STRINGSTRING
YWHAE YWHAE CRKL CRKL LDLRAP1 LDLRAP1 FGR FGR MAPK1 MAPK1 SFN SFN BCAR3 BCAR3 EPB41 EPB41 UBASH3A UBASH3A PHF6 PHF6 VAV1 VAV1 SH3BP2 SH3BP2 PIN1 PIN1 MID2 MID2 SHD SHD PIK3R2 PIK3R2 ABL2 ABL2 SHC1 SHC1 FBXW9 FBXW9 TOX3 TOX3 MID1 MID1 UBASH3B UBASH3B CBL CBL ARR3 ARR3 SHC3 SHC3 LOC111167689 LOC111167689 SH2D3A SH2D3A SHE SHE SCAF8 SCAF8 LRP11 LRP11 GPRIN1 GPRIN1 PCIF1 PCIF1 IGF2R IGF2R SYK SYK IRS1 IRS1 SCAF4 SCAF4 BTRC BTRC PLAT PLAT SAG SAG PIK3R3 PIK3R3 TBK1 TBK1 VAV2 VAV2 THRAP3 THRAP3 SAMSN1 SAMSN1 PTPN3 PTPN3 LEO1 LEO1 PTPN6 PTPN6 LCK LCK SH2D3C SH2D3C PKD2 PKD2 LOC111177621 LOC111177621 ABL1 ABL1 PLCG2 PLCG2 DPYS DPYS PTPN5 PTPN5 RTF1 RTF1 YES1 YES1 MAPK3 MAPK3 PIH1D1 PIH1D1 URI1 URI1 SHF SHF SOCS3 SOCS3 GRB2 GRB2 TBL2 TBL2 LOC111184310 LOC111184310 BBS1 BBS1 CBX4 CBX4 MEN1 MEN1 RASA1 RASA1 SRC SRC HCK HCK CRK CRK YWHAB YWHAB CBLB CBLB LOC111186271 LOC111186271 TRPV1 TRPV1 PAFAH1B1 PAFAH1B1 LOC111186270 LOC111186270 LOC111187417 LOC111187417 PIK3R1 PIK3R1 MTOR MTOR NCK2 NCK2 FBXW7 FBXW7 PTPN11 PTPN11 LOC111187198 LOC111187198 SHB SHB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YWHAE14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
CRKLCrk-like protein. (303 aa)
LDLRAP1LOW QUALITY PROTEIN: low density lipoprotein receptor adapter protein 1. (309 aa)
FGRTyrosine-protein kinase. (526 aa)
MAPK1Mitogen-activated protein kinase. (380 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
BCAR3Breast cancer anti-estrogen resistance protein 3 isoform X1. (832 aa)
EPB41Protein 4.1 isoform X2. (891 aa)
UBASH3AUbiquitin-associated and SH3 domain-containing protein A isoform X1. (623 aa)
PHF6PHD finger protein 6 isoform X1. (366 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
SH3BP2SH3 domain-binding protein 2 isoform X1. (617 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
MID2Probable E3 ubiquitin-protein ligase MID2 isoform X4. (770 aa)
SHDSH2 domain-containing adapter protein D. (340 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
ABL2Tyrosine-protein kinase. (1174 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
FBXW9F-box/WD repeat-containing protein 9 isoform X1. (461 aa)
TOX3TOX high mobility group box family member 3 isoform X1. (570 aa)
MID1E3 ubiquitin-protein ligase Midline-1 isoform X1. (667 aa)
UBASH3BUbiquitin-associated and SH3 domain-containing protein B isoform X1. (649 aa)
CBLE3 ubiquitin-protein ligase CBL isoform X1. (910 aa)
ARR3arrestin-C. (339 aa)
SHC3SHC-transforming protein 3. (588 aa)
LOC111167689GRB2-related adapter protein. (217 aa)
SH2D3ASH2 domain-containing protein 3A isoform X1. (601 aa)
SHESH2 domain-containing adapter protein E. (499 aa)
SCAF8Protein SCAF8 isoform X5. (1348 aa)
LRP11Low-density lipoprotein receptor-related protein 11 isoform X1. (505 aa)
GPRIN1LOW QUALITY PROTEIN: G protein-regulated inducer of neurite outgrowth 1. (935 aa)
PCIF1Phosphorylated CTD-interacting factor 1 isoform X1. (732 aa)
IGF2RCation-independent mannose-6-phosphate receptor. (2490 aa)
SYKTyrosine-protein kinase. (626 aa)
IRS1Insulin receptor substrate 1. (1248 aa)
SCAF4Splicing factor, arginine/serine-rich 15 isoform X1. (1133 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (607 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (565 aa)
SAGS-arrestin. (408 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
THRAP3Thyroid hormone receptor-associated protein 3. (958 aa)
SAMSN1SAM domain-containing protein SAMSN-1. (373 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (949 aa)
LEO1RNA polymerase-associated protein LEO1 isoform X1. (672 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
LCKTyrosine-protein kinase. (509 aa)
SH2D3CSH2 domain-containing protein 3C isoform X1. (861 aa)
PKD2Polycystin-2 isoform X1. (975 aa)
LOC111177621RNA polymerase-associated protein LEO1-like. (292 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
DPYSDihydropyrimidinase isoform X1. (553 aa)
PTPN5Tyrosine-protein phosphatase non-receptor type 5. (539 aa)
RTF1RNA polymerase-associated protein RTF1 homolog. (710 aa)
YES1Tyrosine-protein kinase. (541 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
PIH1D1PIH1 domain-containing protein 1. (290 aa)
URI1Unconventional prefoldin RPB5 interactor 1. (529 aa)
SHFLOW QUALITY PROTEIN: SH2 domain-containing adapter protein F. (489 aa)
SOCS3Suppressor of cytokine signaling 3. (237 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
TBL2Transducin beta-like protein 2. (446 aa)
LOC111184310Tyrosine-protein kinase. (369 aa)
BBS1Bardet-Biedl syndrome 1 protein. (593 aa)
CBX4E3 SUMO-protein ligase CBX4. (550 aa)
MEN1Menin isoform X1. (616 aa)
RASA1Ras GTPase-activating protein 1 isoform X1. (1040 aa)
SRCTyrosine-protein kinase. (562 aa)
HCKTyrosine-protein kinase. (506 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
YWHAB14-3-3 protein beta/alpha isoform X1; Belongs to the 14-3-3 family. (246 aa)
CBLBE3 ubiquitin-protein ligase CBL-B. (983 aa)
LOC111186271GRB2-related adapter protein 2-like isoform X1. (105 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (864 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
LOC111186270GRB2-related adapter protein 2 isoform X1. (337 aa)
LOC111187417Tyrosine-protein kinase. (612 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
NCK2Cytoplasmic protein. (376 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform X1. (707 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LOC111187198Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
SHBSH2 domain-containing adapter protein B. (507 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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