STRINGSTRING
PNPLA6 PNPLA6 ABHD5 ABHD5 CA2 CA2 PNPLA4 PNPLA4 PAFAH1B2 PAFAH1B2 ENPP2 ENPP2 SIAE SIAE ACOT9 ACOT9 ABHD8 ABHD8 PGLS PGLS LPL LPL MGLL MGLL ABHD2 ABHD2 TARS2 TARS2 PNPLA2 PNPLA2 IARS IARS VARS VARS VARS2 VARS2 LOC111171190 LOC111171190 TMEM8B TMEM8B ABHD10 ABHD10 H6PD H6PD PNLIPRP2 PNLIPRP2 TNFAIP6 TNFAIP6 PNLIPRP1 PNLIPRP1 LOC111173012 LOC111173012 PRDX6 PRDX6 PLA2G12A PLA2G12A LIPA LIPA LIPH LIPH LOC111172609 LOC111172609 ABHD16A ABHD16A DDHD2 DDHD2 PGAP1 PGAP1 HRASLS HRASLS LOC111172637 LOC111172637 NCEH1 NCEH1 PLB1 PLB1 ABHD6 ABHD6 ACOT11 ACOT11 LARS2 LARS2 BCHE BCHE LOC111175416 LOC111175416 PLA1A PLA1A TM7SF3 TM7SF3 CEL CEL ESD ESD FAAH FAAH PLA2G7 PLA2G7 FAM78A FAM78A IARS2 IARS2 RPE65 RPE65 LCAT LCAT DPH7 DPH7 PTRH1 PTRH1 AARS AARS LYPLAL1 LYPLAL1 LIPG LIPG LIPC LIPC AARS2 AARS2 PAFAH1B3 PAFAH1B3 PON2 PON2 AOAH AOAH LIPE LIPE PLA2G4F PLA2G4F PLA2G15 PLA2G15 CES2 CES2 PON1 PON1 PLA2G4E PLA2G4E ABHD11 ABHD11 ACHE ACHE GDPD3 GDPD3 ABHD3 ABHD3 PON3 PON3 MRPL58 MRPL58 BPHL BPHL LARS LARS DAGLB DAGLB PLA2G12B PLA2G12B NOTUM NOTUM NDST1 NDST1 DTD1 DTD1 TMEM8A TMEM8A NDST2 NDST2 CHKA CHKA LOC111183835 LOC111183835 DAGLA DAGLA HRASLS5 HRASLS5 ABHD12 ABHD12 APMAP APMAP PNPLA8 PNPLA8 PLA2G4A PLA2G4A ACOT12 ACOT12 ABHD16B ABHD16B PPME1 PPME1 LOC111184999 LOC111184999 NDST3 NDST3 ABHD15 ABHD15 PROCA1 PROCA1 ACOT7 ACOT7 PLA2G6 PLA2G6 SDAD1 SDAD1 PNPLA3 PNPLA3 LOC111186556 LOC111186556 ALDH2 ALDH2 PLA2G3 PLA2G3 PLA2G2F PLA2G2F PAFAH2 PAFAH2 PLA2G5 PLA2G5 PLA2G10 PLA2G10 GDPD1 GDPD1 PTRH2 PTRH2 ABHD4 ABHD4 DTD2 DTD2 PLA2G2D PLA2G2D GDE1 GDE1 PLA2G1B PLA2G1B LYPLA2 LYPLA2 PLA2G2C PLA2G2C LOC111163294 LOC111163294 RGN RGN LYPLA1 LYPLA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PNPLA6Neuropathy target esterase isoform X1. (1388 aa)
ABHD51-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform X1. (389 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
PNPLA4Patatin-like phospholipase domain-containing protein 4 isoform X1. (256 aa)
PAFAH1B2Platelet-activating factor acetylhydrolase IB subunit beta. (229 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X1. (955 aa)
SIAESialate O-acetylesterase isoform X1. (521 aa)
ACOT9Acyl-coenzyme A thioesterase 9, mitochondrial isoform X1. (457 aa)
ABHD8Protein ABHD8. (432 aa)
PGLS6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (258 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (478 aa)
MGLLMonoglyceride lipase isoform X1. (313 aa)
ABHD2Monoacylglycerol lipase ABHD2 isoform X1. (425 aa)
TARS2threonine--tRNA ligase, mitochondrial isoform X1. (718 aa)
PNPLA2Patatin-like phospholipase domain-containing protein 2 isoform X1. (489 aa)
IARSisoleucine--tRNA ligase, cytoplasmic isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family. (1274 aa)
VARSvaline--tRNA ligase isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family. (1265 aa)
VARS2valine--tRNA ligase, mitochondrial isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family. (1061 aa)
LOC111171190Phospholipase A1 member A-like. (183 aa)
TMEM8BTransmembrane protein 8B isoform X1. (1028 aa)
ABHD10Mycophenolic acid acyl-glucuronide esterase, mitochondrial. (303 aa)
H6PDGDH/6PGL endoplasmic bifunctional protein isoform X1. (822 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
TNFAIP6Tumor necrosis factor-inducible gene 6 protein isoform X1. (284 aa)
PNLIPRP1Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (467 aa)
LOC111173012Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial. (134 aa)
PRDX6Peroxiredoxin-6. (224 aa)
PLA2G12AGroup XIIA secretory phospholipase A2. (189 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
LIPHLipase member H isoform X1. (451 aa)
LOC111172609Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
ABHD16AProtein ABHD16A isoform X1. (558 aa)
DDHD2Phospholipase DDHD2 isoform X1. (1079 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
HRASLSPhospholipid-metabolizing enzyme A-C1 isoform X1. (249 aa)
LOC111172637Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (397 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (408 aa)
PLB1Phospholipase B1, membrane-associated isoform X1. (1463 aa)
ABHD6Monoacylglycerol lipase ABHD6. (337 aa)
ACOT11Acyl-coenzyme A thioesterase 11 isoform X1. (593 aa)
LARS2Probable leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (903 aa)
BCHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (643 aa)
LOC111175416Fatty-acid amide hydrolase 1-like. (94 aa)
PLA1APhospholipase A1 member A. (315 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (621 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (311 aa)
