(9 nodes) Mesenchymal cell apoptotic process network (Delphinapterus leucas)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP7	Bone morphogenetic protein 7. (431 aa)
	MSX1	Homeobox protein MSX-1. (303 aa)
	HIF1A	Hypoxia-inducible factor 1-alpha isoform X1. (823 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
	ETV6	Transcription factor ETV6 isoform X1. (452 aa)
	LOC111182889	LOW QUALITY PROTEIN: transcription factor SOX-9-like. (510 aa)
	HOXA13	Homeobox protein Hox-A13. (387 aa)
	GDF5	Growth/differentiation factor 5. (499 aa)
	EDNRA	Endothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP7	GDF5	A0A2Y9QCJ3	A0A2Y9PZB9	Bone morphogenetic protein 7.	Growth/differentiation factor 5.	0.524
BMP7	LOC111182889	A0A2Y9QCJ3	A0A2Y9PEX3	Bone morphogenetic protein 7.	LOW QUALITY PROTEIN: transcription factor SOX-9-like.	0.512
BMP7	MSX1	A0A2Y9QCJ3	A0A2Y9MKV9	Bone morphogenetic protein 7.	Homeobox protein MSX-1.	0.453
BMP7	SHH	A0A2Y9QCJ3	A0A2Y9NDZ2	Bone morphogenetic protein 7.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.520
GDF5	BMP7	A0A2Y9PZB9	A0A2Y9QCJ3	Growth/differentiation factor 5.	Bone morphogenetic protein 7.	0.524
GDF5	LOC111182889	A0A2Y9PZB9	A0A2Y9PEX3	Growth/differentiation factor 5.	LOW QUALITY PROTEIN: transcription factor SOX-9-like.	0.519
HIF1A	LOC111182889	A0A2Y9MZ41	A0A2Y9PEX3	Hypoxia-inducible factor 1-alpha isoform X1.	LOW QUALITY PROTEIN: transcription factor SOX-9-like.	0.510
LOC111182889	BMP7	A0A2Y9PEX3	A0A2Y9QCJ3	LOW QUALITY PROTEIN: transcription factor SOX-9-like.	Bone morphogenetic protein 7.	0.512
LOC111182889	GDF5	A0A2Y9PEX3	A0A2Y9PZB9	LOW QUALITY PROTEIN: transcription factor SOX-9-like.	Growth/differentiation factor 5.	0.519
LOC111182889	HIF1A	A0A2Y9PEX3	A0A2Y9MZ41	LOW QUALITY PROTEIN: transcription factor SOX-9-like.	Hypoxia-inducible factor 1-alpha isoform X1.	0.510
LOC111182889	MSX1	A0A2Y9PEX3	A0A2Y9MKV9	LOW QUALITY PROTEIN: transcription factor SOX-9-like.	Homeobox protein MSX-1.	0.501
LOC111182889	SHH	A0A2Y9PEX3	A0A2Y9NDZ2	LOW QUALITY PROTEIN: transcription factor SOX-9-like.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.603
MSX1	BMP7	A0A2Y9MKV9	A0A2Y9QCJ3	Homeobox protein MSX-1.	Bone morphogenetic protein 7.	0.453
MSX1	LOC111182889	A0A2Y9MKV9	A0A2Y9PEX3	Homeobox protein MSX-1.	LOW QUALITY PROTEIN: transcription factor SOX-9-like.	0.501
MSX1	SHH	A0A2Y9MKV9	A0A2Y9NDZ2	Homeobox protein MSX-1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.529
SHH	BMP7	A0A2Y9NDZ2	A0A2Y9QCJ3	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 7.	0.520
SHH	LOC111182889	A0A2Y9NDZ2	A0A2Y9PEX3	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	LOW QUALITY PROTEIN: transcription factor SOX-9-like.	0.603
SHH	MSX1	A0A2Y9NDZ2	A0A2Y9MKV9	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Homeobox protein MSX-1.	0.529