STRINGSTRING
EPHA2 EPHA2 ITGB1BP1 ITGB1BP1 EFR3A EFR3A ACTN2 ACTN2 MRAP MRAP PRAM1 PRAM1 RAB8A RAB8A WNK3 WNK3 ARHGAP44 ARHGAP44 F11R F11R DCHS1 DCHS1 PIP5K1A PIP5K1A GORASP1 GORASP1 GRIPAP1 GRIPAP1 SCN3B SCN3B GOLPH3L GOLPH3L MRAP2 MRAP2 TSPAN17 TSPAN17 RAB7A RAB7A FLNA FLNA PALM PALM LOC111171019 LOC111171019 ANKRD28 ANKRD28 NSG1 NSG1 S100A10 S100A10 SEC13 SEC13 CAV3 CAV3 PKP3 PKP3 ANKRD44 ANKRD44 DLG1 DLG1 ZFYVE27 ZFYVE27 RAMP1 RAMP1 SLC4A1 SLC4A1 EXOC5 EXOC5 SEC23A SEC23A FLOT1 FLOT1 ZDHHC2 ZDHHC2 LOC111173542 LOC111173542 MPP5 MPP5 ATP6AP1 ATP6AP1 FAM126B FAM126B SLMAP SLMAP IKBKB IKBKB EHD3 EHD3 EFR3B EFR3B GRIP1 GRIP1 KRT18 KRT18 GORASP2 GORASP2 RAB3B RAB3B RAB15 RAB15 TTC7B TTC7B TTC8 TTC8 ZDHHC22 ZDHHC22 DPP6 DPP6 DENND4C DENND4C TTC7A TTC7A PREPL PREPL LRP6 LRP6 PACS2 PACS2 STXBP1 STXBP1 RAB10 RAB10 SEC16A SEC16A GAS6 GAS6 GPR158 GPR158 WDR72 WDR72 RAB8B RAB8B PKP2 PKP2 LOC111178657 LOC111178657 C2CD5 C2CD5 LRRC1 LRRC1 TSPAN33 TSPAN33 TNFRSF1A TNFRSF1A ATP2C2 ATP2C2 PDZK1 PDZK1 CUNH16orf70 CUNH16orf70 RAB11A RAB11A EHD2 EHD2 RAP1A RAP1A ATP1B3 ATP1B3 PLEKHF1 PLEKHF1 TSPAN5 TSPAN5 CDH1 CDH1 ROCK1 ROCK1 FAM126A FAM126A SLC9A3R1 SLC9A3R1 NSF NSF ASB15 ASB15 RAB40B RAB40B CD81 CD81 TPBG TPBG FRMD8 FRMD8 EHD4 EHD4 CLN3 CLN3 GGA2 GGA2 LYPD1 LYPD1 BBS1 BBS1 GGA3 GGA3 EHD1 EHD1 RHBDF2 RHBDF2 SYS1 SYS1 RAB26 RAB26 TSPAN14 TSPAN14 TSPAN32 TSPAN32 TSPAN15 TSPAN15 PACS1 PACS1 KCNB2 KCNB2 DLG2 DLG2 TMEM88 TMEM88 RAB40C RAB40C INPP5K INPP5K RAMP3 RAMP3 ARFRP1 ARFRP1 SLC9A3R2 SLC9A3R2 RILPL1 RILPL1 PIGW PIGW RAB31 RAB31 RAB12 RAB12 MYL12B MYL12B PPIL2 PPIL2 GGA1 GGA1 RAB3C RAB3C FLOT2 FLOT2 LAMA5 LAMA5 TUSC5 TUSC5 PRKCZ PRKCZ KCNIP3 KCNIP3 CCDC88A CCDC88A SPTBN1 SPTBN1 TESC TESC RILPL2 RILPL2 VAMP3 VAMP3 LOC111187154 LOC111187154 GOLPH3 GOLPH3 TNF TNF BLZF1 BLZF1 RAB13 RAB13 PTCH1 PTCH1 RAMP2 RAMP2 GPR179 GPR179 VAMP5 VAMP5 RAB3A RAB3A ZDHHC23 ZDHHC23 JUP JUP GOLGA4 GOLGA4 VPS35 VPS35 RAB3D RAB3D EMP2 EMP2 BBS2 BBS2 HECTD1 HECTD1 TMEM150A TMEM150A GAK GAK CRB3 CRB3 ATP1B1 ATP1B1 EZR EZR PDZD3 PDZD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPHA2Ephrin type-A receptor 2. (975 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (206 aa)
EFR3AProtein EFR3 homolog A isoform X1. (821 aa)
ACTN2Alpha-actinin-2. (894 aa)
MRAPMelanocortin-2 receptor accessory protein isoform X1. (197 aa)
PRAM1PML-RARA-regulated adapter molecule 1 isoform X2. (541 aa)
RAB8ARas-related protein Rab-8A. (207 aa)
WNK3Serine/threonine-protein kinase WNK3 isoform X1. (1780 aa)
ARHGAP44Rho GTPase-activating protein 44 isoform X1. (809 aa)
F11RJunctional adhesion molecule A. (299 aa)
DCHS1Protocadherin-16. (3294 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa)
GORASP1Golgi reassembly-stacking protein 1 isoform X1. (486 aa)
GRIPAP1GRIP1-associated protein 1 isoform X1. (842 aa)
SCN3BSodium channel subunit beta-3. (215 aa)
GOLPH3LGolgi phosphoprotein 3-like isoform X1. (285 aa)
MRAP2Melanocortin-2 receptor accessory protein 2. (206 aa)
TSPAN17Tetraspanin. (296 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
FLNAfilamin-A isoform X1. (2647 aa)
PALMParalemmin-1 isoform X1. (391 aa)
LOC111171019Glutamate receptor-interacting protein 1-like. (206 aa)
ANKRD28Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1. (1083 aa)
NSG1Neuron-specific protein family member 1. (185 aa)
S100A10Protein S100-A10; Belongs to the S-100 family. (96 aa)