FAAHFatty-acid amide hydrolase 1 isoform X1. (655 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (443 aa)
FAM78AProtein FAM78A. (283 aa)
IARS2isoleucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1012 aa)
RPE65Retinoid isomerohydrolase. (533 aa)
LCATPhosphatidylcholine-sterol acyltransferase isoform X1. (440 aa)
DPH7Diphthine methyltransferase isoform X1. (409 aa)
PTRH1Probable peptidyl-tRNA hydrolase. (203 aa)
AARSalanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
LYPLAL1Lysophospholipase-like protein 1. (232 aa)
LIPGEndothelial lipase. (505 aa)
LIPCHepatic triacylglycerol lipase isoform X1. (510 aa)
AARS2alanine--tRNA ligase, mitochondrial; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (985 aa)
PAFAH1B3Platelet-activating factor acetylhydrolase IB subunit gamma. (232 aa)
PON2Serum paraoxonase/arylesterase 2 isoform X1. (354 aa)
AOAHAcyloxyacyl hydrolase isoform X1. (671 aa)
LIPEHormone-sensitive lipase isoform X1. (799 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLA2G15Group XV phospholipase A2 isoform X1. (446 aa)
CES2Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (572 aa)
PON1LOW QUALITY PROTEIN: serum paraoxonase/arylesterase 1. (360 aa)
PLA2G4EPhospholipase A2. (868 aa)
ABHD11Protein ABHD11 isoform X1. (232 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (617 aa)
GDPD3Glycerophosphodiester phosphodiesterase domain-containing protein 3. (318 aa)
ABHD3Phospholipase ABHD3 isoform X1. (411 aa)
PON3Serum paraoxonase/lactonase 3 isoform X1. (354 aa)
MRPL58peptidyl-tRNA hydrolase ICT1, mitochondrial. (206 aa)
BPHLValacyclovir hydrolase isoform X1. (297 aa)
LARSleucine--tRNA ligase, cytoplasmic isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family. (1175 aa)
DAGLBSn1-specific diacylglycerol lipase beta isoform X1. (669 aa)
PLA2G12BGroup XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
NOTUMPalmitoleoyl-protein carboxylesterase NOTUM. (499 aa)
NDST1Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 isoform X1. (882 aa)
DTD1D-aminoacyl-tRNA deacylase. (209 aa)
TMEM8ATransmembrane protein 8A isoform X1. (793 aa)
NDST2Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2. (883 aa)
CHKACholine kinase alpha isoform X2. (611 aa)
LOC111183835HRAS-like suppressor 3. (162 aa)
DAGLASn1-specific diacylglycerol lipase alpha isoform X1. (1040 aa)
HRASLS5LOW QUALITY PROTEIN: Ca(2+)-independent N-acyltransferase. (303 aa)
ABHD12Monoacylglycerol lipase ABHD12 isoform X1. (507 aa)
APMAPAdipocyte plasma membrane-associated protein. (415 aa)
PNPLA8Calcium-independent phospholipase A2-gamma isoform X1. (784 aa)
PLA2G4APhospholipase A2. (749 aa)
ACOT12Acyl-coenzyme A thioesterase 12. (557 aa)
ABHD16BLOW QUALITY PROTEIN: protein ABHD16B. (471 aa)
PPME1Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. (386 aa)
LOC111184999Small integral membrane protein 26-like. (94 aa)
NDST3Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 isoform X1. (887 aa)
ABHD15Protein ABHD15. (468 aa)
PROCA1Protein PROCA1 isoform X1. (376 aa)
ACOT7Cytosolic acyl coenzyme A thioester hydrolase isoform X1. (375 aa)
PLA2G685/88 kDa calcium-independent phospholipase A2 isoform X2. (835 aa)
SDAD1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (688 aa)
PNPLA3Patatin-like phospholipase domain-containing protein 3 isoform X1. (415 aa)
LOC111186556prolyl-tRNA synthetase associated domain-containing protein 1. (171 aa)
ALDH2Aldehyde dehydrogenase, mitochondrial isoform X1; Belongs to the aldehyde dehydrogenase family. (519 aa)
PLA2G3Group 3 secretory phospholipase A2 isoform X1. (516 aa)
PLA2G2FPhospholipase A(2). (300 aa)
PAFAH2Platelet-activating factor acetylhydrolase. (392 aa)
PLA2G5Phospholipase A(2). (156 aa)
PLA2G10Phospholipase A(2). (159 aa)
GDPD1Glycerophosphodiester phosphodiesterase domain-containing protein 1 isoform X1. (319 aa)
PTRH2peptidyl-tRNA hydrolase 2, mitochondrial. (179 aa)
ABHD4Protein ABHD4 isoform X1. (355 aa)
DTD2Probable D-tyrosyl-tRNA(Tyr) deacylase 2 isoform X1. (168 aa)
PLA2G2DPhospholipase A(2). (161 aa)
GDE1Glycerophosphodiester phosphodiesterase 1 isoform X1. (366 aa)
PLA2G1BPhospholipase A(2). (160 aa)
LYPLA2Acyl-protein thioesterase 2. (231 aa)
PLA2G2CPutative inactive group IIC secretory phospholipase A2. (107 aa)
LOC111163294Phospholipase A(2). (116 aa)
RGNRegucalcin. (301 aa)
LYPLA1Acyl-protein thioesterase 1. (230 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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