STRINGSTRING
PRKCD PRKCD CDC42EP3 CDC42EP3 PLEK2 PLEK2 PLCE1 PLCE1 VDAC3 VDAC3 IFT88 IFT88 CENPJ CENPJ RHOQ RHOQ TWF1 TWF1 SAXO1 SAXO1 ZMYND10 ZMYND10 PLD1 PLD1 NCKAP1 NCKAP1 GPM6A GPM6A PIK3CA PIK3CA TBC1D30 TBC1D30 RCC2 RCC2 FAM110D FAM110D CCP110 CCP110 F2RL1 F2RL1 MCIDAS MCIDAS CCL21 CCL21 RAP1GAP RAP1GAP FNBP1L FNBP1L SAXO2 SAXO2 CYLD CYLD ATG5 ATG5 CAPZB CAPZB WASF2 WASF2 LOC111165935 LOC111165935 HTT HTT ABI3 ABI3 RAB5A RAB5A CCDC151 CCDC151 EVI5L EVI5L LOC111167402 LOC111167402 GAP43 GAP43 HAP1 HAP1 FAM110B FAM110B FAM110C FAM110C RP1 RP1 DCDC2 DCDC2 RIPOR2 RIPOR2 SH3YL1 SH3YL1 MIEN1 MIEN1 ARHGAP24 ARHGAP24 BIN3 BIN3 LOC111169074 LOC111169074 WAS WAS LOC111171053 LOC111171053 FXR1 FXR1 MYO3B MYO3B ARF6 ARF6 FSCN1 FSCN1 SYNE2 SYNE2 BRK1 BRK1 LOC111170865 LOC111170865 NEURL1 NEURL1 RAB17 RAB17 PLEKHM1 PLEKHM1 MSTN MSTN TAPT1 TAPT1 LOC111171305 LOC111171305 DMTN DMTN LOC111171402 LOC111171402 LOC111171304 LOC111171304 YAP1 YAP1 SLIT2 SLIT2 LOC111170545 LOC111170545 PALM PALM CDKL5 CDKL5 HRAS HRAS EPS8L2 EPS8L2 FMR1 FMR1 CEP135 CEP135 LOC111167795 LOC111167795 CDC42 CDC42 CORO1C CORO1C KIF24 KIF24 LOC111187154 LOC111187154 TGFBR1 TGFBR1 ATG3 ATG3 TESK1 TESK1 CCDC88A CCDC88A MTOR MTOR EPHA2 EPHA2 CROCC CROCC PIK3R1 PIK3R1 CNTROB CNTROB CDC42EP1 CDC42EP1 WRAP73 WRAP73 KCTD17 KCTD17 MPHOSPH9 MPHOSPH9 P2RX7 P2RX7 NDEL1 NDEL1 ARAP1 ARAP1 TRPM2 TRPM2 FXR2 FXR2 COBL COBL RALA RALA RAC2 RAC2 FAM110A FAM110A IFT140 IFT140 CEP97 CEP97 SRC SRC PPP1R16B PPP1R16B DPYSL3 DPYSL3 FER FER APC APC RABEP2 RABEP2 ACTR3 ACTR3 CYFIP1 CYFIP1 CLN3 CLN3 CDC42EP2 CDC42EP2 CDC42EP4 CDC42EP4 SEPT9 SEPT9 MAK MAK FAM98C FAM98C CDC42EP5 CDC42EP5 CEP120 CEP120 PPP1R35 PPP1R35 AUTS2 AUTS2 FUZ FUZ EPS8L1 EPS8L1 LOC111181371 LOC111181371 DEF8 DEF8 ARHGAP35 ARHGAP35 PFN2 PFN2 ATP8B1 ATP8B1 MARK4 MARK4 GDI2 GDI2 ODF2L ODF2L PODXL PODXL LOC111162707 LOC111162707 CCL19 CCL19 CAV1 CAV1 CLRN1 CLRN1 DAAM2 DAAM2 ANLN ANLN SDCCAG8 SDCCAG8 EPS8 EPS8 ATMIN ATMIN CDK10 CDK10 NRP1 NRP1 MYO10 MYO10 SDCCAG3 SDCCAG3 SRF SRF LOC111177354 LOC111177354 AKIRIN1 AKIRIN1 ODF2 ODF2 KLF5 KLF5 TACSTD2 TACSTD2 DZIP1 DZIP1 LOC111177369 LOC111177369 MYO3A MYO3A BBS4 BBS4 DYNC2LI1 DYNC2LI1 KANK1 KANK1 ACTR3B ACTR3B EVL EVL WNT1 WNT1 FAM98A FAM98A
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (733 aa)
CDC42EP3Cdc42 effector protein 3. (265 aa)
PLEK2Pleckstrin-2. (353 aa)
PLCE1Phosphoinositide phospholipase C. (1811 aa)
VDAC3Voltage-dependent anion-selective channel protein 3. (283 aa)
IFT88Intraflagellar transport protein 88 homolog isoform X1. (825 aa)
CENPJCentromere protein J. (1354 aa)
RHOQRho-related GTP-binding protein RhoQ. (169 aa)
TWF1Twinfilin-1. (350 aa)
SAXO1Stabilizer of axonemal microtubules 1. (460 aa)
ZMYND10Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family. (440 aa)
PLD1Phospholipase. (1151 aa)
NCKAP1Nck-associated protein 1 isoform X1. (1134 aa)
GPM6ANeuronal membrane glycoprotein M6-a isoform X1. (293 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
TBC1D30TBC1 domain family member 30 isoform X1. (911 aa)
RCC2Protein RCC2 isoform X1. (543 aa)
FAM110DProtein FAM110D. (304 aa)
CCP110Centriolar coiled-coil protein of 110 kDa isoform X1. (1012 aa)
F2RL1Proteinase-activated receptor 2. (315 aa)
MCIDASMulticilin. (380 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
RAP1GAPRap1 GTPase-activating protein 1 isoform X1. (767 aa)
FNBP1LFormin-binding protein 1-like isoform X3. (609 aa)
SAXO2LOW QUALITY PROTEIN: stabilizer of axonemal microtubules 2. (446 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD isoform X1; Belongs to the peptidase C19 family. (953 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (277 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (498 aa)
