STRINGSTRING
LYN LYN NOD2 NOD2 CCL21 CCL21 AMBRA1 AMBRA1 PDGFB PDGFB F2 F2 DGKZ DGKZ EPHA8 EPHA8 FGR FGR CCL19 CCL19 EEF1A2 EEF1A2 PTK2B PTK2B PIK3R4 PIK3R4 PDGFRA PDGFRA FLT1 FLT1 ATG14 ATG14 VAV2 VAV2 VAV3 VAV3 TGFB1 TGFB1 CD19 CD19 CD81 CD81 PDGFRB PDGFRB TEK TEK FGFR3 FGFR3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LYNTyrosine-protein kinase. (518 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1295 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (278 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
DGKZDiacylglycerol kinase. (1210 aa)
EPHA8Ephrin type-A receptor 8. (1005 aa)
FGRTyrosine-protein kinase. (526 aa)
CCL19C-C motif chemokine. (159 aa)
EEF1A2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (492 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
VAV3Guanine nucleotide exchange factor VAV3. (954 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
CD19B-lymphocyte antigen CD19 isoform X1. (570 aa)
CD81Tetraspanin. (236 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
FGFR3Fibroblast growth factor receptor. (805 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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