SEC13Protein SEC13 homolog isoform X1; Belongs to the WD repeat SEC13 family. (322 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
PKP3Plakophilin-3 isoform X1. (811 aa)
ANKRD44Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1. (1056 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
ZFYVE27Protrudin isoform X1. (407 aa)
RAMP1Receptor activity-modifying protein 1. (148 aa)
SLC4A1Anion exchange protein. (963 aa)
EXOC5Exocyst complex component 5. (708 aa)
SEC23AProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
ZDHHC2Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (366 aa)
LOC111173542Golgin subfamily A member 7 isoform X1. (137 aa)
MPP5MAGUK p55 subfamily member 5 isoform X1; Belongs to the MAGUK family. (675 aa)
ATP6AP1V-type proton ATPase subunit S1. (469 aa)
FAM126BProtein FAM126B isoform X1. (586 aa)
SLMAPSarcolemmal membrane-associated protein isoform X1. (847 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa)
EHD3EH domain-containing protein 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
EFR3BProtein EFR3 homolog B isoform X3. (855 aa)
GRIP1Glutamate receptor-interacting protein 1. (886 aa)
KRT18Keratin, type I cytoskeletal 18; Belongs to the intermediate filament family. (429 aa)
GORASP2Golgi reassembly-stacking protein 2 isoform X1. (453 aa)
RAB3BRas-related protein Rab-3B. (219 aa)
RAB15Ras-related protein Rab-15 isoform X1. (212 aa)
TTC7BTetratricopeptide repeat protein 7B isoform X1. (843 aa)
TTC8Tetratricopeptide repeat protein 8 isoform X1. (515 aa)
ZDHHC22Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (263 aa)
DPP6Dipeptidyl aminopeptidase-like protein 6 isoform X1; Belongs to the peptidase S9B family. (865 aa)
DENND4CDENN domain-containing protein 4C isoform X1. (1958 aa)
TTC7ATetratricopeptide repeat protein 7A isoform X1. (858 aa)
PREPLProlyl endopeptidase-like isoform X1. (727 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1614 aa)
PACS2Phosphofurin acidic cluster sorting protein 2 isoform X1. (879 aa)
STXBP1Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
RAB10Ras-related protein Rab-10. (200 aa)
SEC16AProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2373 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
GPR158Probable G-protein coupled receptor 158. (905 aa)
WDR72WD repeat-containing protein 72. (1102 aa)
RAB8BRas-related protein Rab-8B isoform X1. (207 aa)
PKP2Plakophilin-2 isoform X1. (826 aa)
LOC111178657Leucine-rich repeat-containing protein 1-like isoform X1. (174 aa)
C2CD5C2 domain-containing protein 5 isoform X1. (1051 aa)
LRRC1Leucine-rich repeat-containing protein 1. (395 aa)
TSPAN33Tetraspanin. (283 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (445 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (955 aa)
PDZK1Na(+)/H(+) exchange regulatory cofactor NHE-RF3 isoform X1. (518 aa)
CUNH16orf70UPF0183 protein C16orf70 homolog. (422 aa)
RAB11ARas-related protein Rab-11A isoform X1. (218 aa)
EHD2EH domain-containing protein 2 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
PLEKHF1Pleckstrin homology domain-containing family F member 1. (279 aa)
TSPAN5Tetraspanin. (268 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
FAM126AHyccin isoform X1. (521 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
NSFVesicle-fusing ATPase isoform X1. (777 aa)
ASB15Ankyrin repeat and SOCS box protein 15. (588 aa)
RAB40BRas-related protein Rab-40B. (278 aa)
CD81Tetraspanin. (236 aa)
TPBGTrophoblast glycoprotein. (419 aa)