LOC111165935Ras-like protein isoform X1. (285 aa)
HTTHuntingtin isoform X9. (3125 aa)
ABI3ABI gene family member 3 isoform X1. (359 aa)
RAB5ARas-related protein Rab-5A isoform X1. (215 aa)
CCDC151Coiled-coil domain-containing protein 151 isoform X1. (617 aa)
EVI5LEVI5-like protein isoform X1. (805 aa)
LOC111167402LOW QUALITY PROTEIN: cdc42 effector protein 3-like. (250 aa)
GAP43Neuromodulin. (242 aa)
HAP1LOW QUALITY PROTEIN: huntingtin-associated protein 1. (651 aa)
FAM110BProtein FAM110B. (370 aa)
FAM110CProtein FAM110C. (321 aa)
RP1Oxygen-regulated protein 1. (2137 aa)
DCDC2Doublecortin domain-containing protein 2. (473 aa)
RIPOR2Rho family-interacting cell polarization regulator 2 isoform X2. (1048 aa)
SH3YL1SH3 domain-containing YSC84-like protein 1 isoform X1. (342 aa)
MIEN1Migration and invasion enhancer 1. (115 aa)
ARHGAP24Rho GTPase-activating protein 24 isoform X1. (748 aa)
BIN3Bridging integrator 3 isoform X1. (253 aa)
LOC111169074Dedicator of cytokinesis protein 11 isoform X1; Belongs to the DOCK family. (735 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
LOC111171053Dedicator of cytokinesis protein 11-like isoform X1. (456 aa)
FXR1Fragile X mental retardation syndrome-related protein 1 isoform X1. (650 aa)
MYO3Bmyosin-IIIb isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1407 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
FSCN1Fascin. (493 aa)
SYNE2Nesprin-2 isoform X1. (6919 aa)
BRK1Protein BRICK1. (75 aa)
LOC111170865Protein Simiate-like isoform X1. (223 aa)
NEURL1E3 ubiquitin-protein ligase NEURL1 isoform X1. (574 aa)
RAB17Ras-related protein Rab-17. (213 aa)
PLEKHM1Pleckstrin homology domain-containing family M member 1 isoform X1. (1089 aa)
MSTNGrowth/differentiation factor 8. (375 aa)
TAPT1Transmembrane anterior posterior transformation protein 1 homolog. (759 aa)
LOC111171305Protein Simiate. (99 aa)
DMTNDematin isoform X1. (405 aa)
LOC111171402Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (88 aa)
LOC111171304Protein Simiate-like. (99 aa)
YAP1Transcriptional coactivator YAP1 isoform X1. (511 aa)
SLIT2Slit homolog 2 protein isoform X1. (1534 aa)
LOC111170545Rho-related GTP-binding protein RhoG. (191 aa)
PALMParalemmin-1 isoform X1. (391 aa)
CDKL5Cyclin-dependent kinase-like 5 isoform X1. (960 aa)
HRASGTPase HRas isoform X1. (189 aa)
EPS8L2Epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X1. (714 aa)
FMR1Synaptic functional regulator FMR1 isoform X1. (632 aa)
CEP135Centrosomal protein of 135 kDa isoform X1. (1148 aa)
LOC111167795Rho-related GTP-binding protein RhoG-like isoform X1. (230 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
KIF24Kinesin-like protein KIF24 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1388 aa)
LOC111187154Ephrin type-A receptor 2-like. (171 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ATG3Autophagy-related protein 3. (314 aa)
TESK1Dual specificity testis-specific protein kinase 1 isoform X1. (628 aa)
CCDC88AGirdin isoform X1. (2055 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
CROCCRootletin isoform X1. (2013 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
CNTROBCentrobin isoform X1. (902 aa)
CDC42EP1Cdc42 effector protein 1. (361 aa)
WRAP73WD repeat-containing protein WRAP73 isoform X2. (531 aa)
KCTD17BTB/POZ domain-containing protein KCTD17 isoform X1. (373 aa)
MPHOSPH9M-phase phosphoprotein 9 isoform X1. (1180 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
NDEL1Nuclear distribution protein nudE-like 1 isoform X1. (346 aa)
ARAP1arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1. (1455 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1497 aa)
FXR2Fragile X mental retardation syndrome-related protein 2. (673 aa)
