STRINGSTRING
ZFPM2 ZFPM2 TGFBR1 TGFBR1 MAPK11 MAPK11 TP73 TP73 MEF2C MEF2C GATA6 GATA6 JARID2 JARID2 WNT2 WNT2 TBX20 TBX20 NOTCH1 NOTCH1 PIM1 PIM1 GLI1 GLI1 FGF20 FGF20 FGF9 FGF9 SAV1 SAV1 ERBB4 ERBB4 YAP1 YAP1 BMP10 BMP10 BMPR1A BMPR1A HEY2 HEY2 TBX2 TBX2 NOG NOG TBX5 TBX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZFPM2Zinc finger protein ZFPM2. (1151 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (637 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X6. (483 aa)
GATA6Transcription factor GATA-6. (592 aa)
JARID2Protein Jumonji isoform X1. (1235 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
TBX20T-box transcription factor TBX20. (449 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (347 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SAV1Protein salvador homolog 1. (385 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
YAP1Transcriptional coactivator YAP1 isoform X1. (511 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
TBX2T-box transcription factor TBX2. (713 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TBX5T-box transcription factor TBX5 isoform X1. (519 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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