STRINGSTRING
PYCARD PYCARD ADTRP ADTRP CSF1 CSF1 ITGB3 ITGB3 TRPV4 TRPV4 CREB3 CREB3 ECM1 ECM1 CD99L2 CD99L2 CX3CR1 CX3CR1 CALR CALR MOSPD2 MOSPD2 CUNH10orf99 CUNH10orf99 SLAMF1 SLAMF1 RIPOR2 RIPOR2 CCR6 CCR6 XCL1 XCL1 LYN LYN IL27RA IL27RA S100A14 S100A14 OXSR1 OXSR1 MAPK1 MAPK1 CRKL CRKL CXCL14 CXCL14 DEFB124 DEFB124 MAPK3 MAPK3 SPN SPN CRK CRK STK10 STK10 CSF1R CSF1R FADD FADD CXCL13 CXCL13 PADI2 PADI2 CMKLR1 CMKLR1 GCSAM GCSAM CXCL10 CXCL10 DUSP1 DUSP1 PTK2B PTK2B AIRE AIRE C1QBP C1QBP SPNS2 SPNS2 CCR7 CCR7 TNFSF14 TNFSF14 NOV NOV CORO1A CORO1A CCL5 CCL5 CCL27 CCL27 LOC111163731 LOC111163731 CCL21 CCL21 LOC111185731 LOC111185731 MSN MSN AIF1 AIF1 TMEM102 TMEM102 AGER AGER SLIT2 SLIT2 MSTN MSTN LOC111171403 LOC111171403 CCL20 CCL20 CXCL12 CXCL12 APOD APOD MADCAM1 MADCAM1 STK39 STK39 CCR1 CCR1 ADAM8 ADAM8 JAM2 JAM2 WNT5A WNT5A LRCH1 LRCH1 LGALS3 LGALS3 RHOA RHOA ANO6 ANO6 CCR2 CCR2 IL12A IL12A RARRES2 RARRES2 DOCK8 DOCK8 APP APP LGMN LGMN GAS6 GAS6 AKIRIN1 AKIRIN1 C3AR1 C3AR1 ADAM10 ADAM10 PLA2G7 PLA2G7 WNK1 WNK1 ABL1 ABL1 WASL WASL IL34 IL34 C5AR1 C5AR1 NEDD9 NEDD9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PYCARDApoptosis-associated speck-like protein containing a CARD. (195 aa)
ADTRPAndrogen-dependent TFPI-regulating protein isoform X1. (230 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (370 aa)
ECM1Extracellular matrix protein 1 isoform X1. (544 aa)
CD99L2CD99 antigen-like protein 2 isoform X1. (300 aa)
CX3CR1CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (475 aa)
CALRCalreticulin. (417 aa)
MOSPD2Motile sperm domain-containing protein 2 isoform X1. (518 aa)
CUNH10orf99Secreted protein C10orf99 homolog. (81 aa)
SLAMF1Signaling lymphocytic activation molecule isoform X1. (378 aa)
RIPOR2Rho family-interacting cell polarization regulator 2 isoform X2. (1048 aa)
CCR6C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
XCL1Lymphotactin. (111 aa)
LYNTyrosine-protein kinase. (518 aa)
IL27RAInterleukin-27 receptor subunit alpha isoform X1. (656 aa)
S100A14Protein S100-A14; Belongs to the S-100 family. (104 aa)
OXSR1Serine/threonine-protein kinase OSR1. (523 aa)
MAPK1Mitogen-activated protein kinase. (380 aa)
CRKLCrk-like protein. (303 aa)
CXCL14C-X-C motif chemokine 14. (99 aa)
DEFB124Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (70 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
SPNLeukosialin. (411 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
STK10Serine/threonine-protein kinase 10. (967 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
CXCL13C-X-C motif chemokine 13. (109 aa)
PADI2Protein-arginine deiminase type-2. (665 aa)
CMKLR1Chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (365 aa)
GCSAMGerminal center-associated signaling and motility protein. (138 aa)
CXCL10C-X-C motif chemokine. (103 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
AIREAutoimmune regulator. (553 aa)
C1QBPComplement component 1 Q subcomponent-binding protein, mitochondrial. (278 aa)
SPNS2Protein spinster homolog 2 isoform X4. (549 aa)
CCR7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
TNFSF14Tumor necrosis factor ligand superfamily member 14 isoform X1. (241 aa)
NOVProtein NOV homolog. (359 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CCL5C-C motif chemokine. (91 aa)
CCL27LOW QUALITY PROTEIN: C-C motif chemokine 27. (117 aa)
LOC111163731C-C motif chemokine. (93 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
LOC111185731C-C motif chemokine. (99 aa)
MSNMoesin isoform X1. (579 aa)
AIF1Allograft inflammatory factor 1 isoform X1. (162 aa)
TMEM102LOW QUALITY PROTEIN: transmembrane protein 102. (506 aa)
AGERAdvanced glycosylation end product-specific receptor isoform X1. (631 aa)
SLIT2Slit homolog 2 protein isoform X1. (1534 aa)
MSTNGrowth/differentiation factor 8. (375 aa)
LOC111171403LOW QUALITY PROTEIN: transmembrane protein 102-like. (288 aa)
CCL20C-C motif chemokine. (97 aa)
CXCL12Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
APODApolipoprotein D. (213 aa)
MADCAM1Mucosal addressin cell adhesion molecule 1. (406 aa)
STK39STE20/SPS1-related proline-alanine-rich protein kinase isoform X1. (539 aa)
CCR1C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa)
JAM2Junctional adhesion molecule B isoform X1. (350 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
LRCH1Leucine-rich repeat and calponin homology domain-containing protein 1 isoform X7. (762 aa)
LGALS3Galectin. (256 aa)
RHOATransforming protein RhoA. (193 aa)
ANO6Anoctamin. (951 aa)
CCR2C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
RARRES2Retinoic acid receptor responder protein 2. (166 aa)
DOCK8Dedicator of cytokinesis protein 8 isoform X1; Belongs to the DOCK family. (2098 aa)
APPAmyloid beta A4 protein isoform X1. (767 aa)
LGMNLegumain. (433 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
AKIRIN1Akirin-1 isoform X1. (206 aa)
C3AR1C3a anaphylatoxin chemotactic receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (498 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (748 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (443 aa)
WNK1Serine/threonine-protein kinase WNK1 isoform X1. (2825 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
WASLNeural Wiskott-Aldrich syndrome protein isoform X1. (510 aa)
IL34Interleukin-34. (235 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (424 aa)
NEDD9Enhancer of filamentation 1 isoform X1. (829 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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