STRINGSTRING
CAV3 CAV3 SBNO2 SBNO2 COL1A1 COL1A1 BMPR1A BMPR1A SEMA4D SEMA4D MMP2 MMP2 THBS3 THBS3 MED1 MED1 FOXH1 FOXH1 ADGRG6 ADGRG6 HEY2 HEY2 TEK TEK EGLN1 EGLN1 NOG NOG FHL2 FHL2 TGFBR1 TGFBR1 BMP7 BMP7 CHD7 CHD7 FBN2 FBN2 PPARGC1B PPARGC1B DLL4 DLL4 S1PR1 S1PR1 NOTCH1 NOTCH1 SRF SRF ENG ENG RHOA RHOA WNT10B WNT10B SOS1 SOS1 PLXNB1 PLXNB1 ADAMTS1 ADAMTS1 SFRP1 SFRP1 HEG1 HEG1 BMP10 BMP10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
SBNO2Protein strawberry notch homolog 2 isoform X1. (1383 aa)
COL1A1Collagen alpha-1(I) chain. (1463 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SEMA4Dsemaphorin-4D isoform X1; Belongs to the semaphorin family. (863 aa)
MMP272 kDa type IV collagenase. (661 aa)
THBS3Thrombospondin-3 isoform X4. (957 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
FOXH1Forkhead box protein H1. (360 aa)
ADGRG6Adhesion G-protein coupled receptor G6 isoform X1; Belongs to the G-protein coupled receptor 2 family. (1252 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
EGLN1Egl nine homolog 1. (439 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
FHL2Four and a half LIM domains protein 2. (279 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
CHD7chromodomain-helicase-DNA-binding protein 7 isoform X1. (3050 aa)
FBN2Fibrillin-2. (2912 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1. (1173 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
S1PR1Sphingosine 1-phosphate receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (455 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
SRFSerum response factor isoform X2. (535 aa)
ENGEndoglin. (652 aa)
RHOATransforming protein RhoA. (193 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
PLXNB1plexin-B1 isoform X1. (2182 aa)
ADAMTS1A disintegrin and metalloproteinase with thrombospondin motifs 1. (940 aa)
SFRP1Secreted frizzled-related protein 1. (308 aa)
HEG1Protein HEG homolog 1 isoform X1. (1474 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.