(17 nodes) Pericardium development network (Delphinapterus leucas)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TBX5	T-box transcription factor TBX5 isoform X1. (519 aa)
	RPGRIP1L	Protein fantom. (1269 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	HEG1	Protein HEG homolog 1 isoform X1. (1474 aa)
	SETD2	Histone-lysine N-methyltransferase SETD2 isoform X1. (2570 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	NOTCH1	Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	TBX20	T-box transcription factor TBX20. (449 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	WT1	Wilms tumor protein isoform X1. (450 aa)
	CCM2	Cerebral cavernous malformations 2 protein isoform X1. (511 aa)
	FLRT3	Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
	NKX2-6	Homeobox protein Nkx-2.6. (300 aa)
	HAND2	LOW QUALITY PROTEIN: heart- and neural crest derivatives-expressed protein 2. (217 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	BMP7	A0A2Y9LYV6	A0A2Y9QCJ3	Bone morphogenetic protein 2.	Bone morphogenetic protein 7.	0.661
BMP2	SMAD3	A0A2Y9LYV6	A0A2Y9NWL7	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.591
BMP7	BMP2	A0A2Y9QCJ3	A0A2Y9LYV6	Bone morphogenetic protein 7.	Bone morphogenetic protein 2.	0.661
BMP7	SMAD3	A0A2Y9QCJ3	A0A2Y9NWL7	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.591
CCM2	SETD2	A0A2Y9PTG5	A0A2Y9N461	Cerebral cavernous malformations 2 protein isoform X1.	Histone-lysine N-methyltransferase SETD2 isoform X1.	0.402
DLL4	NOTCH1	A0A2Y9P7X1	A0A2Y9NWE7	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch homolog protein 1 isoform X1.	0.998
HAND2	TBX20	A0A2Y9PZH1	A0A2Y9P1V7	LOW QUALITY PROTEIN: heart- and neural crest derivatives-expressed protein 2.	T-box transcription factor TBX20.	0.555
HAND2	TBX5	A0A2Y9PZH1	A0A2Y9LAN0	LOW QUALITY PROTEIN: heart- and neural crest derivatives-expressed protein 2.	T-box transcription factor TBX5 isoform X1.	0.744
HEG1	NOTCH1	A0A2Y9MQX5	A0A2Y9NWE7	Protein HEG homolog 1 isoform X1.	Neurogenic locus notch homolog protein 1 isoform X1.	0.457
NOTCH1	DLL4	A0A2Y9NWE7	A0A2Y9P7X1	Neurogenic locus notch homolog protein 1 isoform X1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.998
NOTCH1	HEG1	A0A2Y9NWE7	A0A2Y9MQX5	Neurogenic locus notch homolog protein 1 isoform X1.	Protein HEG homolog 1 isoform X1.	0.457
SETD2	CCM2	A0A2Y9N461	A0A2Y9PTG5	Histone-lysine N-methyltransferase SETD2 isoform X1.	Cerebral cavernous malformations 2 protein isoform X1.	0.402
SMAD3	BMP2	A0A2Y9NWL7	A0A2Y9LYV6	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 2.	0.591
SMAD3	BMP7	A0A2Y9NWL7	A0A2Y9QCJ3	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 7.	0.591
TBX20	HAND2	A0A2Y9P1V7	A0A2Y9PZH1	T-box transcription factor TBX20.	LOW QUALITY PROTEIN: heart- and neural crest derivatives-expressed protein 2.	0.555
TBX5	HAND2	A0A2Y9LAN0	A0A2Y9PZH1	T-box transcription factor TBX5 isoform X1.	LOW QUALITY PROTEIN: heart- and neural crest derivatives-expressed protein 2.	0.744