52 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RHOA	Transforming protein RhoA. (193 aa)
	ANO6	Anoctamin. (951 aa)
	IL12A	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
	CCR2	C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	DOCK8	Dedicator of cytokinesis protein 8 isoform X1; Belongs to the DOCK family. (2098 aa)
	APP	Amyloid beta A4 protein isoform X1. (767 aa)
	LGMN	Legumain. (433 aa)
	GAS6	Growth arrest-specific protein 6. (671 aa)
	ADAM10	Disintegrin and metalloproteinase domain-containing protein 10. (748 aa)
	PLA2G7	Platelet-activating factor acetylhydrolase. (443 aa)
	WNK1	Serine/threonine-protein kinase WNK1 isoform X1. (2825 aa)
	ABL1	Tyrosine-protein kinase. (1148 aa)
	NEDD9	Enhancer of filamentation 1 isoform X1. (829 aa)
	PYCARD	Apoptosis-associated speck-like protein containing a CARD. (195 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (789 aa)
	CXCL14	C-X-C motif chemokine 14. (99 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
	DEFB124	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (70 aa)
	C1QBP	Complement component 1 Q subcomponent-binding protein, mitochondrial. (278 aa)
	PTK2B	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
	CXCL10	C-X-C motif chemokine. (103 aa)
	CXCL13	C-X-C motif chemokine 13. (109 aa)
	CREB3	Cyclic AMP-responsive element-binding protein 3. (370 aa)
	LOC111163731	C-C motif chemokine. (93 aa)
	CCL21	C-C motif chemokine 21 isoform X1. (131 aa)
	CCL27	LOW QUALITY PROTEIN: C-C motif chemokine 27. (117 aa)
	CCL5	C-C motif chemokine. (91 aa)
	TNFSF14	Tumor necrosis factor ligand superfamily member 14 isoform X1. (241 aa)
	CCR7	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	OXSR1	Serine/threonine-protein kinase OSR1. (523 aa)
	S100A14	Protein S100-A14; Belongs to the S-100 family. (104 aa)
	XCL1	Lymphotactin. (111 aa)
	CCR6	C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
	SLAMF1	Signaling lymphocytic activation molecule isoform X1. (378 aa)
	MOSPD2	Motile sperm domain-containing protein 2 isoform X1. (518 aa)
	CALR	Calreticulin. (417 aa)
	CX3CR1	CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (475 aa)
	CD99L2	CD99 antigen-like protein 2 isoform X1. (300 aa)
	AIF1	Allograft inflammatory factor 1 isoform X1. (162 aa)
	TMEM102	LOW QUALITY PROTEIN: transmembrane protein 102. (506 aa)
	AGER	Advanced glycosylation end product-specific receptor isoform X1. (631 aa)
	LOC111171403	LOW QUALITY PROTEIN: transmembrane protein 102-like. (288 aa)
	CCL20	C-C motif chemokine. (97 aa)
	CXCL12	Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
	MADCAM1	Mucosal addressin cell adhesion molecule 1. (406 aa)
	STK39	STE20/SPS1-related proline-alanine-rich protein kinase isoform X1. (539 aa)
	CCR1	C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	ADAM8	Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa)
	JAM2	Junctional adhesion molecule B isoform X1. (350 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
	LGALS3	Galectin. (256 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	APP	A0A2Y9NR06	A0A2Y9NJ25	Disintegrin and metalloproteinase domain-containing protein 10.	Amyloid beta A4 protein isoform X1.	0.712
ADAM10	CX3CR1	A0A2Y9NR06	A0A2Y9MCB7	Disintegrin and metalloproteinase domain-containing protein 10.	CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.502
AGER	APP	A0A2Y9MJV2	A0A2Y9NJ25	Advanced glycosylation end product-specific receptor isoform X1.	Amyloid beta A4 protein isoform X1.	0.616
AIF1	CX3CR1	A0A2Y9MIU7	A0A2Y9MCB7	Allograft inflammatory factor 1 isoform X1.	CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.428
AIF1	PYCARD	A0A2Y9MIU7	A0A2Y9PAE2	Allograft inflammatory factor 1 isoform X1.	Apoptosis-associated speck-like protein containing a CARD.	0.475
APP	ADAM10	A0A2Y9NJ25	A0A2Y9NR06	Amyloid beta A4 protein isoform X1.	Disintegrin and metalloproteinase domain-containing protein 10.	0.712
APP	AGER	A0A2Y9NJ25	A0A2Y9MJV2	Amyloid beta A4 protein isoform X1.	Advanced glycosylation end product-specific receptor isoform X1.	0.616
APP	CALR	A0A2Y9NJ25	A0A2Y9MA80	Amyloid beta A4 protein isoform X1.	Calreticulin.	0.546
C1QBP	RHOA	A0A2Y9Q2N5	A0A2Y9NBP6	Complement component 1 Q subcomponent-binding protein, mitochondrial.	Transforming protein RhoA.	0.400
CALR	APP	A0A2Y9MA80	A0A2Y9NJ25	Calreticulin.	Amyloid beta A4 protein isoform X1.	0.546
CCL20	CCL21	A0A2Y9MNZ7	A0A2Y9LF88	C-C motif chemokine.	C-C motif chemokine 21 isoform X1.	0.801
CCL20	CCL27	A0A2Y9MNZ7	A0A2Y9LJX6	C-C motif chemokine.	LOW QUALITY PROTEIN: C-C motif chemokine 27.	0.695
CCL20	CCL5	A0A2Y9MNZ7	A0A2Y9LMK7	C-C motif chemokine.	C-C motif chemokine.	0.804
CCL20	CCR1	A0A2Y9MNZ7	A0A2Y9N328	C-C motif chemokine.	C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.864
CCL20	CCR2	A0A2Y9MNZ7	A0A2Y9NIG5	C-C motif chemokine.	C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family.	0.905
CCL20	CCR6	A0A2Y9MNZ7	A0A2Y9M3Y9	C-C motif chemokine.	C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family.	0.999
CCL20	CCR7	A0A2Y9MNZ7	A0A2Y9LWJ5	C-C motif chemokine.	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	0.930
CCL20	CX3CR1	A0A2Y9MNZ7	A0A2Y9MCB7	C-C motif chemokine.	CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.860
CCL20	CXCL10	A0A2Y9MNZ7	A0A2Y9Q7R7	C-C motif chemokine.	C-X-C motif chemokine.	0.769
CCL20	CXCL12	A0A2Y9MNZ7	A0A2Y9MS30	C-C motif chemokine.	Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family.	0.752