRASGTPase KRas. (188 aa)
GPR65Psychosine receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa)
GPR18N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. (338 aa)
LOC111178270Putative P2Y purinoceptor 10 isoform X1. (359 aa)
LOC111178272Putative P2Y purinoceptor 10 isoform X2. (379 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
ROBO1Roundabout homolog 1 isoform X1. (1685 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
ABRAActin-binding Rho-activating protein. (398 aa)
GPR174Probable G-protein coupled receptor 174. (333 aa)
DGKIDiacylglycerol kinase. (1079 aa)
LPAR4Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa)
LRRC7Leucine-rich repeat-containing protein 7 isoform X8. (1575 aa)
LRRD1Leucine-rich repeat and death domain-containing protein 1. (869 aa)
MAPRE2Microtubule-associated protein RP/EB family member 2 isoform X1. (326 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
AUTS2Autism susceptibility gene 2 protein. (1264 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (870 aa)
RASGRP4RAS guanyl-releasing protein 4 isoform X1. (669 aa)
GPR17Uracil nucleotide/cysteinyl leukotriene receptor; Belongs to the G-protein coupled receptor 1 family. (339 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
SRCTyrosine-protein kinase. (562 aa)
SYNPO2LLOW QUALITY PROTEIN: synaptopodin 2-like protein. (978 aa)
F2RL2Proteinase-activated receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (438 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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