FRMD8FERM domain-containing protein 8 isoform X1. (465 aa)
EHD4EH domain-containing protein 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (541 aa)
CLN3Battenin. (436 aa)
GGA2ADP-ribosylation factor-binding protein GGA2. (618 aa)
LYPD1ly6/PLAUR domain-containing protein 1. (141 aa)
BBS1Bardet-Biedl syndrome 1 protein. (593 aa)
GGA3ADP-ribosylation factor-binding protein GGA3 isoform X1. (758 aa)
EHD1EH domain-containing protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (534 aa)
RHBDF2Inactive rhomboid protein 2. (828 aa)
SYS1Protein SYS1 homolog; Involved in protein trafficking. Belongs to the SYS1 family. (156 aa)
RAB26Ras-related protein Rab-26 isoform X1. (319 aa)
TSPAN14Tetraspanin. (331 aa)
TSPAN32Tetraspanin-32 isoform X1; Belongs to the tetraspanin (TM4SF) family. (571 aa)
TSPAN15Tetraspanin. (294 aa)
PACS1Phosphofurin acidic cluster sorting protein 1 isoform X1. (960 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (912 aa)
DLG2Disks large homolog 2 isoform X1. (994 aa)
TMEM88Transmembrane protein 88. (159 aa)
RAB40CRas-related protein Rab-40C isoform X1. (281 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform X1. (476 aa)
RAMP3Receptor activity-modifying protein 3. (151 aa)
ARFRP1ADP-ribosylation factor-related protein 1 isoform X1. (201 aa)
SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform X1. (360 aa)
RILPL1RILP-like protein 1 isoform X4. (458 aa)
PIGWPhosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (502 aa)
RAB31Ras-related protein Rab-31 isoform X1. (194 aa)
RAB12Ras-related protein Rab-12 isoform X1. (244 aa)
MYL12BMyosin regulatory light chain 12B. (172 aa)
PPIL2Peptidyl-prolyl cis-trans isomerase-like 2 isoform X1. (522 aa)
GGA1ADP-ribosylation factor-binding protein GGA1 isoform X1. (648 aa)
RAB3CRas-related protein Rab-3C. (227 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
LAMA5Laminin subunit alpha-5. (3687 aa)
TUSC5Tumor suppressor candidate 5. (204 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)
KCNIP3Calsenilin isoform X1. (255 aa)
CCDC88AGirdin isoform X1. (2055 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2363 aa)
TESCCalcineurin B homologous protein 3. (214 aa)
RILPL2RILP-like protein 2 isoform X4. (320 aa)
VAMP3Vesicle-associated membrane protein 3. (104 aa)
LOC111187154Ephrin type-A receptor 2-like. (171 aa)
GOLPH3Golgi phosphoprotein 3. (298 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
BLZF1Golgin-45. (401 aa)
RAB13Ras-related protein Rab-13. (203 aa)
PTCH1Protein patched homolog 1 isoform X1. (1447 aa)
RAMP2Receptor activity-modifying protein 2. (177 aa)
GPR179Probable G-protein coupled receptor 179. (2379 aa)
VAMP5Vesicle-associated membrane protein 5. (116 aa)
RAB3ARas-related protein Rab-3A. (220 aa)
ZDHHC23Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (435 aa)
JUPJunction plakoglobin. (744 aa)
GOLGA4Golgin subfamily A member 4 isoform X1. (2275 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
RAB3DRas-related protein Rab-3D. (219 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
HECTD1E3 ubiquitin-protein ligase HECTD1 isoform X1. (2610 aa)
TMEM150ATransmembrane protein 150A. (305 aa)
GAKcyclin-G-associated kinase isoform X1. (1273 aa)
CRB3Protein crumbs homolog 3. (123 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
EZREzrin. (586 aa)
PDZD3Na(+)/H(+) exchange regulatory cofactor NHE-RF4. (501 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (12%) [HD]