48 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATF3	Cyclic AMP-dependent transcription factor ATF-3 isoform X1. (221 aa)
	LIF	Leukemia inhibitory factor. (202 aa)
	DUSP6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
	EPHB2	Ephrin type-B receptor 2 isoform X1. (987 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type 2 isoform X3. (474 aa)
	ITGB1BP1	Integrin beta-1-binding protein 1 isoform X1. (206 aa)
	PIN1	Peptidyl-prolyl cis-trans isomerase. (163 aa)
	PSCA	Prostate stem cell antigen. (124 aa)
	PHB	Prohibitin. (272 aa)
	LYN	Tyrosine-protein kinase. (518 aa)
	EZR	Ezrin. (586 aa)
	FLCN	Folliculin isoform X1. (591 aa)
	PTPRC	Receptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
	GPER1	G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
	NLRP6	LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 6. (876 aa)
	DLG1	Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
	DUSP9	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
	PTPRR	Receptor-type tyrosine-protein phosphatase R. (653 aa)
	EPHA4	Ephrin type-A receptor 4 isoform X1. (986 aa)
	SYNJ2BP	Synaptojanin-2-binding protein isoform X1. (150 aa)
	CUNH3orf33	Protein C3orf33 homolog isoform X1. (362 aa)
	DUSP4	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (396 aa)
	TLR9	LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa)
	DUSP26	Dual specificity protein phosphatase 26 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (292 aa)
	C1QL4	Complement C1q-like protein 4. (238 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1 isoform X1. (1259 aa)
	EMILIN1	EMILIN-1. (1015 aa)
	SPRY2	Protein sprouty homolog 2. (315 aa)
	ABL1	Tyrosine-protein kinase. (1148 aa)
	DAB2IP	Disabled homolog 2-interacting protein isoform X1. (1193 aa)
	DUSP10	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
	SMAD4	Mothers against decapentaplegic homolog. (553 aa)
	RANBP9	Ran-binding protein 9. (499 aa)
	VRK3	Inactive serine/threonine-protein kinase VRK3 isoform X1. (447 aa)
	SPRED1	Sprouty-related, EVH1 domain-containing protein 1 isoform X1. (445 aa)
	NDRG2	Protein NDRG2 isoform X1. (357 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
	SEMA6A	semaphorin-6A isoform X1; Belongs to the semaphorin family. (1044 aa)
	TNIP1	TNFAIP3-interacting protein 1 isoform X1. (634 aa)
	TBC1D10C	Carabin isoform X1. (458 aa)
	SPRY4	Protein sprouty homolog 4. (299 aa)
	DUPD1	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (230 aa)
	DLG2	Disks large homolog 2 isoform X1. (994 aa)
	SPRY1	Protein sprouty homolog 1. (319 aa)
	FBLN1	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (451 aa)
	TIMP3	Metalloproteinase inhibitor 3. (211 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	EPHA4	A0A2Y9NX24	A0A2Y9N2K4	Tyrosine-protein kinase.	Ephrin type-A receptor 4 isoform X1.	0.928
ABL1	EPHB2	A0A2Y9NX24	A0A2Y9LFX1	Tyrosine-protein kinase.	Ephrin type-B receptor 2 isoform X1.	0.927
ABL1	RAPGEF1	A0A2Y9NX24	A0A2Y9NJ55	Tyrosine-protein kinase.	Rap guanine nucleotide exchange factor 1 isoform X1.	0.519
DLG1	DLG2	A0A2Y9MQM0	A0A2Y9PW00	Disks large homolog 1 isoform X1; Belongs to the MAGUK family.	Disks large homolog 2 isoform X1.	0.901
DLG2	DLG1	A0A2Y9PW00	A0A2Y9MQM0	Disks large homolog 2 isoform X1.	Disks large homolog 1 isoform X1; Belongs to the MAGUK family.	0.901
DUPD1	VRK3	A0A2Y9PUS7	A0A2Y9PBP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Inactive serine/threonine-protein kinase VRK3 isoform X1.	0.455
DUSP26	VRK3	A0A2Y9NCC5	A0A2Y9PBP3	Dual specificity protein phosphatase 26 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Inactive serine/threonine-protein kinase VRK3 isoform X1.	0.455
DUSP3	PTPRR	A0A2Y9MG84	A0A2Y9N2A0	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Receptor-type tyrosine-protein phosphatase R.	0.910
DUSP3	VRK3	A0A2Y9MG84	A0A2Y9PBP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Inactive serine/threonine-protein kinase VRK3 isoform X1.	0.940
DUSP4	SPRY2	A0A2Y9N604	A0A2Y9NMR6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein sprouty homolog 2.	0.439
DUSP4	SPRY4	A0A2Y9N604	A0A2Y9PQR2	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein sprouty homolog 4.	0.501
DUSP6	DUSP9	A0A2Y9LEU5	A0A2Y9MWV7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.426
DUSP6	SPRED1	A0A2Y9LEU5	A0A2Y9PD74	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Sprouty-related, EVH1 domain-containing protein 1 isoform X1.	0.456
DUSP6	SPRY2	A0A2Y9LEU5	A0A2Y9NMR6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein sprouty homolog 2.	0.559
DUSP6	SPRY4	A0A2Y9LEU5	A0A2Y9PQR2	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein sprouty homolog 4.	0.600
DUSP6	VRK3	A0A2Y9LEU5	A0A2Y9PBP3	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Inactive serine/threonine-protein kinase VRK3 isoform X1.	0.457
DUSP9	DUSP6	A0A2Y9MWV7	A0A2Y9LEU5	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.426
DUSP9	PTPN1	A0A2Y9MWV7	A0A2Y9QD78	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase non-receptor type.	0.491
EPHA4	ABL1	A0A2Y9N2K4	A0A2Y9NX24	Ephrin type-A receptor 4 isoform X1.	Tyrosine-protein kinase.	0.928
EPHA4	EPHB2	A0A2Y9N2K4	A0A2Y9LFX1	Ephrin type-A receptor 4 isoform X1.	Ephrin type-B receptor 2 isoform X1.	0.538