STRINGSTRING
MTOR MTOR PHLDB2 PHLDB2 PIK3R1 PIK3R1 ARHGEF15 ARHGEF15 ARAP1 ARAP1 SERPINF2 SERPINF2 INPP5K INPP5K PAK1 PAK1 SYNPO2L SYNPO2L SYNPO SYNPO WNT11 WNT11 PPFIA1 PPFIA1 ACTG1 ACTG1 LIMK1 LIMK1 RHPN2 RHPN2 FHOD1 FHOD1 PFN2 PFN2 RHOC RHOC CGNL1 CGNL1 TGFB3 TGFB3 NRP1 NRP1 EPHA1 EPHA1 MET MET ABL1 ABL1 ASAP3 ASAP3 PPM1E PPM1E NF2 NF2 PPM1F PPM1F ARHGAP28 ARHGAP28 ITGB1BP1 ITGB1BP1 RHPN1 RHPN1 WASF2 WASF2 CTGF CTGF ARHGEF18 ARHGEF18 PIK3R2 PIK3R2 APOA1 APOA1 MYOC MYOC ARHGAP6 ARHGAP6 ALMS1 ALMS1 CARMIL1 CARMIL1 WAS WAS F11R F11R S100A10 S100A10 SORBS3 SORBS3 LIMCH1 LIMCH1 TMEFF2 TMEFF2 PAK2 PAK2 SFRP1 SFRP1 RAPGEF3 RAPGEF3 DLC1 DLC1 FERMT2 FERMT2 ARHGEF10 ARHGEF10 TTC8 TTC8 RHOA RHOA EVL EVL GPR65 GPR65 TSC1 TSC1 TACSTD2 TACSTD2 LPAR1 LPAR1 BRAF BRAF CORO2B CORO2B BBS4 BBS4 PTGER4 PTGER4 TGFBR1 TGFBR1 CORO2A CORO2A TESK1 TESK1 CCDC88A CCDC88A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
PHLDB2Pleckstrin homology-like domain family B member 2 isoform X1. (1364 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (844 aa)
ARAP1arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1. (1455 aa)
SERPINF2Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (558 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform X1. (476 aa)
PAK1Non-specific serine/threonine protein kinase. (543 aa)
SYNPO2LLOW QUALITY PROTEIN: synaptopodin 2-like protein. (978 aa)
SYNPOSynaptopodin isoform X1. (901 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PPFIA1Liprin-alpha-1 isoform X4. (1242 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
LIMK1LIM domain kinase 1 isoform X1. (647 aa)
RHPN2Rhophilin-2. (688 aa)
FHOD1FH1/FH2 domain-containing protein 1 isoform X1. (1195 aa)
PFN2Profilin; Belongs to the profilin family. (197 aa)
RHOCRho-related GTP-binding protein RhoC isoform X1. (242 aa)
CGNL1Cingulin-like protein 1. (1299 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
EPHA1Ephrin type-A receptor 1 isoform X1. (981 aa)
METHepatocyte growth factor receptor isoform X1. (1382 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
ASAP3arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X1. (906 aa)
PPM1EProtein phosphatase 1E. (749 aa)
NF2Merlin isoform X3. (619 aa)
PPM1FProtein phosphatase 1F. (433 aa)
ARHGAP28Rho GTPase-activating protein 28 isoform X1. (778 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (206 aa)
RHPN1Rhophilin-1 isoform X1. (660 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (498 aa)
CTGFConnective tissue growth factor isoform X1. (349 aa)
ARHGEF18Rho guanine nucleotide exchange factor 18 isoform X1. (1420 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
APOA1Apolipoprotein A-I. (265 aa)
MYOCMyocilin. (476 aa)
ARHGAP6Rho GTPase-activating protein 6 isoform X1. (977 aa)
ALMS1Alstrom syndrome protein 1 isoform X1. (4198 aa)
CARMIL1F-actin-uncapping protein LRRC16A isoform X1. (1453 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
F11RJunctional adhesion molecule A. (299 aa)
S100A10Protein S100-A10; Belongs to the S-100 family. (96 aa)
SORBS3Vinexin isoform X3. (677 aa)
LIMCH1LIM and calponin homology domains-containing protein 1 isoform X7. (1629 aa)
TMEFF2Tomoregulin-2. (374 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
SFRP1Secreted frizzled-related protein 1. (308 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3 isoform X2. (958 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
FERMT2Fermitin family homolog 2 isoform X2. (691 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10 isoform X1. (1405 aa)
TTC8Tetratricopeptide repeat protein 8 isoform X1. (515 aa)
RHOATransforming protein RhoA. (193 aa)
EVLena/VASP-like protein isoform X1. (436 aa)
GPR65Psychosine receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
TSC1Hamartin. (1169 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (323 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X1. (762 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (475 aa)
BBS4Bardet-Biedl syndrome 4 protein isoform X1. (528 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (486 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (525 aa)
TESK1Dual specificity testis-specific protein kinase 1 isoform X1. (628 aa)
CCDC88AGirdin isoform X1. (2055 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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