STRINGSTRING
PROX1 PROX1 SLIT3 SLIT3 ZFPM1 ZFPM1 HEYL HEYL WNT5A WNT5A HES1 HES1 SAV1 SAV1 BMP4 BMP4 FZD2 FZD2 BMPR2 BMPR2 CITED2 CITED2 BMPR1A BMPR1A NSD2 NSD2 HEY2 HEY2 EGLN1 EGLN1 NOG NOG TBX3 TBX3 APLNR APLNR NOTCH1 NOTCH1 NKX2-5 NKX2-5 RBM15 RBM15 SMAD4 SMAD4 ZFPM2 ZFPM2 SMAD7 SMAD7 WNT11 WNT11 TGFBR1 TGFBR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PROX1Prospero homeobox protein 1 isoform X1. (738 aa)
SLIT3Slit homolog 3 protein isoform X2. (1523 aa)
ZFPM1Zinc finger protein ZFPM1 isoform X1. (1069 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (357 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
HES1Transcription factor HES-1. (280 aa)
SAV1Protein salvador homolog 1. (385 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (408 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
CITED2Cbp/p300-interacting transactivator 2. (272 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NSD2Histone-lysine N-methyltransferase NSD2 isoform X1. (1375 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
EGLN1Egl nine homolog 1. (439 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TBX3T-box transcription factor TBX3 isoform X1. (745 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
RBM15Putative RNA-binding protein 15. (962 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
ZFPM2Zinc finger protein ZFPM2. (1151 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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