(6 nodes) Morphogenesis of an epithelial bud network (Delphinapterus leucas)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	BMP4	Bone morphogenetic protein 4 isoform X2. (408 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	SOSTDC1	Sclerostin domain-containing protein 1. (206 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	FGF10	A0A2Y9MV04	A0A2Y9LQ50	Bone morphogenetic protein 4 isoform X2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.765
BMP4	NOG	A0A2Y9MV04	A0A2Y9LFG3	Bone morphogenetic protein 4 isoform X2.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.995
FGF10	BMP4	A0A2Y9LQ50	A0A2Y9MV04	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4 isoform X2.	0.765
FGF10	NOG	A0A2Y9LQ50	A0A2Y9LFG3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.765
NOG	BMP4	A0A2Y9LFG3	A0A2Y9MV04	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 4 isoform X2.	0.995
NOG	FGF10	A0A2Y9LFG3	A0A2Y9LQ50	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.765