COBLProtein cordon-bleu isoform X3. (1381 aa)
RALARas-related protein Ral-A. (206 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X2. (192 aa)
FAM110AProtein FAM110A. (295 aa)
IFT140Intraflagellar transport protein 140 homolog isoform X1. (1489 aa)
CEP97Centrosomal protein of 97 kDa isoform X1. (876 aa)
SRCTyrosine-protein kinase. (562 aa)
PPP1R16BProtein phosphatase 1 regulatory inhibitor subunit 16B. (568 aa)
DPYSL3Dihydropyrimidinase-related protein 3 isoform X2. (684 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
APCAdenomatous polyposis coli protein isoform X1. (2864 aa)
RABEP2Rab GTPase-binding effector protein 2 isoform X1. (592 aa)
ACTR3Actin-related protein 3; Belongs to the actin family. (418 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
CLN3Battenin. (436 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (214 aa)
CDC42EP4Cdc42 effector protein 4. (351 aa)
SEPT9Septin-9 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (578 aa)
MAKSerine/threonine-protein kinase MAK. (648 aa)
FAM98CProtein FAM98C. (350 aa)
CDC42EP5Cdc42 effector protein 5. (153 aa)
CEP120Centrosomal protein of 120 kDa isoform X1. (982 aa)
PPP1R35Protein phosphatase 1 regulatory subunit 35 isoform X1. (359 aa)
AUTS2Autism susceptibility gene 2 protein. (1264 aa)
FUZProtein fuzzy homolog isoform X1. (474 aa)
EPS8L1Epidermal growth factor receptor kinase substrate 8-like protein 1 isoform X2. (703 aa)
LOC111181371TBC1 domain family member 7 isoform X1. (293 aa)
DEF8Differentially expressed in FDCP 8 homolog isoform X1. (451 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
PFN2Profilin; Belongs to the profilin family. (197 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
MARK4Non-specific serine/threonine protein kinase. (752 aa)
GDI2Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (445 aa)
ODF2LOuter dense fiber protein 2-like isoform X1. (643 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (532 aa)
LOC111162707LIM domain kinase 2 isoform X1. (837 aa)
CCL19C-C motif chemokine. (159 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CLRN1Clarin-1 isoform X2. (246 aa)
DAAM2Disheveled-associated activator of morphogenesis 2 isoform X1. (1097 aa)
ANLNAnillin isoform X1. (1125 aa)
SDCCAG8Serologically defined colon cancer antigen 8 isoform X1. (708 aa)
EPS8Epidermal growth factor receptor kinase substrate 8. (818 aa)
ATMINATM interactor isoform X1. (828 aa)
CDK10Cyclin-dependent kinase 10 isoform X2; Belongs to the protein kinase superfamily. (404 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
MYO10Unconventional myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2055 aa)
SDCCAG3Serologically defined colon cancer antigen 3 isoform X1. (430 aa)
SRFSerum response factor isoform X2. (535 aa)
LOC111177354LOW QUALITY PROTEIN: protein Simiate-like. (187 aa)
AKIRIN1Akirin-1 isoform X1. (206 aa)
ODF2Outer dense fiber protein 2 isoform X1. (916 aa)
KLF5Krueppel-like factor 5. (454 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (323 aa)
DZIP1Zinc finger protein DZIP1 isoform X1. (853 aa)
LOC111177369Protein Simiate-like. (98 aa)
MYO3Amyosin-IIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1621 aa)
BBS4Bardet-Biedl syndrome 4 protein isoform X1. (528 aa)
DYNC2LI1Cytoplasmic dynein 2 light intermediate chain 1. (351 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1 isoform X3. (1351 aa)
ACTR3BActin-related protein 3B isoform X1; Belongs to the actin family. (556 aa)
EVLena/VASP-like protein isoform X1. (436 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FAM98AProtein FAM98A. (517 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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